Results 51 to 60 of about 129,564 (284)
Epidemiological trends of tetanus from East Delhi, India: A hospital-based study
Journal of Infection and Public Health, 2014 Objective: To study the demographic profile, prognostic indicators, and mortality of tetanus patients and treatment outcomes following intramuscular anti-tetanus immunoglobulin (ATG) alone or combined intrathecal and intramuscular ATG.
Manish Narang +3 more
doaj +1 more source
npj Vaccines, 2017 Monoclonal antibodies are widely used to treat non-infectious conditions but are costly. Vaccines could offer a cost-effective alternative but have been limited by sub-optimal T-cell stimulation and/or weak vaccine responses in recipients, for example ...
A. Zeltiņš +13 more
semanticscholar +1 more source
Advanced Intelligent Systems, EarlyView.A six‐element viscoelastic model is presented for tissue‐engineered skeletal muscle, addressing the limitations of the conventional Hill's model. By introducing an active branch, the model accurately describes force responses in both elongation and isometric tests and successfully predicts the electrically induced displacement of a reverse‐action ...
Mizuki Nakamura +6 more
wiley +1 more source
Neonatal tetanus in St. Mary’s Hospital Lacor: A case report
Clinical Case Reports, 2020 Umbilical stump sepsis in a nonpassively immunized neonate poses a high risk to neonatal tetanus. Management of neonatal tetanus is still a great challenge in resource‐limited settings where some health facilities lack tetanus toxoid containing vaccines,
Ronald Okidi +2 more
doaj +1 more source
The structure of the tetanus toxin reveals pH‐mediated domain dynamics
EMBO Reports, 2017 The tetanus neurotoxin (TeNT) is a highly potent toxin produced by Clostridium tetani that inhibits neurotransmission of inhibitory interneurons, causing spastic paralysis in the tetanus disease. TeNT differs from the other clostridial neurotoxins by its
G. Masuyer, J. Conrad, P. Stenmark
semanticscholar +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Novel compounds targeting the adaptive immune system are commonly initially investigated in healthy volunteers (HV). HV frequently lack constitutively expressed drug‐target engagement biomarkers, complicating the evaluation of pharmacological activity. The keyhole limpet hemocyanin (KLH) neo‐antigen challenge elicits a controlled immune response in HV ...
Micha N. Ronner +10 more
wiley +1 more source
BMC Pregnancy and Childbirth, 2018 BackgroundGlobally, tetanus toxoid protective dose immunization of the mothers is one of the strategies of maternal and neonatal tetanus prevention. Ethiopia has planned the national tetanus protection at birth coverage to reach 86% by the year 2015 ...
Muhabaw Shumye Mihret +2 more
semanticscholar +1 more source
Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Epilepsia Open, EarlyView.Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source
مجله دانشگاه علوم پزشکی بیرجند, 2022 Tetanus is a neurological disease associated with increased muscle contraction and spasm in patients. The risk and progression of the disease are higher in elderly patients.
Habiballah Ebrahimzade +6 more
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