Results 1 to 10 of about 5,707,439 (181)
The tigecycline resistance mechanisms in Gram-negative bacilli [PDF]
Frontiers in Cellular and Infection MicrobiologyTigecycline, hailed as a pivotal agent in combating multidrug-resistant bacterial infections, confronts obstacles posed by the emergence of resistance mechanisms in Gram-negative bacilli.
Zhiren Wang, Zhiren Wang, Henan Li
doaj +7 more sources
Molecular mechanisms of tigecycline-resistance among Enterobacterales [PDF]
Frontiers in Cellular and Infection MicrobiologyThe global emergence of antimicrobial resistance to multiple antibiotics has recently become a significant concern. Gram-negative bacteria, known for their ability to acquire mobile genetic elements such as plasmids, represent one of the most hazardous ...
Lukasz Korczak +9 more
doaj +7 more sources
Resistance mechanisms of tigecycline in Acinetobacter baumannii [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 Acinetobacter baumannii is widely distributed in nature and in hospital settings and is a common pathogen causing various infectious diseases. Currently, the drug resistance rate of A.
Chunli Sun +7 more
doaj +6 more sources
Tigecycline Resistance-Associated Mutations in the MepA Efflux Pump in Staphylococcus aureus
Microbiology Spectrum, 2023 Tigecycline is an important antibacterial drug for treating infection by clinical multidrug-resistant bacteria, and tigecycline-resistant Staphylococcus aureus (TRSA) has been increasingly reported in recent years.
Honghao Huang +6 more
doaj +3 more sources
PLoS ONE, 2015 KPC-producing Klebsiella pneumoniae isolates have emerged as important pathogens of nosocomial infections, and tigecycline is one of the antibiotics recommended for severe infections caused by KPC-producing K. pneumoniae.
Fang He +6 more
doaj +5 more sources
The first tigecycline resistant Enterococcus faecium in Norway was related to tigecycline exposure [PDF]
Journal of Global Antimicrobial Resistance, 2023 : Objectives: We describe the first tigecycline resistant enterococcal isolate in Norway and the mechanisms involved. Material and methods: The Norwegian National Advisory Unit on Detection of Antimicrobial Resistance (K-res).
Kristin Hegstad +4 more
doaj +6 more sources
International Journal of Molecular SciencesThe presence of sub-minimal inhibitory concentration (sub-MIC) antibiotics in our environment is widespread, and their ability to induce antibiotic resistance is inevitable. Acinetobacter baumannii, a pathogen known for its strong ability to acquire antibiotic resistance, has recently shown clinical resistance to the last-line antibiotic tigecycline ...
Cunwei Liu +4 more
core +4 more sources
Journal of Global Antimicrobial Resistance, 2022 : Objectives: This study investigated the underlying mechanism of the evolution of tigecycline resistance during treatment in a patient infected with Klebsiella pneumoniae harbouring blaKPC-2. Methods: A total of seven clonal K.
Wenli Liao +8 more
doaj +4 more sources
Frontiers in Microbiology, 2018 Tigecycline is one of the last resort treatments for carbapenem-resistant Klebsiella pneumoniae (CRKP) infections. Tigecycline resistance often occurs during the clinical treatment of CRKP, yet its mechanism has still not been clearly elucidated.
Xiaoxing Du +6 more
doaj +4 more sources
International Journal of Antimicrobial Agents, 2016 During the past decades, rates of multidrug-resistant (MDR) and carbapenem-resistant (CR) Enterobacteriaceae clinical isolates, mainly Klebsiella spp., Escherichia coli, Enterobacter spp., Proteus spp. and Serratia marcescens, have increased, considerably restricting effective antimicrobial treatments.
Spyros Pournaras +2 more
exaly +6 more sources