Results 201 to 210 of about 7,006 (230)

Intracellular Host Restriction of Hepatitis B Virus Replication. [PDF]

Viruses
Sinha P, Thio CL, Balagopal A.
europepmc   +1 more source

Decision letter: Tetherin is an exosomal tether

, 2016
openaire   +1 more source

A modified cyclosporine enhances lentivector transduction ex vivo and in vivo by degrading IFITM3

Annett D, Morling KL, Critchley BJ, Graham B, Pingitore V, Whittaker TE, Kurdi N, Warne J, León-Rico D, Kuru N, Toros S, Nurullah T, Hare A, Whelan MVX, Chan EAW, Milne RSB, Newton LS, Ali H, Powell K, Rizzi M, Thrasher AJ, Santilli G, Thorne LG, Selwood DL, Towers GJ.   +24 more
europepmc   +1 more source

Influenza virus is not restricted by tetherin whereas influenza VLP production is restricted by tetherin

Virology, 2011
Tetherin (ST2/CD317) is a cellular protein that restricts the release from cells of some enveloped viruses including HIV-1. To examine if influenza virus is affected by tetherin, MDCK cells constitutively expressing human tetherin and control MDCK cells were infected with influenza virus. No difference was observed in infectious titers, at 24 h or 48 h
Rie Watanabe
exaly   +3 more sources

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Tetherin lets HCMV in

Nature Reviews Microbiology, 2011
exaly   +2 more sources

Abstract 396: Plasticity Of The Tumor Vasculature Is Induced By Tumor Cells Via Cell Surface Receptor Tetherin

Arteriosclerosis, Thrombosis and Vascular Biology, 2023
It is increasingly clear that cardiovascular disease and cancer have shared pathophysiological mechanisms beyond traditional risk factors. Murine models have demonstrated tumors grow more quickly in the presence of cardiovascular abnormalities, and ...
Caitlin F. Bell, Sharika Bamezais, W. Ma, Nicolas G Lopez, Richard A. Baylis, Lingfeng Luo, Clint L Miller, Nick J. Leeper   +7 more
semanticscholar   +1 more source

Structural Basis of Tetherin Function

Current HIV Research, 2012
HIV-1 employs its structural proteins to orchestrate assembly and budding at the plasma membrane of host cells, which depends on numerous cellular factors. Although cells evolved interferon inducible restriction factors such as tetherin that act as a first line of defense, enveloped viruses, including HIV-1, developed countermeasures in the form of ...
Weissenhorn, Winfried, Miguet, Nolwenn, Aschman, Nick, Renesto, Patricia, Usami, Yoshiko, G. Gottlinger, Heinrich   +5 more
openaire   +3 more sources

Intracellular Logistics of BST-2/Tetherin

Current HIV Research, 2012
Bone marrow stromal antigen 2 (BST-2) is a type II membrane protein with two targeting signals, one of which is located in the cytoplasmic domain and contains a non-canonical dual tyrosine-based motif responsible for its endocytosis from the plasma membrane, and the other is a C-terminal glycosylphosphatidylinositol anchor that facilitates its ...
Hideaki, Fujita, Keiko, Fujimoto, Kenzo, Tokunaga, Yoshitaka, Tanaka   +3 more
openaire   +2 more sources

Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists [PDF]

Cell Host and Microbe, 2009
The tetherin/BST2/CD317 protein blocks the release of HIV-1 and other enveloped viruses by inducing tethering of nascent particles to infected cell surfaces. The HIV-1 Vpu protein antagonizes the antiviral activity of human but not monkey tetherins and many simian immunodeficiency viruses (SIVs) do not encode Vpu.
Jan Münch, Frank Kirchhoff, Paul D Bieniasz   +2 more
exaly   +3 more sources

Review 2: "SARS-CoV-2 spike downregulates tetherin to enhance viral spread"

, 2021
The authors investigated the possible role of the cellular protein tetherin in modulating an infection by SARS-CoV-2. The studies were based on the observation that tetherin appears to inhibit the release of a number of enveloped RNA viruses including ...
B. Milavetz
semanticscholar   +1 more source