Results 61 to 70 of about 223,531 (260)

Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice

Advanced Science, EarlyView.
CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu, Xi‐xiu Xie, Lei Li, Chen Tian, Hao‐tian Wang, Xiao‐jie Wang, Xiao‐lin Yu, Gui‐feng Zhang, Rui‐tian Liu   +8 more
wiley   +1 more source

Tetracycline resistance genes of ureaplasmas [PDF]

, 2012
CITATION: Govender, S. & Chalkley, L. 2012. Tetracycline resistance genes of ureaplasmas. Southern African Journal of Epidemiology and Infection, 27(1), doi:10.1080/10158782.2012.11441475.The original publication is available at https://www.tandfonline ...
Chalkley, Lynda, Govender, Sharlene
core   +1 more source

The Potential of Self‐Maintainable Living Materials

Advanced Science, EarlyView.
Self‐maintainable living materials are presented as the next generation of bioadaptive systems, integrating continuous sensing, decision‐making, response, self‐repair, and adaptation in a closed‐loop framework. This review highlights the design principles and emerging technologies that enable autonomous, long‐term functionality for future regenerative ...
Mohammadsadegh Nadimifar, Tatiane Eufrásio‐da‐Silva, Lidia Maeso, Gorka Orive, Alireza Dolatshahi‐Pirouz   +4 more
wiley   +1 more source

Change of Electrophysical Properties of Escherichia coli Cells Due to Levomycetin and Tetracycline Action

Антибиотики и Химиотерапия, 2020
The effect of chloramphenicol and tetracycline, as inhibitors of protein synthesis, on electrophysical properties of Escherichia coli K-12 cells was investigated.
O. I. Guliy, V. D. Bunin, O. S. Larionova, E. G. Zhnichkova, A. B. Balko, O. V. Ignatov   +5 more
doaj  

One‐Step Induction of Oogonia‐Like and Pro‐Spermatogonia‐Like Cells From Porcine Pluripotent Stem Cells

Advanced Science, EarlyView.
This study established a one‐step method inducing pro‐spermatogonia‐like (activating SOX17) and oogonia‐like (activating SOX17/TFAP2C) cells from porcine pgEpiSCs with a NANOS3‐tdTomato reporter. EGF activates the core PGC program and supports survival; BMP4 further induces NANOS3 and DDX4 expression; IWR1 enhances PGCLC efficiency by suppressing ...
Pengcheng He, Liang Zhong, Tianzhi Chen, Yaxuan Yan, Xinze Chen, Runbo Li, Yingjie Wang, Yadi Teng, Minglei Zhi, Meng Wang, Jinying Zhang, Fan Zhao, Dengfeng Gao, Suying Cao, Jianyong Han   +14 more
wiley   +1 more source

Successful Tigecycline Use in Combined Therapy of Ventilator-Associated Hospital-Acquired Pneumonia: a Clinical Case

Антибиотики и Химиотерапия, 2020
In patients under artificial lung ventilation (ALV) there is often observed development of severe ventilator-associated pneumonia (VAP) due to polyresistant hospital pathogens.
G. V. Rodoman, I. R. Sumedi, S'. K. Zyryanov, M. A. Ivzhits, Q. M. Romashov, M. I. Aleksandrov, Q. Yu. Markina, M. A. Lukin, I. A. Zaigraev, M. P. Smirnova   +9 more
doaj  

Detection and characterisation of genes encoding antibiotic resistance in the cultivable oral microflora. [PDF]

, 2006
The emergence of antibiotic-resistant bacteria has become a major threat to public health. The increased use of antibiotics has selected for the dissemination of antibiotic resistance genes between organisms from different species and different genera ...
Villedieu, A., Villedieu, Aurelie
core  

Tet(M) Mediates Tetracycline Resistance in Methicillin-Resistant Staphylococcus aureus (MRSA) Clinical Isolates from the Private Hospital Sector in KwaZulu-Natal (KZN), South Africa

, 2019
To elucidate the molecular determinants of tetracycline resistance in clinical methicillin-resistant Staphylococcus aureus (MRSA) isolates from the private health sector in KwaZulu-Natal province (KZN), South Africa (SA).
John Osei Sekyere, Anou Moise Somboro, Krishnee Moodley, Linda Antoinette Bester, Daniel Gyamfi Amoako, Sabiha Yusuf Essack   +5 more
core   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Amoxicillin or tetracycline in bismuth-containing quadruple therapy for Helicobacter pylori eradication: a systematic review and meta-analysis

Frontiers in Microbiology
BackgroundAmoxicillin and tetracycline have been widely used in Helicobacter pylori (H. pylori) eradication therapy, and the priority of their efficacy and safety in Bismuth-containing Quadruple Therapy (BQT) remain controversial.Materials and methodsA ...
Kunping Ju, Qingzhou Kong, Shanling Zhang, Liangrun Zhu, Yueyue Li   +4 more
doaj   +1 more source