Results 91 to 100 of about 216,038 (323)

The Optimal Indication for Testosterone Replacement Therapy in Late Onset Hypogonadism

Journal of Clinical Medicine, 2019
The use of testosterone replacement therapy (TRT) for late-onset hypogonadism (LOH) is increasing every year; however, the literature shows that many men are using testosterone (T) without a clear indication. Previous studies have estimated that up to 25%
Y. Shin, J. K. Park
semanticscholar   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

Update on male reproductive endocrinology. [PDF]

, 2018
Practitioners of male reproductive and sexual medicine must have an intimate understanding of the physiology of male reproductive endocrinology, as such a knowledge is the cornerstone on which hormonal treatments are based.
Clavijo, Raul, Hsiao, Wayland
core   +1 more source

Changes in left ventricular repolarization after short-term testosterone replacement therapy in hypogonadal males

Journal of Endocrinological Investigation, 2019
Background and aimEvidences suggest that androgen deficiency is associated with sudden cardiac death (SCD). Our purpose was to analyse some electrocardiographic (ECG) markers of repolarization phase in hypogonadal patients either at baseline or after ...
G. Piccirillo, F. Moscucci, R. Pofi, G. D’Alessandro, M. Minnetti, A. Isidori, D. Francomano, Andrea Lenzi, Paolo-Emilio Puddu, Paolo-Emilio Puddu, Joachim Alexandre, D. Magrì, A. Aversa   +12 more
semanticscholar   +1 more source

Microbiome‐urothelium crosstalk in bladder cancer: From dysbiosis to clinical translation

iMetaOmics, EarlyView.
This review elucidates the critical crosstalk between the urobiome and bladder cancer (BCa), mapping the landscape from ecological dysbiosis to clinical translation. We synthesize emerging evidence on microbial signatures that distinguish BCa patients, exploring key carcinogenic mechanisms including chronic inflammation, genotoxicity, and the gut ...
Haoxiang Xu, Zhibiao Li, Lin Yang, Jun Zheng, Weijia Li, Rulin Liao, Wenxue Huang, Boyuan Sun, Zhuohang Li, Cunzhen Ma, Xunguo Yang, Zongwei Wang, Jie Zhao, Bisheng Cheng, Peng Wu   +14 more
wiley   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

The safety and efficacy of finasteride for transgender men with androgenetic alopecia: a case series

Journal of Medical Case Reports
Background Testosterone replacement therapy is commonly used in transgender men for masculinization. One of the most common adverse effects of testosterone replacement therapy is androgenetic alopecia.
Yusuke Tominaga, Tomoko Kobayashi, Yuko Matsumoto, Tomoko Sako, Takatoshi Moriwake, Satoshi Horii, Takuya Sadahira, Satoshi Katayama, Takehiro Iwata, Shingo Nishimura, Kensuke Bekku, Kohei Edamura, Masami Watanabe, Motoo Araki   +13 more
doaj   +1 more source

Nuclear expression of PG-21, SRC-1, and pCREB in regions of the lumbosacral spinal cord involved in pelvic innervation in young adult and aged rats [PDF]

, 2012
In rats, ageing results in dysfunctional patterns of micturition and diminished sexual reflexes that may reflect degenerative changes within spinal circuitry.
Amandusson, Anderson, Balazs, Berkley, Blanchet, Blanco, Blok, Breedlove, Breedlove, Burke, Chambers, Chambers, Collins, Dail, Davidson, De Cesare, Dering, Dering, Eika, Ernfors, Fargo, Ferrini, Finkbeiner, Frankel, Fraser, Ghanadian, Giuliano, Goldstein, Goldstein, Gonzalez, Gray, Gréco, Hancock, Hodges, Holmes, Hsu, Johnson, Jordan, Jordan, Jordan, Kepper, Kurz, Labombarda, Leo, Leslie, Lubischer, Marson, Marson, Marson, Marson, Marson, Matsumoto, Matsumoto, Matsumoto, Matsumoto, Matsumoto, Matsumoto, Mattson, Mayr, McKenna, McKenna, McManus, Meisel, Monks, Monks, Montminy, Nadelhaft, Nadelhaft, Nadelhaft, Nicolopoulos-Stournaras, Nordeen, O'Bryant, Osborne, Papka, Papka, Papka, Papka, Papka, Purinton, Ranson, Ranson, Ranson, Ranson, Ranson, Ranson, Reichardt, Santer, Schrøder, Sengelaub, Shibata, Smith, Smith, Tan, Tang, Tobin, Ulfhake, VanderHorst, Vera, Watkins, Watson, Williams, Wu, Wu, Yaici, Yamamoto, Yan, Yang, Yang, Yaïci   +108 more
core   +1 more source

Testosterone Replacement Therapy and Risk of Favorable and Aggressive Prostate Cancer

Journal of Clinical Oncology, 2017
Purpose The association between exposure to testosterone replacement therapy (TRT) and prostate cancer risk is controversial. The objective was to examine this association through nationwide, population-based registry data.
S. Loeb, Y. Folkvaljon, J. Damber, J. Alukal, M. Lambe, P. Stattin   +5 more
semanticscholar   +1 more source