Results 51 to 60 of about 4,667 (166)

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

Age-Related Dynamics in Post-Vaccine Antibody Immune Response to Diphtheria and Tetanus Toxoid in Bulgarian Subjects

Acta Medica Bulgarica, 2021
In this study, we investigated the age-related dynamics in post-vaccine humoral immunity to diphtheria (DT) and tetanus (TT) toxoids in the Bulgarian population.
Lesichkova S., Mihailova S., Mihaylova A., Gesheva N., Yankova P., Naumova E.   +5 more
doaj   +1 more source

Botulinum Neurotoxins: History, Mechanism, and Applications. A Narrative Review

Journal of Neurochemistry, Volume 169, Issue 8, August 2025.
Botulinum neurotoxins (BoNTs), produced by Clostridium botulinum, bind irreversibly to presynaptic cholinergic nerve terminals and exploit a zinc‐dependent mechanism to cleave SNARE proteins, blocking acetylcholine release and causing flaccid paralysis.
Arik Monash, Joseph Tam, Osnat Rosen, Hermona Soreq   +3 more
wiley   +1 more source

Determination of low tetanus or diphtheria antitoxin titers in sera by a toxin neutralization assay and a modified toxin-binding inhibition test

Brazilian Journal of Medical and Biological Research, 2007
A method for the screening of tetanus and diphtheria antibodies in serum using anatoxin (inactivated toxin) instead of toxin was developed as an alternative to the in vivo toxin neutralization assay based on the toxin-binding inhibition test (TOBI test).
M.H. Sonobe, A.G. Trezena, F.B. Guilhen, V.L. Takano, F. Fratelli, D. Sakauchi, J.F. Morais, S.M.A. Prado, H.G. Higashi   +8 more
doaj  

Adrenaline Auto‐Injectors for Preventing Fatal Anaphylaxis

Clinical &Experimental Allergy, Volume 55, Issue 1, Page 19-35, January 2025.
During 35 years of increasing Adrenaline Autoinjector prescribing, there has been no obvious reduction in numbers of fatal anaphylaxis cases. Animal and human studies suggest intravenous adrenaline infusion, with appropriate fluid resuscitation, prevents fatal anaphylaxis.
Marcus Sim, Vibha Sharma, Karen Li, Mary Hazel Gowland, Tomaz Garcez, Cassandra Shilladay, Richard Pumphrey, Nandinee Patel, Paul J. Turner, Robert J. Boyle   +9 more
wiley   +1 more source

Tetanus immunity in 50 Years of Age and Older Persons in Kashan

Sālmand, 2011
Ojectives: Tetanus is a neurologic disorder which occurs as sporadic cases in people with incomplete vaccination course.The most tetanus patients are people over 60 years of age.It is a important disease in elderly patients because of risk of severe ...
Reza Razaghi, Ahmad Khalife Soltani, Mansoureh Momen Heravi   +2 more
doaj  

The challenges and breakthroughs in the development of diagnostic monoclonal antibodies

VIEW, Volume 5, Issue 4, August 2024.
This study has systematically organized the discovery of antibodies into three stages and analyzed the advantages and disadvantages of each stage. Meanwhile, This study deeply analyzes challenges, proposing innovative strategies for the next generation of diagnostic antibody development. Aimed at moving closer to the gold standard of antibody discovery,
Jing Wang, Qitao Song, Tao Yang, Yuanli Li, Lihua Zhang, Jiayan Li, Feifei Liu, Yanyin Lin, Xiaoxia Xu, Yu Heng, Lulai Xu, Shun Zhang, Jiahui Zhou, Yunbo Liu, Lingyuan Kong, Dingbin Tang, Chengdong Ji, Bing Tan, Pu Liao, Nengke Pan, Weijing Yi, Zhanhui Wang   +21 more
wiley   +1 more source

Subclinical infection and potential shedding routes of equine parvovirus‐hepatitis among hospitalized horses in Austria

Journal of Veterinary Internal Medicine, Volume 38, Issue 4, Page 2373-2379, July/August 2024.
Abstract Background Equine parvovirus hepatitis (EqPV‐H) can cause Theiler's disease and subclinical hepatitis in horses. Objectives Assess the frequency of subclinical EqPV‐H infection in hospitalized horses and to study viral transmission by investigating potential shedding routes.
Dilara Lale, Esther E. Dirks, Irina Preining, Manolis Lyrakis, Andre Gömer, Eike Steinmann, Jessika‐M. V. Cavalleri, Anna Sophie Ramsauer   +7 more
wiley   +1 more source

Risk factors and preventive role of vaccination in adult tetanus fatality: a systematic review of reported cases (1990-2024) and meta-analysis

International Journal of Infectious Diseases
Objectives: This study identifies key risk factors for fatality among adult tetanus patients, assesses the impact of vaccination status and antibody levels on disease severity and outcomes in tetanus cases.
Selin Kolsuz, Deniz Güllü, Koçer Dilan Karahan, Önder Ergönül   +3 more
doaj   +1 more source

What is the role of microbial biotechnology and genetic engineering in medicine?

MicrobiologyOpen, Volume 13, Issue 2, April 2024.
Microbial biotechnology, the technological application of microorganisms, has been instrumental in producing significant natural bioactive products. These include antibiotics, antifungals, anticancer drugs, antiparasitics, antivirals, immunosuppressants, toxoid vaccines, and therapeutic enzymes.
Fernando Santos‐Beneit
wiley   +1 more source