Results 171 to 180 of about 194,394 (313)

Coagulation dysfunction events associated with novel tetracycline-class drugs: a disproportionality and Bayesian analysis based on the FAERS database. [PDF]

Front Antibiot
Li H, Wang J, Kong L, Wei Q, Shen C, Zou D.   +5 more
europepmc   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source

Development of a tetracycline-inducible programmed ribosomal frameshifting platform for sensitive regulation of mammalian gene expression. [PDF]

Nucleic Acids Res
Köse S, Müller E, Gommeringer P, Nettelbeck DM, Ungerechts G, Hartig JS.   +5 more
europepmc   +1 more source

Pyoderma Gangrenosum: A Retrospective Cohort Study of Comorbidities and Therapies in Over 65,000 Patients in the TriNetX Database

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis associated with systemic inflammatory diseases and malignancy. Although biologic therapies demonstrate efficacy in PG, the extent of their real‐world use remains incompletely characterized.
Rhiannon Grange, Tara Sholji, Marra Aghajani, Cindy Kok, John Frew   +4 more
wiley   +1 more source

Evidence that SmTetX is not a tetracycline resistance determinant. [PDF]

Microbiol Spectr
Beech MJ, Trush MM, Toma EC, Farley AJM, Walsh TR, Schofield CJ.   +5 more
europepmc   +1 more source

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

PASS-ASSISTED PREDICTION OF NOVEL TETRACYCLINE HYBRIDS [PDF]

Objective: The study aimed to determine the biological activity of various novel tetracycline hybrids using way 2 drug platform\u27s online pass software.
SUHAGIA, BHANUBHAI, SHAH, MANSI, GOSWAMI, SUNITA   +2 more
core  

Tetracycline reprograms inflammatory and regenerative signaling pathways in human keratinocytes exposed to <i>Loxosceles</i> spider venoms and sphingomyelinases. [PDF]

Front Pharmacol
Pinto BF, Lopes PH, Trufen CEM, Ching Ching AT, Junqueira de Azevedo ILM, Nishiyama-Jr MY, Tambourgi DV.   +6 more
europepmc   +1 more source

Atypical Tetracyclines Promote Longevity and Ferroptotic Neuroprotection via Translation Attenuation. [PDF]

Aging Cell
Clay KJ, Sanchez-Alavez M, Newman I, Na N, Espinoza APV, To A, Saad S, Cline HT, Petrascheck M.   +8 more
europepmc   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source