Results 11 to 20 of about 214,987 (341)

Mortality from tetanus between 1990 and 2015: findings from the global burden of disease study 2015

open access: yesBMC Public Health, 2017
Background Although preventable, tetanus still claims tens of thousands of deaths each year. The patterns and distribution of mortality from tetanus have not been well characterized.
Hmwe H. Kyu   +7 more
doaj   +2 more sources

Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in mice

open access: yesScience Translational Medicine, 2022
Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease. Tumors are poorly immunogenic and immunosuppressive, preventing T cell activation in the tumor microenvironment.
B. Selvanesan   +27 more
semanticscholar   +1 more source

Toxicology and pharmacology of botulinum and tetanus neurotoxins: an update

open access: yesArchives of Toxicology, 2022
Tetanus and botulinum neurotoxins cause the neuroparalytic syndromes of tetanus and botulism, respectively, by delivering inside different types of neurons, metalloproteases specifically cleaving the SNARE proteins that are essential for the release of ...
M. Pirazzini, C. Montecucco, O. Rossetto
semanticscholar   +1 more source

Prevalence and determinants of antenatal tetanus vaccination in Sudan: a cross-sectional analysis of the Multiple Indicator Cluster Survey

open access: yesTropical Medicine and Health, 2022
Background Tetanus vaccination is an indispensable component of the antenatal care (ANC) and is considered one of the most effective and protective measures against tetanus deaths. However, data on antenatal tetanus vaccination in Sudan are scarce.
S. Mohamed, E. Ahmed
semanticscholar   +1 more source

Progress Toward Achieving and Sustaining Maternal and Neonatal Tetanus Elimination — Worldwide, 2000–2020

open access: yesMMWR. Morbidity and mortality weekly report, 2022
Maternal and neonatal tetanus (MNT)* remains a major cause of neonatal mortality with an 80%-100% case-fatality rate among insufficiently vaccinated mothers after unhygienic deliveries, especially in low-income countries (1).
Florence A. Kanu   +4 more
semanticscholar   +1 more source

Tetanus and tetanus neurotoxin: From peripheral uptake to central nervous tissue targets

open access: yesJournal of Neurochemistry, 2021
Tetanus is a deadly but preventable disease caused by a protein neurotoxin produced by Clostridium tetani. Spores of C. tetani may contaminate a necrotic wound and germinate into a vegetative bacterium that releases a toxin, termed tetanus neurotoxin ...
A. Megighian   +4 more
semanticscholar   +1 more source

Use of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccines: Updated Recommendations of the Advisory Committee on Immunization Practices — United States, 2019

open access: yesMMWR. Morbidity and mortality weekly report, 2020
Since 2005, a single dose of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine has been recommended by the Advisory Committee on Immunization Practices (ACIP) for adolescents and adults (1,2).
F. Havers   +4 more
semanticscholar   +1 more source

Waning immunity after receipt of Pertussis, Diphtheria, Tetanus and Polio-related vaccines: a systematic review and meta-analysis.

open access: yesJournal of Infectious Diseases, 2021
DTP-containing (pertussis, diphtheria and tetanus) combined with polio vaccines are recommended by WHO as part of routine immunization programs. The decline of immunity after vaccination has been considered as a possible reason for the re-emergence of ...
Huizhi Gao, E. Lau, B. Cowling
semanticscholar   +1 more source

Tetanus in animals

open access: yesJournal of Veterinary Diagnostic Investigation, 2020
Tetanus is a neurologic disease of humans and animals characterized by spastic paralysis. Tetanus is caused by tetanus toxin (TeNT) produced by Clostridium tetani, an environmental soilborne, gram-positive, sporulating bacterium.
M. Popoff
semanticscholar   +1 more source

An Unusual Case of Chronic Relapsing Tetanus Associated with Mandibular Osteomyelitis [PDF]

open access: yes, 2009
A 55-year-old man underwent radiation therapy due to malignant lymphoma of the neck. Eight years after the therapy he developed tetanus. It appears that the radiation therapy resulted in mandibular necrosis, and that this lesion may have been the ...
Fujimuro, Masahiro   +14 more
core   +1 more source

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