Results 31 to 40 of about 38,058 (217)
Numerical study of rocket upper stage deorbiting using passive electrodynamic tether drag [PDF]
INCAS Bulletin, 2014 The purpose of this article is a numerical study of the possibility of deorbiting a rocket upper stage from low Earth orbit at EOM (end of mission) by means of passive electrodynamic tether drag.
Alexandru IONEL
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Aerospace, 2023 This paper is dedicated to identifying stable equilibrium positions of the tether systems attached to the L1 or L2 libration points of the Mars–Phobos system.
Vladimir S. Aslanov +1 more
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
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Космические аппараты и технологии, 2021 The development of space transport systems for the delivery of payloads and the study of the lunar surface is an important scientific and technical challenge.
T. A. Ledkova, Yu. M. Zabolotnov
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Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
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Mode coupling internal resonance characteristics of submerged floating tunnel tether
SN Applied Sciences, 2021 Article Highlights When the tether is only subjected to in-plane or out of plane harmonic loads, if the first-order in-plane and out of plane frequencies of tether are close to each other, the tether is prone to occur modal coupling internal resonance ...
Sheng-nan Sun, Yu-long Pan, Zhi-bin Su
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