Results 141 to 150 of about 90,627 (259)

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

Advanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang, Qiubo Chen, Shihai Lan, Liang Zhu, Shuaiyu Liu, Yan Xia, Yalu Zhang, Hanhui Yao, Yongman Liu, Shangquan Wu, Qingchuan Zhang   +10 more
wiley   +1 more source

Single‐Step Electrochemical Aptasensor for Melatonin Detection in Unprocessed Plasma

Advanced Science, EarlyView.
Melatonin is a well‐known biomarker with significant potential for clinical use in diagnosing circadian rhythm sleep disorders (CRSDs) and monitoring patients with documented circadian clock disruption. An electrochemical aptamer‐based biosensor (E‐aptasensor), employing an optimized population of melatonin aptamers, has been proposed as a solution for
Hamed Shieh, Arash Khorrami Jahromi, Fernando Gonzales‐Aste, Sajad Shiekh, Roozbeh Siavash Moakhar, Sahar Sadat Mahshid, Sara Mahshid   +6 more
wiley   +1 more source

Vertebral Body Tethering of Double Major Curvature via Mini-Open, Thoracoscopically-Assisted Thoracic and Thoracoabdominal Approaches. [PDF]

JBJS Essent Surg Tech
Lonner BS, Kurapatti M, Dolgopolov S, Youssef G, Mucollari O.   +4 more
europepmc   +1 more source

The effect of age at tethering on behaviour of heifer calves.

, 1995
The aims of the study were to investigate the behavioural consequences of tethering and to investigate the behavioural changes after tethering in calves of two different age groups.
Jensen, Margit Bak,
core  

Vascularized Perifascial Areolar Tissue-augmented Superficial Circumflex Iliac Artery Perforator Flap as an Adhesion-tolerant Functional Gliding Interface. [PDF]

Plast Reconstr Surg Glob Open
Takagi S, Hokazono T, Tamagawa K, Kojima Y, Igaki R, Miyashita T, Hamada S, Horinouchi T, Osawa A, Kadomatsu K.   +9 more
europepmc   +1 more source

Electrochemically Driven Regioselective Radical Functionalization of Allenes: Scope and Mechanistic Insights

Advanced Science, EarlyView.
Allenes emerge as powerful platforms for electrochemical functionalization through radical pathways. Selective radical addition at the central carbon triggers anodic oxidation and intramolecular cyclization, enabling efficient synthesis of oxazolines and oxazolidine‐2‐imines without external oxidants.
Pranjal Pyne, Prateek Saini, Rohel Hoque, Shivam Pandey, Srinivasan Ramakrishnan, Chandra M. R. Volla   +5 more
wiley   +1 more source

Cutaneous Tethering and Facial Dimpling As the Primary Manifestations of a Chronic Maxillary Odontogenic Cutaneous Sinus Tract: A Case Report and Focused Review of the Morphologic Evolution of Chronic Odontogenic Fistulas. [PDF]

Cureus
Shah SI, Janjua MW, Samoohi J, Swift D, Baker P.   +4 more
europepmc   +1 more source

A Robotic Testing Platform for Pipelined Discovery of Resilient Dielectric Elastomer Actuators

Advanced Science, EarlyView.
This work introduces a robotic testing platform enabling high‐throughput, multi‐parameter lifetime mapping of linear dielectric elastomer actuators (DEAs). By integrating programmable high‐voltage control and automated electromechanical measurements, the system identifies material and operating conditions that double actuator lifetime.
Ang (Leo) Li, Alexander Yin, Alexander White, Sahib Sandhu, Anatol Gogoj, Denise Maria de Andrade, Matthew Francoeur, Victor Jimenez‐Santiago, Van Remenar, Codrin Tugui, Mihai Duduta   +10 more
wiley   +1 more source

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo

Advanced Science, EarlyView.
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li, Jintian Lyu, Kaitao Li, Ameya Dravid, Deepali Balasubramani, Amir H. K. Ashkezari, Hyun‐Kyu Choi, Gabriel A. Kwong, Ankur Singh, Cheng Zhu   +9 more
wiley   +1 more source