Results 31 to 40 of about 5,707,439 (181)

Tigecycline Heteroresistance and Resistance Mechanism in Clinical Isolates of Acinetobacter baumannii

open access: yesMicrobiology Spectrum, 2021
Tigecycline is regarded as a last-resort treatment for multidrug-resistant Acinetobacter baumannii. However, tigecycline resistance in A. baumannii has increased worldwide. In this study, we investigated tigecycline heteroresistance in A.
Jeongwoo Jo, Kwan Soo Ko
doaj   +1 more source

High tigecycline resistance in multidrug-resistant Acinetobacter baumannii [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2007
Multidrug-resistant (MDR) Acinetobacter baumannii is increasing in our hospital and worldwide, raising the necessity of finding effective therapies. We aimed to evaluate the in vitro activity of tigecycline against MDR A. baumannii clones isolated before tigecycline was used in our institution.Eighty-two unique patient clinical isolates of multidrug ...
Shiri, Navon-Venezia   +2 more
openaire   +2 more sources

Genomic and Phenotypic Evolution of Tigecycline-Resistant Acinetobacter baumannii in Critically Ill Patients

open access: yesMicrobiology Spectrum, 2022
Acinetobacter baumannii is an important opportunistic pathogen of nosocomial infections. A. baumannii presently exhibits increasing antibiotic resistance, which poses great challenges to public health. The occurrence of tigecycline-resistant A. baumannii
Jiangang Zhang   +8 more
doaj   +1 more source

Pseudomonas Acts as a Reservoir of Novel Tigecycline Resistance Efflux Pump tmexC6D6-toprJ1b and tmexCD-toprJ Variants

open access: yesMicrobiology spectrum, 2023
Tigecycline is one of the treatment options for serious infections caused by multidrug-resistant bacteria, and tigecycline resistance has gained extensive attention.
Chengzhen Wang   +10 more
semanticscholar   +1 more source

Multiple Mechanisms of Tigecycline Resistance in Enterobacteriaceae from a Pig Farm, China

open access: yesMicrobiology Spectrum, 2021
We isolated eight tigecycline-resistant Enterobacteriaceae strains from a pig farm in Shanghai, China, including Escherichia coli (n = 1), Proteus cibarius (n = 1), and Enterobacter hormaechei (n = 6). Two of them (E. coli and P.
Jing Wang   +7 more
doaj   +1 more source

Comment on: High tigecycline resistance in multidrug-resistant Acinetobacter baumannii [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2007
1. Seaman PF, Ochs D, Day MJ. Comment on: Triclosan resistance in methicillin-resistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics. J Antimicrob Chemother 2007; doi:10.1093/jac/dkm118. 2. Bayston R, Ashraf W, Smith T.
Visanu, Thamlikitkul   +2 more
openaire   +2 more sources

Emergence of high-level colistin resistance mediated by multiple determinants, including mcr-1.1, mcr-8.2 and crrB mutations, combined with tigecycline resistance in an ST656 Klebsiella pneumoniae

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Colistin and tigecycline are usually regarded as the last resort for multidrug-resistant Klebsiella pneumoniae infection treatment. Emergence of colistin and tigecycline resistance poses a global healthcare challenge and is associated with high mortality
Yan-Fei Wang   +9 more
semanticscholar   +1 more source

Effect of ramR loss-of-function insertion on tigecycline resistance in clinical isolates of carbapenem-resistant Klebsiella pneumoniae

open access: yesJournal of Global Antimicrobial Resistance, 2020
Objectives: Tigecycline is an antibacterial agent restricted for use against carbapenem-resistant Klebsiella pneumoniae (CRKP). This study aimed to identify the tigecycline resistance mechanism in clinical CRKP isolates obtained from a 60-year-old ...
Yihan Mao   +4 more
doaj   +1 more source

Emergence of Colistin Resistance in Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae Under the Pressure of Tigecycline

open access: yesFrontiers in Microbiology, 2021
Colistin and tigecycline are the last options against carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP). Intersecting resistance determinants have been detected between these antibiotics; however, there is only limited evidence of such ...
Yawei Zhang   +7 more
doaj   +1 more source

Dissemination and prevalence of plasmid-mediated high-level tigecycline resistance gene tet (X4)

open access: yesFrontiers in Microbiology, 2022
With the large-scale use of antibiotics, antibiotic resistant bacteria (ARB) continue to rise, and antibiotic resistance genes (ARGs) are regarded as emerging environmental pollutants. The new tetracycline-class antibiotic, tigecycline is the last resort
Shaqiu Zhang   +17 more
semanticscholar   +1 more source

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