Results 11 to 20 of about 30,783 (205)
Resistance mechanisms of tigecycline in Acinetobacter baumannii
Frontiers in Cellular and Infection Microbiology, 2023 Acinetobacter baumannii is widely distributed in nature and in hospital settings and is a common pathogen causing various infectious diseases. Currently, the drug resistance rate of A.
Chunli Sun +7 more
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Induction of Tigecycline Resistance in Acinetobacter baumannii
Bio-Protocol, 2014 Multidrug resistance Acinetobacter baumannii (A. baumannii) (MDRAB) has emerged as a serious threat in hospitals in recent years. Currently, there are few antibiotics, including tigecycline, available to treat infections caused by MDRAB effectively. Both
Ming-Feng Lin, Yun-You Lin, Chung-Yu Lan
doaj +2 more sources
Journal of Infection in Developing Countries, 2021 Introduction: Tigecycline is a unique class of semi-synthetic glycylcyclines developed to treat infections caused by multidrug-resistant Klebsiella pneumoniae.
Rezvan Goodarzi +4 more
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mSystems, 2021 The newly emerged tigecycline-inactivating enzymes Tet(X3) and Tet(X4), which are associated with high-level tigecycline resistance, demonstrated significantly higher activities in comparison to that of the prototypical Tet(X) enzyme, threatening the ...
Chao-Yue Cui +13 more
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The first tigecycline resistant Enterococcus faecium in Norway was related to tigecycline exposure
Journal of Global Antimicrobial Resistance: Objectives: We describe the first tigecycline resistant enterococcal isolate in Norway and the mechanisms involved. Material and methods: The Norwegian National Advisory Unit on Detection of Antimicrobial Resistance (K-res).
Kristin Hegstad +4 more
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Frontiers in Microbiology, 2018 Tigecycline is one of the last resort treatments for carbapenem-resistant Klebsiella pneumoniae (CRKP) infections. Tigecycline resistance often occurs during the clinical treatment of CRKP, yet its mechanism has still not been clearly elucidated.
Xiaoxing Du +6 more
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PLoS ONE, 2015 KPC-producing Klebsiella pneumoniae isolates have emerged as important pathogens of nosocomial infections, and tigecycline is one of the antibiotics recommended for severe infections caused by KPC-producing K. pneumoniae.
Fang He +6 more
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Genetic Determinants of Tigecycline Resistance in Mycobacteroides abscessus. [PDF]
Antibiotics (Basel), 2022 Mycobacteroides abscessus (formerly Mycobacterium abscessus) is a clinically important, rapid-growing non-tuberculous mycobacterium notoriously known for its multidrug-resistance phenotype. The intrinsic resistance of M. abscessus towards first- and second-generation tetracyclines is mainly due to the over-expression of a tetracycline-degrading enzyme ...
Ng HF, Ngeow YF.
europepmc +4 more sources
A Novel Tigecycline Adjuvant ML-7 Reverses the Susceptibility of Tigecycline-Resistant Klebsiella pneumoniae [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 The increasing incidence of tigecycline resistance undoubtedly constitutes a serious threat to global public health. The combination therapies had become the indispensable strategy against this threat. Herein, 11 clinical tigecycline-resistant Klebsiella pneumoniae which mainly has mutations in ramR, acrR, or macB were collected for tigecycline ...
Lilan Sun +7 more
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Emergence of a tet(M) Variant Conferring Resistance to Tigecycline in Streptococcus suis
Frontiers in Veterinary Science, 2021 The aim of this study was to gain insight into the resistance determinants conferring resistance to tigecycline in Streptococcus (S.) suis and to investigate the genetic elements involved in their horizontal transfer. A total of 31 tetracycline-resistant
Rui Yu +6 more
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