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A Molecular Basis for Antibody Specificity Crystal Structures of IgE-Allergen and IgG-Hapten Complexes [PDF]

Niemi, Merja
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Longitudinal Improvements in Quality of Life Following Testosterone Replacement Therapy in Men with Biochemical and Symptomatic Testosterone Deficiency: a 12 Month Retrospective Observational Study in a Remote Digital Healthcare Setting in the United Kingdom

Johnson H, Clift A, Huang D, Foster J, El-Osta A.   +4 more
europepmc   +1 more source

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Cardiovascular Safety of Testosterone-Replacement Therapy.

New England Journal of Medicine, 2023
BACKGROUND The cardiovascular safety of testosterone-replacement therapy in middle-aged and older men with hypogonadism has not been determined. METHODS In a multicenter, randomized, double-blind, placebo-controlled, noninferiority trial, we enrolled ...
A. Lincoff, S. Bhasin, P. Flevaris, Lisa Mitchell, S. Basaria, W. Boden, G. Cunningham, C. Granger, M. Khera, Ian M Thompson, Qiuqing Wang, K. Wolski, Deborah A Davey, V. Kalahasti, Nader Khan, Michael G. Miller, M. Snabes, A. Chan, E. Dubcenco, Xue Li, Tingting Yi, Bidan Huang, K. Pencina, T. Travison, S. Nissen   +24 more
semanticscholar   +8 more sources

Testosterone replacement therapy: clinical considerations

Expert Opinion on Pharmacotherapy
Introduction As an increasingly popular therapeutic option, testosterone replacement therapy (TRT) has gained significant notoriety for its health benefits in indicated populations, such as those suffering from hypogonadism.
Patrick M. Luther, Noah J. Spillers, Norris C Talbot, Evan S Sinnathamby, Dakota Ellison, Rucha Kelkar, S. Ahmadzadeh, Sahar Shekoohi, A. Kaye   +8 more
semanticscholar   +3 more sources

Testosterone Replacement Therapy for Sexual Symptoms.

Sexual Medicine Reviews, 2019
BACKGROUND Several data have clearly shown that the endocrine system-and androgens in particular-play a pivotal role in regulating all the steps involved in the male sexual response cycle.
G. Rastrelli, F. Guaraldi, Yacov Reismann, A. Sforza, A. Isidori, M. Maggi, G. Corona   +6 more
semanticscholar   +5 more sources

Testosterone replacement therapy and cardiovascular disease

International Journal of Impotence Research, 2022
The use of testosterone therapy has a complex history of apprehension and questions regarding its safety. Despite an eventual consensus that testosterone therapy was safe and effective, several studies relating to cardiovascular risks emerged in the last decade, rekindling skepticism regarding the safety of testosterone therapy.
J. Auerbach, M. Khera
semanticscholar   +3 more sources

[Testosterone replacement therapy and cardiovascular risk].

Giornale italiano di cardiologia (2006), 2017
Late onset hypogonadism (LOH) is the most commonly used term to indicate the age-dependent reduction of testosterone. Sexual dysfunction represents the most important determinant for medical consultation and the most specific symptoms associated with LOH.
G. Corona, M. Dicuio, G. Rastrelli, A. Sforza, M. Maggi   +4 more
semanticscholar   +4 more sources