Results 261 to 270 of about 216,038 (323)

Cardiovascular Safety of Testosterone-Replacement Therapy.

New England Journal of Medicine, 2023
BACKGROUND The cardiovascular safety of testosterone-replacement therapy in middle-aged and older men with hypogonadism has not been determined. METHODS In a multicenter, randomized, double-blind, placebo-controlled, noninferiority trial, we enrolled ...
A. Lincoff, S. Bhasin, P. Flevaris, Lisa Mitchell, S. Basaria, W. Boden, G. Cunningham, C. Granger, M. Khera, Ian M Thompson, Qiuqing Wang, K. Wolski, Deborah A Davey, V. Kalahasti, Nader Khan, Michael G. Miller, M. Snabes, A. Chan, E. Dubcenco, Xue Li, Tingting Yi, Bidan Huang, K. Pencina, T. Travison, S. Nissen   +24 more
semanticscholar   +8 more sources

Testosterone replacement therapy: clinical considerations

Expert Opinion on Pharmacotherapy
Introduction As an increasingly popular therapeutic option, testosterone replacement therapy (TRT) has gained significant notoriety for its health benefits in indicated populations, such as those suffering from hypogonadism.
Patrick M. Luther, Noah J. Spillers, Norris C Talbot, Evan S Sinnathamby, Dakota Ellison, Rucha Kelkar, Shahab Ahmadzadeh, Sahar Shekoohi, A. Kaye   +8 more
semanticscholar   +3 more sources

Testosterone replacement therapy and erectile dysfunction

International Journal of Impotence Research, 2022
Testosterone (T) deficiency and erectile dysfunction (ED) are independently functionally and socially impairing, and their concurrence in men can be challenging to treat. Successful management requires an understanding of the mechanisms through which T underlies normal erectile function. While the literature elucidating some of these mechanisms is vast
Ifeanyi C. Onyeji, R. Clavijo
semanticscholar   +3 more sources

Testosterone replacement therapy and cardiovascular disease

International Journal of Impotence Research, 2022
The use of testosterone therapy has a complex history of apprehension and questions regarding its safety. Despite an eventual consensus that testosterone therapy was safe and effective, several studies relating to cardiovascular risks emerged in the last decade, rekindling skepticism regarding the safety of testosterone therapy.
J. Auerbach, M. Khera
semanticscholar   +3 more sources

Testosterone replacement therapy and cardiovascular risk

Nature Reviews Cardiology, 2019
Testosterone is the main male sex hormone and is essential for the maintenance of male secondary sexual characteristics and fertility. Androgen deficiency in young men owing to organic disease of the hypothalamus, pituitary gland or testes has been treated with testosterone replacement for decades without reports of increased cardiovascular events.
T. Gagliano-Jucá, S. Basaria
semanticscholar   +3 more sources

Testosterone Replacement Therapy

Archives of Andrology, 1998
The benefits conferred by testosterone replacement therapy are substantial, both in the short term for the eradication of symptoms of androgen deficiency, and in the long term for the prevention of osteoporosis. As with any long-term treatment there are risks that must be considered, but overall the benefits achieved far outweigh potential risk ...
E, Velázquez, G, Bellabarba Arata
openaire   +2 more sources

WHICH TESTOSTERONE REPLACEMENT THERAPY?

Clinical Endocrinology, 1984
SUMMARYThree different forms of testosterone (T) replacement therapy were compared; they were the intramuscular injection of mixed testosterone esters 250 mg; the subcutaneous implantation of 6 x 100 mg pellets of fused testosterone; and the oral administration of testosterone undecanoate (TU) 80 mg twice daily.
J A, Cantrill, P, Dewis, D M, Large, M, Newman, D C, Anderson   +4 more
openaire   +2 more sources

Testosterone Replacement Therapy for Sexual Symptoms.

Sexual Medicine Reviews, 2019
Several data have clearly shown that the endocrine system-and androgens in particular-play a pivotal role in regulating all the steps involved in the male sexual response cycle. Accordingly, testosterone (T) replacement therapy (TRT) represents a cornerstone of pharmacologic management of hypogonadal subjects with erectile dysfunction.The aim of this ...
G. Rastrelli, F. Guaraldi, Yacov Reismann, A. Sforza, A. Isidori, M. Maggi, G. Corona   +6 more
semanticscholar   +5 more sources

Testosterone replacement therapy reduces biochemical recurrence after radical prostatectomy

BJU International, 2020
To evaluate risk of prostate cancer biochemical recurrence (BCR) after radical prostatectomy (RP) in men receiving vs not receiving testosterone replacement therapy (TRT).
T. Ahlering, Linda My Huynh, M. Towe, K. See, J. Tran, K. Osann, F. el Khatib, F. Yafi   +7 more
semanticscholar   +1 more source