Results 261 to 270 of about 236,531 (317)

Testosterone replacement therapy and cardiovascular risk

Nature Reviews Cardiology, 2019
Testosterone is the main male sex hormone and is essential for the maintenance of male secondary sexual characteristics and fertility. Androgen deficiency in young men owing to organic disease of the hypothalamus, pituitary gland or testes has been treated with testosterone replacement for decades without reports of increased cardiovascular events.
Thiago Gagliano-Jucá, S. Basaria
semanticscholar   +3 more sources

Testosterone Replacement Therapy

Archives of Andrology, 1998
The benefits conferred by testosterone replacement therapy are substantial, both in the short term for the eradication of symptoms of androgen deficiency, and in the long term for the prevention of osteoporosis. As with any long-term treatment there are risks that must be considered, but overall the benefits achieved far outweigh potential risk ...
E, Velázquez, G, Bellabarba Arata
openaire   +2 more sources

WHICH TESTOSTERONE REPLACEMENT THERAPY?

Clinical Endocrinology, 1984
SUMMARYThree different forms of testosterone (T) replacement therapy were compared; they were the intramuscular injection of mixed testosterone esters 250 mg; the subcutaneous implantation of 6 x 100 mg pellets of fused testosterone; and the oral administration of testosterone undecanoate (TU) 80 mg twice daily.
J A, Cantrill, P, Dewis, D M, Large, M, Newman, D C, Anderson   +4 more
openaire   +2 more sources

Testosterone replacement therapy and erectile dysfunction

International Journal of Impotence Research, 2022
Testosterone (T) deficiency and erectile dysfunction (ED) are independently functionally and socially impairing, and their concurrence in men can be challenging to treat. Successful management requires an understanding of the mechanisms through which T underlies normal erectile function. While the literature elucidating some of these mechanisms is vast
Ifeanyi C. Onyeji, Raul I. Clavijo
openaire   +2 more sources

Testosterone replacement therapy reduces biochemical recurrence after radical prostatectomy

BJU International, 2020
To evaluate risk of prostate cancer biochemical recurrence (BCR) after radical prostatectomy (RP) in men receiving vs not receiving testosterone replacement therapy (TRT).
T. Ahlering, Linda My Huynh, M. Towe, K. See, J. Tran, K. Osann, F. el Khatib, F. Yafi   +7 more
semanticscholar   +1 more source

Testosterone replacement therapy

British Journal of Hospital Medicine, 2007
Hypgonadism has important adverse effects on the health and quality of life of affected men, but remains underdiagnosed in clinical practice. This article reviews the physiology, causes and diagnosis of hypogonadism and the potential benefits of treatment with testosterone replacement therapy
openaire   +2 more sources

Association between testosterone replacement therapy and cardiovascular outcomes: A meta-analysis of 30 randomized controlled trials.

Progress in cardiovascular diseases
BACKGROUND The Cardiovascular safety of testosterone replacement therapy (TRT) among men with hypogonadism is not well established to date. Hence, we sought to evaluate the cardiovascular disease (CVD) outcomes among patients receiving testosterone ...
Vikash Jaiswal, A. Sawhney, C. Nebuwa, Vamsikalyan Borra, Novonil Deb, Anupam Halder, K. Rajak, Mayank Jha, Z. Wajid, Rosy Thachil, Dhrubajyoti Bandyopadhyay, J. Mattumpuram, Carl J. Lavie   +12 more
semanticscholar   +1 more source

Testosterone replacement therapy

Medicine, 2009
Abstract Testosterone replacement therapy is a well-tolerated and established treatment for hypogonadism, providing excellent clinical and biochemical relief from the effects of sex steroid deficiency. This review gives a practical clinical guide to managing testosterone replacement therapy.
openaire   +1 more source

Pharmacogenetics of Testosterone Replacement Therapy

Pharmacogenomics, 2009
Variable phenotypes of androgen insensitivity exist in humans, mainly owing to defective, mutated androgen receptors. A more subtle modulation of androgen effects is related to the CAG repeat polymorphism ([CAG]n) in exon 1 of the androgen receptor gene, in vitro, transcription of androgen-dependent target genes is attenuated with increasing length of ...
openaire   +2 more sources

Cardiovascular and Cerebrovascular Safety of Testosterone Replacement Therapy Among Aging Men with Low Testosterone Levels: A Cohort Study.

American Journal of Medicine, 2019
PURPOSE We assessed the risk of ischemic stroke, transient ischemic attack, and myocardial infarction associated with testosterone replacement therapy (TRT) among aging men with low testosterone levels.
Simone Y Loo, L. Azoulay, Ruizhi Nie, S. Dell’Aniello, O. Yu, C. Renoux   +5 more
semanticscholar   +1 more source