Low Testosterone in Men With Type 2 Diabetes: The Role of Estrogen Excess and Aromatase Activity
ABSTRACT Objective Low testosterone is common in men with type 2 diabetes and is associated with adverse metabolic outcomes. Our objective was to identify factors associated with low total and calculated free testosterone (CFT) in men with type 2 diabetes, with a focus on relative estrogen excess and subcutaneous adipose aromatase expression.
Nyo Nyo Z. Tun +2 more
wiley +1 more source
Combined HMG/HCG treatment in subfertile men with idiopathic normogonadotropic ogliozoospermia [PDF]
Braun, S. +3 more
core
Testosterone Replacement Therapy in Men Aged 50 and Above: A Narrative Review of Evidence-Based Benefits, Safety Considerations, and Clinical Recommendations. [PDF]
Canal de Velasco LM +2 more
europepmc +1 more source
Mitochondrial DNA Depletion Syndrome 1 (MTDPS1)—A Novel Cause of Premature Ovarian Insufficiency
We describe a woman with MNGIE due to a novel homozygous TYMP nonsense variant and propose MNGIE as the cause of her premature ovarian insufficiency—a rarely reported association—highlighting the need to consider mitochondrial disease in unexplained POI, especially in atypical, consanguineous presentations. ABSTRACT Mitochondrial DNA depletion syndrome
Michael Matheou +3 more
wiley +1 more source
Clinical Predictors of Response to Testosterone Replacement Therapy in Boys With Micropenis: A Retrospective Study Focusing on Penile Morphology and Hormonal Factors. [PDF]
Harada J +16 more
europepmc +1 more source
Single‐cell transcriptomics reveals that the human retina expresses a broad repertoire of steroid hormone biosynthesis and estrogen signalling genes. Functional validation in retinal explants shows that local estrogen synthesis is neuroprotective, preventing photoreceptor death and limiting microglial activation. Abstract Steroid hormones, particularly
Antolin Canto +6 more
wiley +1 more source
Testosterone Replacement Therapy in Hypogonadal Men with a Prostate Cancer Diagnosis: A British Society for Sexual Medicine Consensus Statement. [PDF]
Edison MA, Kirby M, Hackett GI.
europepmc +1 more source
Abstract Menopause is the time when a woman transitions from the reproductive stage of life to the non‐reproductive state. It is characterised by significant hormonal changes, which can affect a woman's physical, emotional, mental and social well‐being.
Irene Bretón Lesmes +7 more
wiley +1 more source
Testosterone Replacement Therapy Is Not Associated with Greater Revision Rates in Reverse Total Shoulder Arthroplasty. [PDF]
Parmar RP +5 more
europepmc +1 more source
Clinical Oncological Tolerance of Testosterone Replacement Therapy Over Two Years Among Patients With High-Risk or Very High-Risk Prostate Cancer Undergoing Radiotherapy. [PDF]
Shigehara K +8 more
europepmc +1 more source

