Results 31 to 40 of about 16,622 (148)

The absence of iron deficiency effect on the humoral immune response of piglets to tetanus toxoid

Veterinární Medicína, 2007
The aim of this study was to investigate an antibody response to tetanus toxoid in iron-deficient piglets. Ten piglets were not given any iron preparation until the age of 21 days.
M. Svoboda, K. Nechvatalova, J. Krejci, J. Drabek, R. Ficek, M. Faldyna   +5 more
doaj   +1 more source

Protective doses of tetanus toxoid immunization and its associated factors among mothers in southern Ethiopia

Human Vaccines & Immunotherapeutics
The World Health Organization recommends tetanus toxoid immunization before or during pregnancy for all women of childbearing age. The goal is to reduce maternal and neonatal mortality due to tetanus. According to the 2016 Ethiopia Demographic and Health
Maycas Gembe, Teklu Wosenyeleh, Wubishet Gezimu   +2 more
doaj   +1 more source

Predictors of Neonatal Tetanus Mortality in Katsina State, Northwestern Nigeria

Health Services Research & Managerial Epidemiology, 2017
Background: The mortality rate of neonatal tetanus (NNT) remains high in Nigeria. The study was guided by Mosley and Chen’s model for the elements of child survival in developing countries.
Shafique Sani Nass, Hadi Danawi, Loretta Cain, Manoj Sharma   +3 more
doaj   +1 more source

Safety and Immunogenicity of a Recombinant Tetanus Vaccine in Healthy Adults in China: A Randomized, Double‐Blind, Dose Escalation, Placebo‐ and Positive‐Controlled, Phase 1/2 Trial

Advanced Science, 2021
Tetanus is a fatal but vaccine‐preventable disease. The currently available tetanus vaccines are tetanus toxoid (TT)‐based. Although these vaccines are generally effective, challenges in vaccine development and access remain.
Xiaowei Xu, Rui Yu, Lanlan Xiao, Jie Wang, Meihong Yu, Junjie Xu, Yajun Tan, Xiao Ma, Xiaoxin Wu, Jiangshan Lian, Kaizhou Huang, Xiaoxi Ouyang, Sheng Bi, Shipo Wu, Xiaoyan Wang, Jiandi Jin, Ling Yu, Huafen Zhang, Qi Wei, Jinfa Shi, Wei Chen, Lanjuan Li   +21 more
doaj   +1 more source

Tetanus Toxin Fragment C: Structure, Drug Discovery Research and Production

Pharmaceuticals, 2022
Tetanus toxoid (TTd) plays an important role in the pharmaceutical world, especially in vaccines. The toxoid is obtained after formaldehyde treatment of the tetanus toxin. In parallel, current emphasis in the drug discovery field is put on producing well-
Caroline Bayart, Angélique Mularoni, Nada Hemmani, Soumeya Kerachni, Joachim Jose, Patrice Gouet, Joseph Paladino, Marc Le Borgne   +7 more
doaj   +1 more source

Trends in neonatal and post-neonatal tetanus admissions at a Nigerian teaching hospital

Journal of Infection in Developing Countries, 2012
Introduction: Tetanus accounts for high morbidity and case fatality rates in developing countries. This study therefore aimed to identify reasons for the persistence of this disease.
Olusola Adetunji Oyedeji, Francis Fadero, Victor Joel-Medewase, Peter Elemile, Gabriel Ademola Oyedeji   +4 more
doaj   +1 more source

Decline of serologic immunity to diphtheria, tetanus and pertussis with age suggested a full life vaccination in mainland China

Human Vaccines & Immunotherapeutics, 2021
Background: Diphtheria-tetanus-pertussis (DTP) vaccine has already been involved in national vaccination program for several decades in China. The immunity against these diseases in the people of all ages is not well investigated.
Dandan Liu, Xiaoping Cheng, Shi Wei, Lin Yuan, Changhui Chen, Kaihu Yao   +5 more
doaj   +1 more source

Preparation of Tetanus toxoid for equine [PDF]

Journal of Veterinary Medical Research, 2010
Tetanus toxoid for equines has been prepared by cultivation of C. tetani into new synthetic medium for production of high potent tetanus toxin which gave high flocculation units [90 Lf (Limit of flocculation)], and high minimum lethal dose (MLD) (600,000). Tetanus toxin was inactivated by formalin, and adsorbed on aluminum hydroxide gel as an adjuvant.
H. A. EL-Helw, M. M. Fayez, Roukaia M. Osman   +2 more
openaire   +3 more sources

Three cases of neonatal tetanus in Papua New Guinea lead to development of national action plan for maternal and neonatal tetanus elimination

Western Pacific Surveillance and Response, 2013
Maternal or neonatal tetanus causes deaths primarily in Asia and Africa and is usually the result of poor hygiene during delivery. In 2011, three neonatal tetanus cases were investigated in Papua New Guinea, and all three cases were delivered at home by ...
Grace Kariwiga, Steven Toikilik, Laura Guarenti, Adeline Sitther, Roland Barnabas, Siddharta Sankar Datta, Gerard Pai Sui   +6 more
doaj   +1 more source

Modeling the effects of tetanus vaccination on chronically infected HIV patients [PDF]

JAIDS (31) 369-377 (2002), 2001
T-cell activation plays a critical role in the initiation and propagation of HIV-1 infection and yet transient activation of the immune system is a normal response to immunization. In this study we extend a simple of model of HIV infection to include T cell activation by vaccination.
arxiv