Results 51 to 60 of about 20,312 (267)
Environmental Toxicology, Volume 38, Issue 1, Page 225-242, January 2023., 2023 Abstract Per‐ and polyfluoroalkyl substances (PFAS), which include perfluorooctanoic acid (PFOA), heptafluorobutyric acid (HFBA), and perfluorotetradecanoic acid (PFTA), are commonly occurring organic pollutants. Exposure to PFAS affects the immune system, thyroid and kidney function, lipid metabolism, and insulin signaling and is also involved in the ...
Qi Qi +6 more
wiley +1 more source
Test-based Patch Clustering for Automatically-Generated Patches Assessment [PDF]
, 2022 Previous studies have shown that Automated Program Repair (APR) techniques suffer from the overfitting problem. Overfitting happens when a patch is run and the test suite does not reveal any error, but the patch actually does not fix the underlying bug or it introduces a new defect that is not covered by the test suite. Therefore, the patches generated
arxiv +1 more source
Androgen receptors beyond prostate cancer: an old marker as a new target. [PDF]
, 2014 Androgen receptors (ARs) play a critical role in the development of prostate cancer. Targeting ARs results in important salutary effects in this malignancy.
Kurzrock, Razelle +2 more
core +2 more sources
Indian Journal of Endocrinology and Metabolism, 2012 We present here a case of 17-year-old boy from Kolkata presenting with obesity, bilateral gynecomastia, mental retardation, and hypogonadotrophic hypogonadism. The patient weighed 70 kg and was of 153 cm height. Facial asymmetry (unilateral facial palsy),
Semanti Chakraborty, Jayanta Chakraborty
doaj +1 more source
Transdermal delivery of testosterone [PDF]
, 2015 Male hypogonadism has been treated with exogenous testosterone since the 1930s. The early transdermal patches of testosterone became available in the 1980s with gel and solution preparations following subsequent decades.
Hadgraft, J, Lane, ME
core +1 more source
A randomised comparison evaluating changes in bone mineral density in advanced prostate cancer: luteinising hormone-releasing hormone agonists versus transdermal oestradiol [PDF]
, 2016 Background Luteinising hormone-releasing hormone agonists (LHRHa), used as androgen deprivation therapy (ADT) in prostate cancer (PCa) management, reduce serum oestradiol as well as testosterone, causing bone mineral density (BMD) loss.
Abel, Paul D. +15 more
core +6 more sources
Hormonal Factors Moderate the Associations Between Vascular Risk Factors and White Matter Hyperintensities [PDF]
arXiv, 2022 Objective: To examine the moderation effects of hormonal factors on the associations between vascular risk factors and white matter hyperintensities (WMH) in men and women, separately. Methods: WMH were automatically segmented and quantified in the UK Biobank dataset (N = 18,294). Generalised linear models were applied to examine 1) the main effects of
arxiv
Profiling of FSHR Negative Allosteric Modulators on LH/CGR Reveals Biased Antagonism with Implications in Steroidogenesis [PDF]
Molecular and Cellular Endocrinology, 436:10--22 (2016), 2018 Biased signaling has recently emerged as an interesting mean to modulate the function of many G protein-coupled receptors (GPCRs). Previous studies reported two negative allosteric modulators (NAMs) of follicle-stimulating hormone receptor (FSHR), ADX68692 and ADX68693, with differential effects on FSHR-mediated steroidogenesis and ovulation.
arxiv +1 more source
Social environment affects acquisition and color of structural nuptial plumage in a sexually dimorphic tropical passerine [PDF]
, 2012 Structural colors result from the physical interaction of light with organic materials of differing refractive indexes organized at nanoscale dimensions to produce significant interference effects.
Brasileiro, Luiza +3 more
core +17 more sources
Cogent Medicine, 2017 This study was intended to evaluate the hair growth activity of Zataria multiflora Boiss. (ZM) and Matricaria chamomilla (MC) for androgenetic alopecia following a six-month clinical trial.
Anoosheh Sharifan +2 more
doaj +1 more source