Results 111 to 120 of about 328,500 (323)

Severity Detection Tool for Patients with Infectious Disease [PDF]

open access: yesarXiv, 2019
Hand, foot and mouth disease (HFMD) and tetanus are serious infectious diseases in low and middle income countries. Tetanus in particular has a high mortality rate and its treatment is resource-demanding. Furthermore, HFMD often affects a large number of infants and young children.
arxiv  

Preparation of Tetanus toxoid for equine

open access: yesJournal of Veterinary Medical Research, 2010
Tetanus toxoid for equines has been prepared by cultivation of C. tetani into new synthetic medium for production of high potent tetanus toxin which gave high flocculation units [90 Lf (Limit of flocculation)], and high minimum lethal dose (MLD) (600,000)
H. A. EL-Helw   +2 more
doaj  

Tetanus Toxin Is Transported in a Novel Neuronal Compartment Characterized by a Specialized pH Regulation*

open access: yesJournal of Biological Chemistry, 2005
Tetanus toxin binds specifically to motor neurons at the neuromuscular junction. There, it is internalized into vesicular carriers undergoing fast retrograde transport to the spinal cord.
S. Bohnert, G. Schiavo
semanticscholar   +1 more source

Therapeutic Potential of Lipid Nanoparticle‐Encapsulated CD19‐Targeting mRNAs in Lupus and Rheumatoid Arthritis

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo   +10 more
wiley   +1 more source

A Targeted Therapeutic Rescues Botulinum Toxin-A Poisoned Neurons [PDF]

open access: yes, 2008
Botulinum neurotoxin (BoNT), a Category A biothreat agent, is the most potent poison known to mankind. Currently no antidote is available to rescue poisoned synapses.
Bal Ram Singh   +6 more
core   +1 more source

Severe pertussis infection in infants less than 6 months of age: clinical manifestations and molecular characterization [PDF]

open access: yes, 2017
We conducted a study to determine the main traits of pertussis among unimmunized infants less than 6 months of age. From August 2012 to March 2015, 141 nasopharyngeal aspirates (NPAs) were collected from infants with respiratory symptoms attending 2
Buttinelli, Gabriele   +12 more
core   +1 more source

Echis carinatus Snakebite, a Rare Fatal Envenomation Incident in a Young Pakistani Boy: Case Report

open access: yesClinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Prompt identification and aggressive intervention in Echis carinatus envenomation are paramount to avert life‐threatening complications such as venom‐induced consumptive coagulopathy (VICC), acute renal failure (ARF), and necrotizing fasciitis.
Farina Fatima Siddiqui   +8 more
wiley   +1 more source

Toxin-allelopathy among phytoplankton species prevents competitive exclusion [PDF]

open access: yesJournal of Biological Systems, 2006, 2006
Toxic or allelopathic compounds liberated by toxin-producing phytoplankton (TPP) acts as a strong mediator in plankton dynamics. On an analysis of a set of phytoplankton biomass-data that have been collected by our group in the North-West part of the Bay of Bengal, and by analysis of a three-component mathematical model under a constant as well as a ...
arxiv  

In Silico Modeling and Production of New Vaccine Consisting of E7 Antigen Conjugated with Tetanus Toxin

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017
BACKGROUND AND OBJECTIVE: The cervical cancer is one of the main causes of death in women. Human Papilloma Virus (HPV) has been isolated in more than 98% of cervical cancer cases. The E7 has low capacity for induction immune response.
M Jokar   +5 more
doaj  

Thermic dehorning and ear tagging as atypical portals of entry of Clostridium tetani in ruminants [PDF]

open access: yes, 2011
This paper describes two infections with Clostridium tetani (C. tetani). One outbreak occurred after dehorning of calves, the second infection happened after ear tagging of a goat.
Boyen, Filip   +6 more
core   +1 more source

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