Results 71 to 80 of about 13,656 (172)

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice. [PDF]

, 2015
Increased consumption of folic acid is prevalent, leading to concerns about negative consequences. The effects of folic acid on the liver, the primary organ for folate metabolism, are largely unknown.
Best, A, Caudill, MA, Christensen, KE, Deng, L, Greene, ND, Leung, KY, Lévesque, N, Malysheva, OV, Mikael, LG, Rozen, R, Wu, Q   +10 more
core   +1 more source

Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease. [PDF]

, 2019
Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous and complex disease that is imprecisely diagnosed by liver biopsy. NAFLD covers a spectrum that ranges from simple steatosis, nonalcoholic steatohepatitis (NASH) with varying degrees of fibrosis,
Alonso, Cristina, Lu, Shelly C, Mato, José M, Noureddin, Mazen   +3 more
core  

Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles [PDF]

, 2013
Background: Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) that associate with clinical phenotypes, but these SNPs usually explain just a small part of the heritability and have relatively modest
Adamski, J. (Jerzy), Aulchenko, Y.S. (Yurii), Axenovich, T.I. (Tatiana), Biloglav, Z. (Zrinka), Broer, L. (Linda), Campbell, H. (Harry), Campbell, S. (Susan), Demirkan, A. (Ayşe), Dharuri, H. (Harish), Domingues, I. (Inês), Duijn, C.M. (Cornelia) van, Floyd, J. (Jamie), Franke, L. (Lude), Franklin, C.S. (Christopher), Gieger, C. (Christian), Gnewuch, C. (Carsten), Gyllensten, U. (Ulf), Hastie, N. (Nick), Hayward, C. (Caroline), Henneman, P. (Peter), Hettne, K.M. (Kristina), Hicks, A.A. (Andrew), Hoen, P.A.C. (Peter) 't, Hofman, A. (Albert), Huffman, J.E. (Jennifer), Igl, W. (Wilmar), Isaacs, A.J. (Aaron), Jansen, R.C. (Ritsert), Janssens, A.C.J.W. (Cécile), Johansson, A. (Åsa), Jonasson, I. (Inger), Karssen, L.C. (Lennart), Kirichenko, A.V. (Anatoly), Klinken, J.B. (Jan) van, Kolcic, I. (Ivana), Liebisch, G. (Gerhard), Meitinger, T. (Thomas), Mook-Kanamori, D.O. (Dennis), Oostra, B.A. (Ben), Pattaro, C. (Cristian), Pfeufer, A. (Arne), Pichler, I. (Irene), Polasek, O. (Ozren), Pramstaller, P.P. (Peter Paul), Rivadeneira Ramirez, F. (Fernando), Roos, M. (Marco), Rudan, I. (Igor), Schmitz, G. (Gerd), Struchalin, M.V. (Maksim), Suhre, K. (Karsten), Ugocsai, P. (Peter), Uitterlinden, A.G. (André), Vitart, V. (Veronique), Wang-Sattler, R. (Rui), Wild, S.H. (Sarah), Willems van Dijk, J.A.P. (Ko), Wilson, J.F. (James F), Witteman, J.C.M. (Jacqueline), Wright, A.F. (Alan), Zaboli, G. (Ghazal), Zorkoltseva, I.V. (Irina)   +60 more
core   +1 more source

Methylamine as a nitrogen source for microorganisms from a coastal marine environment [PDF]

, 2017
Nitrogen is a key limiting resource for biomass production in the marine environment. Methylated amines, released from the degradation of osmolytes, could provide a nitrogen source for marine microbes.
Altschul, Anthony, Aziz, Bankevich, Barrett, Bicknell, Boden, Buchan, Budd, Capone, Carini, Chen, Chen, Chen, Cupples, Frebort, Friedrich, Giovannoni, Giovannoni, Giovannoni, Good, Grob, Gruber, Janvier, Janvier, Jehmlich, Kang, Koenig, Laczny, Latypova, Lee, McIntire, McTaggart, Morris, Moussard, Murrell, Naqvi, Nayak, Neff, Neufeld, Neufeld, Parks, Pinhassi, Radajewski, Rappe, Reisch, Rusch, Schaefer, Schäfer, Smith, Strand, Sun, Taubert, Todd, Tripp, Vandecandelaere, Vuilleumier, Weiner, Wischer   +58 more
core   +3 more sources

Modification and analysis of context-specific genome-scale metabolic models: methane-utilizing microbial chassis as a case study

mSystems
Context-specific genome-scale model (CS-GSM) reconstruction is becoming an efficient strategy for integrating and cross-comparing experimental multi-scale data to explore the relationship between cellular genotypes, facilitating fundamental or applied ...
M. A. Kulyashov, R. Hamilton, Y. Afshin, S. K. Kolmykov, T. S. Sokolova, T. M. Khlebodarova, M. G. Kalyuzhnaya, I. R. Akberdin   +7 more
doaj   +1 more source

Knocking down 10-formyltetrahydrofolate dehydrogenase increased oxidative stress and impeded zebrafish embryogenesis by obstructing morphogenetic movement [PDF]

[[incitationindex ...
[[corresponding]]Fu TF, Chang WN, Lee GH, Kao TT, Lin CY, Hsiao TH, Tsai JN, Chen BH, Chen YH, Wu HR, Tsai HJ, Fu TF   +1 more
core  

Transcriptional control of the H-NS antagonists LeuO and RcsB-BglJ in Escherichia coli [PDF]

, 2012
The bacterial nucleoid-associated protein (NAP) H-NS is involved in the organization and compaction of the bacterial chromatin and acts as a global respressor, mainly of genes that have been acquired by horizontal gene transfer and that are related to ...
Stratmann, Thomas
core  

The detoxification of formic acid by 10-formyl tetrahydrofolate dehydrogenase in Apis mellifera: capabilities and mechanism

, 2023
Important ecological und economic functions are performed by different pollinators. Apis mellifera being one of the most important ones, as it is managed by beekeepers worldwide. In recent years, the obligate ectoparasite Varroa destructor grew of importance as the impact on honey bee hives grew more apparent, as research has shown that it not only ...
openaire   +2 more sources

PENGARUH PEMBERIAN EKSTRAK DAUN KELOR (Moringa oleifera) TERHADAP KADAR UREUM DAN KREATININ SERUM TIKUS WISTAR YANG DIINDUKSI FORMALIN [PDF]

, 2018
Latar Belakang: Penyalahgunaan formalin sebagai pengawet makanan dapat menyebabkkan kerusakan ginjal karena stres oksidatif. Kerusakan sel akibat stres oksidatif dapat dihambat oleh antioksidan.
Kusumastuti, Aryu Candra, Puspitaningrum, Lilyn Setyorini, Tjahjono, Kusmiyati   +2 more
core  

HYDROXYMETHYL TETRAHYDROFOLIC DEHYDROGENASE

Journal of Biological Chemistry, 1957
Y, HATEFI, M J, OSBORN, L D, KAY, F M, HUENNEKENS   +3 more
openaire   +2 more sources