Tigecycline resistance tet(X3) gene is going wild
The emergence of mobile Tigecycline-resistant tet(X3) and tet(X4) is believed to be a global threat to public health. Here, we investigated the prevalence of tet(X3) and tet(X4) in our metagenomic data of migratory birds. While tet(X4) was not identified
Jian Cao +6 more
doaj +2 more sources
Sensitive and rapid detection of tet(X2) ~ tet(X5) by loop-mediated isothermal amplification based on visual OTG dye [PDF]
The emergence of tigecycline-resistant tet(X2/X3/X4/X5) genes poses a new threat to the efficacy of anti-infective therapy and the safety of our food and environment.
Guiling Chen +7 more
doaj +2 more sources
Bovine-Derived Acinetobacter indicus Co-Harboring Chromosomal tet(X3) and Plasmid-Located tet(X4) Isolated from Henan, China [PDF]
The coexistence of antibiotic resistance genes (ARGs), particularly those conferring resistance to last-resort antibiotics, is increasingly present in lesser-studied bacterial species.
Qing Wang +6 more
doaj +2 more sources
Chromosomal and Plasmid-Borne Tigecycline Resistance Genes tet(X3) and tet(X4) in Dairy Cows on a Chinese Farm. [PDF]
Zhang R +15 more
europepmc +3 more sources
Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations [PDF]
IntroductionThe emergence of the wide variety of novel tigecycline resistance tet(X) variants, including tet(X3), tet(X4), tet(X5), and tet(X6), has raised a serious threat to global public health and posed a significant challenge to the clinical ...
Juan Liu +22 more
doaj +2 more sources
Development of a TaqMan-based triplex qPCR assay for the simultaneous detection of Muscovy reovirus, novel duck reovirus, and Riemerella anatipestifer [PDF]
IntroductionIn duck breeding production, the incidence of infection of Riemerella anatipestifer (RA), Muscovy duck reovirus (MDRV), and novel duck reovirus (NDRV) is gradually increasing.
Zhihanlin Gan +10 more
doaj +2 more sources
Gene Therapy for Fragile X Syndrome, Challenges, and Promises. [PDF]
Supplying the functional protein product of the FMR1 gene to the brain is an attractive concept for curative treatment of Fragile X syndrome. Despite existing challenges, recent developments establish the basis for developing efficient gene therapy protocols for this condition.
Velinov M.
europepmc +2 more sources
Molecular Analysis of Tigecycline Resistance in Carbapenem-Resistant Enterobacterales (CRE) in Mthatha and Surrounding Hospitals [PDF]
Background: The emergence of carbapenem-resistant Enterobacterales is prevalent and poses a significant threat to health systems worldwide. This study aimed to conduct a molecular analysis of tigecycline resistance in 100 CRE isolates from Mthatha ...
Luyolo Vumba +2 more
doaj +2 more sources
Plasmid-borne tet(X3) and chromosome-borne tet(X6) in porcine Acinetobacter isolates
Jing Wang +7 more
doaj +2 more sources
Interorder horizontal gene transfer of tet(X3) between Acinetobacter spp. and Enterobacteriaceae. [PDF]
Xu C +6 more
europepmc +2 more sources

