Results 11 to 20 of about 129,564 (284)
Journal of Veterinary Diagnostic Investigation, 2020 Tetanus is a neurologic disease of humans and animals characterized by spastic paralysis. Tetanus is caused by tetanus toxin (TeNT) produced by Clostridium tetani, an environmental soilborne, gram-positive, sporulating bacterium. The disease most often results from wound contamination by soil containing C. tetani spores.
M. Popoff
openaire +5 more sources
Mortality from tetanus between 1990 and 2015: findings from the global burden of disease study 2015
BMC Public Health, 2017 Background Although preventable, tetanus still claims tens of thousands of deaths each year. The patterns and distribution of mortality from tetanus have not been well characterized.
Hmwe H. Kyu +7 more
doaj +2 more sources
Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in mice
Science Translational Medicine, 2022 Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease. Tumors are poorly immunogenic and immunosuppressive, preventing T cell activation in the tumor microenvironment.
B. Selvanesan +27 more
semanticscholar +1 more source
Toxicology and pharmacology of botulinum and tetanus neurotoxins: an update
Archives of Toxicology, 2022 Tetanus and botulinum neurotoxins cause the neuroparalytic syndromes of tetanus and botulism, respectively, by delivering inside different types of neurons, metalloproteases specifically cleaving the SNARE proteins that are essential for the release of ...
M. Pirazzini, C. Montecucco, O. Rossetto
semanticscholar +1 more source
Tropical Medicine and Health, 2022 Background Tetanus vaccination is an indispensable component of the antenatal care (ANC) and is considered one of the most effective and protective measures against tetanus deaths. However, data on antenatal tetanus vaccination in Sudan are scarce.
S. Mohamed, E. Ahmed
semanticscholar +1 more source
Tetanus and tetanus neurotoxin: From peripheral uptake to central nervous tissue targets
Journal of Neurochemistry, 2021 Tetanus is a deadly but preventable disease caused by a protein neurotoxin produced by Clostridium tetani. Spores of C. tetani may contaminate a necrotic wound and germinate into a vegetative bacterium that releases a toxin, termed tetanus neurotoxin ...
A. Megighian +4 more
semanticscholar +1 more source
Journal of Infectious Diseases, 2021 DTP-containing (pertussis, diphtheria and tetanus) combined with polio vaccines are recommended by WHO as part of routine immunization programs. The decline of immunity after vaccination has been considered as a possible reason for the re-emergence of ...
Huizhi Gao, E. Lau, B. Cowling
semanticscholar +1 more source
MMWR. Morbidity and mortality weekly report, 2020 Since 2005, a single dose of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine has been recommended by the Advisory Committee on Immunization Practices (ACIP) for adolescents and adults (1,2).
F. Havers +4 more
semanticscholar +1 more source
BioMed Research International, 2020 Background Maternal tetanus is defined as tetanus acquired during pregnancy or within 6 weeks after the end of conception. As tetanus is a vaccine-preventable disease, immunization of pregnant mothers with a TT (tetanus toxoid) dose is one of the most ...
T. Gebremedhin +4 more
semanticscholar +1 more source
Progress Toward Maternal and Neonatal Tetanus Elimination — Worldwide, 2000–2018
MMWR. Morbidity and mortality weekly report, 2020 Maternal and neonatal tetanus* (MNT) remains a major public health problem, with an 80%-100% case-fatality rate among neonates, especially in areas with poor immunization coverage and limited access to clean deliveries (i.e., delivery in a health ...
H. Njuguna +4 more
semanticscholar +1 more source