Results 51 to 60 of about 4,606 (238)

An Investigation of Hyperostosis Frontalis Interna in a Modern Anatomical Body Donor Population

Clinical Anatomy, EarlyView.
ABSTRACT This research sought to examine the prevalence and severity of hyperostosis frontalis interna (HFI) in the Chicagoland anatomical body donor population. The study further aimed to elucidate potential demographic risk factors for HFI, including sex, age at death, and structural vulnerability index (SVI), as well as any common comorbidities, as ...
Amy C. Beresheim, Amanda Hall
wiley   +1 more source

Investigations Into the Human Metabolism of Trestolone (7α‐Methyl‐19‐Nortestosterone)

Drug Testing and Analysis, EarlyView.
As the known metabolites of 7α‐methyl‐19‐nortestosterone (MENT), M1 and M2, suffer from chromatographic issues under routine doping control conditions, the human metabolism of MENT was reinvestigated. From the numerous new metabolites detected, especially, M5 and M10 were identified as the most promising candidates to be implemented into routine ...
Thomas Piper, Gregor Fusshöller, Mario Thevis   +2 more
wiley   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Molecular Investigations on Angiogenesis and Oxidative Stress in Roe Deer (Capreolus capreolus) Bucks' Testes Throughout the Reproductive Cycle

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Animals with seasonal reproductive cycles, as the Roe deer (Capreolus capreolus), have developed mechanisms to synchronize reproduction with the environmental cycle in order to optimize reproductive success through melatonin. Angiogenesis and oxidative stress are key processes in spermatogenesis, contributing to testicular remodeling and ...
Ilaria Troisio, Domenico Ventrella, Bálint Lóránt Hausz, Mattia Cesauri, Niccolò Ian Vannetti, Maria Laura Bacci, Alberto Elmi, Augusta Zannoni   +7 more
wiley   +1 more source

Effects of testosterone and high‐dose anabolic steroids on orthodontic‐induced bone remodeling and root resorption: An animal study

Journal of Periodontology, EarlyView.
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis, Kelly Galisteu‐Luiz, Gabriela Leite Pedroso, Gustavo Lopes Puls, Leticia Cassaro, Bruno Boaventura Vieira, Fábio Lourenço Romano, Erika Calvano Küchler, Christian Kirschneck, Daniela Silva Barroso de Oliveira, Maria Bernadete Sasso Stuani, Mirian Aiko Nakane Matsumoto   +11 more
wiley   +1 more source

Exploring Raman Spectroscopy as a Detection Tool for Cardiovascular Diseases and Diabetes Mellitus in Fingernails

Journal of Raman Spectroscopy, EarlyView.
Endogenous constituents vary between fingernails of healthy, cardiovascular and diabetic participants. Raman spectroscopy yields a biochemical fingerprint of key endogenous constituents and disease‐related biomarkers. Combined with machine learning algorithms, Raman spectroscopy can classify healthy, cardiovascular and diabetic based on their Raman ...
Megan Wilson, Dhiya Al‐Jumeily, Leung Tang, Jason Birkett, Iftikhar Khan, Ismail Abbas, Matthew Harper, Sulaf Assi   +7 more
wiley   +1 more source

A Novel Male Contraceptive Pill-Patch Combination: Oral Desogestrel and Transdermal Testosterone in the Suppression of Spermatogenesis in Normal Men [PDF]

, 2001
W. M. Hair
openalex   +2 more sources

Interplay Between Sex and Cytosine‐Adenine‐Guanine‐Age Product Score in Huntington's Disease: Clinical and Neuroimaging Perspectives

Movement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a cytosine‐adenine‐guanine (CAG) repeat expansion in the huntingtin gene. The disease exhibits sex‐related differences in symptomatology and disease progression, but the effect on brain structural biomarkers and the interaction between sex and CAG‐age ...
Jingwen Yao, Grayson Feng, Guowen Shao, Zexi Wang, Adys Mendizabal, Donatello Telesca, Kaiying Fang, Lola Ibragimova, Juwairia Shoaib, Melanie A. Morrison, Janine M. Lupo   +10 more
wiley   +1 more source

Natural Sweetener Stevioside-Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia. [PDF]

Adv Healthc Mater
This study addresses limitations of minoxidil (MXD) in treating androgenetic alopecia by using stevioside (STV) as a solubilizing agent and microneedle (MN) material. STV enhanced MXD's solubility and skin absorption, leading to improved drug delivery and significant hair regrowth in animal models, demonstrating strong potential for AGA treatment ...
Zhang J, Shao T, Li H, Zhu L, Albakr L, Wheate NJ, Kang L, Wu C.   +7 more
europepmc   +2 more sources

Association of Menopause and Hormonal Contraceptive Use With Chronic Rhinosinusitis: An “All of Us” Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective The role of sex hormones in inflammation has attracted increased attention, but the impact of hormone‐modifying states in chronic rhinosinusitis (CRS) has not been thoroughly studied. We aim to investigate the association of menopause and systemic hormonal contraceptive (SHC) use with both CRS with (CRSwNP) and without (CRSsNP) nasal
Abraham Ahn, Richard G. Chiu, Kamal Eldeirawi, Anthony I. Dick, Sharmilee M. Nyenhuis, Victoria S. Lee   +5 more
wiley   +1 more source