Results 71 to 80 of about 53,538 (292)

Rational Control of Antibody Orientation for Enhancing Sensitivity and Specificity in Lateral Flow Immunoassays With Clinical Validation

Advanced Healthcare Materials, EarlyView.
Systematic investigation of antibody orientation strategies in lateral flow immunoassays reveals that a para‐substituted (aminomethyl)phenylboronic acid mediated probe (P‐6) combined with a biotin‐streptavidin test‐line modification achieves a synergistic 14‐ to 19‐fold sensitivity gain over conventional conjugation. Furthermore, multiplexed detection,
Pin‐Hao Wang, Shunmuga Nathan Shunmuga Nainar, Bing‐Han Zhuang, Shun‐Mao Yang, Hong‐Cheu Lin, Yang‐Hsiang Chan   +5 more
wiley   +1 more source

MiniCORVET is a Vps8-containing early endosomal tether in Drosophila

eLife, 2016
Yeast studies identified two heterohexameric tethering complexes, which consist of 4 shared (Vps11, Vps16, Vps18 and Vps33) and 2 specific subunits: Vps3 and Vps8 (CORVET) versus Vps39 and Vps41 (HOPS).
Péter Lőrincz, Zsolt Lakatos, Ágnes Varga, Tamás Maruzs, Zsófia Simon-Vecsei, Zsuzsanna Darula, Péter Benkő, Gábor Csordás, Mónika Lippai, István Andó, Krisztina Hegedűs, Katalin F Medzihradszky, Szabolcs Takáts, Gábor Juhász   +13 more
doaj   +1 more source

Simulation study of the plasma-brake effect [PDF]

Annales Geophysicae, 2014
Plasma brake is a thin, negatively biased tether that has been proposed as an efficient concept for deorbiting satellites and debris objects from low Earth orbit.
P. Janhunen, P. Janhunen
doaj   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

Advanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh, Peyman GhavamiNejad, Arash Khorrami Jahromi, Sanjana Srikant, Sripadh Guptha Yedire, Fatemeh Keyvani, Roozbeh Siavash Moakhar, Sajad Shiekh, Mackenzie Graham, Joe Quadrilatero, Mahla Poudineh, Sara Mahshid   +11 more
wiley   +1 more source

Thermodynamic Limits to Molecular Doping in Conjugated Polymers: A Perspective on Phase Behavior and Miscibility

Advanced Materials, EarlyView.
Molecular doping of conjugated polymers is fundamentally constrained by thermodynamic phase behavior. This Perspective reframes doping efficiency and stability in terms of miscibility limits, binodals, and solvus boundaries, highlighting the role of effective interaction parameters and charge transfer.
Somayeh Kashani, Justin Neu, Sung‐Joo Kwon, Runqio Song, Zixuan Chen, Tajah Trapier, Paschalis Gkoupidenis, David Ginger, Wei You, Jasper J. Michels, Harald Ade   +10 more
wiley   +1 more source

TRAPP Complexes in Secretion and Autophagy

Frontiers in Cell and Developmental Biology, 2016
TRAPP is a highly conserved modular multi-subunit protein complex. Originally identified as a transport protein particle with a role in endoplasmic reticulum-to-Golgi transport, its multiple subunits and their conservation from yeast to humans were ...
Jane J Kim, Zhanna eLipatova, Nava eSegev   +2 more
doaj   +1 more source

Adsorption‐Engineered Hydrocarbon Ionomers for Durable Proton‐Exchange Membrane Fuel Cells

Advanced Materials, EarlyView.
Hydrocarbon ionomers suffer from oxidation‐driven interfacial degradation in PEM fuel cell cathodes, leading to catalyst instability. Here, adsorption‐engineered poly(fluorene) ionomers decouple interfacial anchoring from oxidative degradation, enabling strong catalyst–ionomer interactions while resisting electrochemical oxidation.
Heemin Park, Kate Chen, Su Min Ahn, Hengquan Guo, Cy Fujimoto, Jong‐Ho Choi, Lynda Amichi, Danah Kim, Seung Geol Lee, Xiaojing Wang, Jacob S. Spendelow, Sun Young Kang, Panagiotis Bexis, Eun Joo S. Park, Yu Seung Kim   +14 more
wiley   +1 more source

Nuclear Pore Mechanotransduction in Oncology: A Structural Axis of Vulnerability for Targeted Intervention

Advanced Materials, EarlyView.
Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Yun Qian, Wei‐En Yuan, Victor Shahin   +5 more
wiley   +1 more source

Tether-Controlled Cycloadditions for the Asymmetric Synthesis of Decalins:  Increased Selectivity in Acetonitrile Solvent

, 2016
The beneficial influence of cis-isopropylidene acetal tether control groups, to facilitate the asymmetric synthesis of substituted decalins by intramolecular Diels−Alder reactions, is described.
Stéphanie Legoupy (2643406), Alex Melekhov (2725945), Alex G. Fallis (2305276), Pat Forgione (539102)   +3 more
core   +1 more source

A Unification of Models of Tethered Satellites [PDF]

, 2011
In this paper, different conservative models of tethered satellites are related mathematically, and it is established in what limit they may provide useful insight into the underlying dynamics.
Kristiansen, K. Uldall, Roberts, M., Roberts, M, M. Roberts, Palmer, P, K. Uldall Kristiansen, Kristiansen, KU, P. Palmer, Palmer, P.   +8 more
core   +1 more source