Results 131 to 140 of about 26,569 (299)

Native and Phosphorylated Bovine Adrenal Tyrosine 3-Monooxygenase. Interactions with Tetrahydropterins and Substrate and Stability of the Formed 4a-Hydroxy-Tetrahydrobiopterin

open access: yesPteridines, 1989
The catalytic activity of tyrosine 3-monooxygenase (tyrosine hydroxylase) is dependent on a tetrahydropterin cofactor and ezyme-bound iron. The oxidation of tetrahydrobiopterin by bovine adrenal tyrosine hydroxylase was studied by high performance liquid
Haavik Jan   +3 more
doaj   +1 more source

First insights into structure-function relationships of alkylglycerol monooxygenase [PDF]

open access: yes, 2017
Alkylglycerol monooxygenase is a tetrahydrobiopterin-dependent enzyme that cleaves the O-alkyl-bond of alkylglycerols. It is an exceptionally unstable, hydrophobic membrane protein which has never been purified in active form.
Fuchs, Julian E.   +8 more
core  

Electron paramagnetic resonance characterization of tetrahydrobiopterin radical formation in bacterial nitric oxide synthase compared to mammalian nitric oxide synthase. [PDF]

open access: yes, 2012
International audienceH(4)B is an essential catalytic cofactor of the mNOSs. It acts as an electron donor and activates the ferrous heme-oxygen complex intermediate during Arg oxidation (first step) and NOHA oxidation (second step) leading to nitric ...
Brunel, Albane   +2 more
core   +3 more sources

Pterin Metabolism In Haemodialysis Patients

open access: yesPteridines, 1989
Patients undertaking maintenance haemodialysis may develop a variety of neurological disorders, the most serious of which is aluminium induced encephalopathy.
Altmann Paul   +5 more
doaj   +1 more source

Widespread occurrence of glyceryl ether monooxygenase activity in rat tissues detected by a novel assay

open access: yesJournal of Lipid Research, 2007
An assay was set up for glyceryl ether monooxygenase activity in tissue samples using the novel substrate 1-O-pyrenedecyl-sn-glycerol and high-performance liquid chromatographic analysis of reaction mixtures with fluorescence detection, allowing robust ...
Ernst R. Werner   +4 more
doaj  

Influences of Catecholamine Contents on Tetrahydrobiopterin Metabolism

open access: yesPteridines, 1998
The influence of changes in catecholamine metabolism on tetrahydrobiopterin biosynthesis was investigated in cultured rat pheochromocytoma PC12 cells. The increase in the cellular dopamine content after treatment with the MAO-COMT inhibitor or dopamine ...
Kuzuya Hiroshi   +2 more
doaj   +1 more source

High Protein Diet and Phenylalanine Hydroxylase Activities in Rats

open access: yesPteridines, 1989
The effects of a diet of 85% casein on the activities of the phenylalanine hydroxylases of rat liver and kidney have been compared. Whereas only the tetrahydrobiopterin-dependent activity of rat hepatic phenylalanine hydroxylase is significantly ...
Carty Michael P.   +2 more
doaj   +1 more source

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