The catalytic activity of tyrosine 3-monooxygenase (tyrosine hydroxylase) is dependent on a tetrahydropterin cofactor and ezyme-bound iron. The oxidation of tetrahydrobiopterin by bovine adrenal tyrosine hydroxylase was studied by high performance liquid
Haavik Jan+3 more
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Über das Auftreten von Tetrahydrobiopterin und Riboflavin in den Malpighischen Gefäßen von Drosophila melanogaster und deren Mutante brown [PDF]
Dieter Eichelberg
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First insights into structure-function relationships of alkylglycerol monooxygenase [PDF]
Alkylglycerol monooxygenase is a tetrahydrobiopterin-dependent enzyme that cleaves the O-alkyl-bond of alkylglycerols. It is an exceptionally unstable, hydrophobic membrane protein which has never been purified in active form.
Fuchs, Julian E.+8 more
core
Electron paramagnetic resonance characterization of tetrahydrobiopterin radical formation in bacterial nitric oxide synthase compared to mammalian nitric oxide synthase. [PDF]
International audienceH(4)B is an essential catalytic cofactor of the mNOSs. It acts as an electron donor and activates the ferrous heme-oxygen complex intermediate during Arg oxidation (first step) and NOHA oxidation (second step) leading to nitric ...
Brunel, Albane+2 more
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Pterin Metabolism In Haemodialysis Patients
Patients undertaking maintenance haemodialysis may develop a variety of neurological disorders, the most serious of which is aluminium induced encephalopathy.
Altmann Paul+5 more
doaj +1 more source
An assay was set up for glyceryl ether monooxygenase activity in tissue samples using the novel substrate 1-O-pyrenedecyl-sn-glycerol and high-performance liquid chromatographic analysis of reaction mixtures with fluorescence detection, allowing robust ...
Ernst R. Werner+4 more
doaj
Influences of Catecholamine Contents on Tetrahydrobiopterin Metabolism
The influence of changes in catecholamine metabolism on tetrahydrobiopterin biosynthesis was investigated in cultured rat pheochromocytoma PC12 cells. The increase in the cellular dopamine content after treatment with the MAO-COMT inhibitor or dopamine ...
Kuzuya Hiroshi+2 more
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The role of tetrahydrofolate dehydrogenase in the hepatic supply of tetrahydrobiopterin in rats [PDF]
K. J. Stone
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High Protein Diet and Phenylalanine Hydroxylase Activities in Rats
The effects of a diet of 85% casein on the activities of the phenylalanine hydroxylases of rat liver and kidney have been compared. Whereas only the tetrahydrobiopterin-dependent activity of rat hepatic phenylalanine hydroxylase is significantly ...
Carty Michael P.+2 more
doaj +1 more source
Tetrahydrobiopterin metabolism in the temporal lobe of patients dying with senile dementia of Alzheimer type. [PDF]
P A Barford+5 more
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