Results 81 to 90 of about 13,790 (193)

An Efficient CO2‐Upcycling Platform Based on Engineered Halomonas TD with Enhanced Acetate‐Utilizing Capacity via Adaptive Laboratory Evolution

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
An electrochemical system is designed to convert CO2 into CO2‐derived electrolytes (CDE), mainly containing acetate and formate. The underlying mechanism of acetate metabolism in Halomonas TD80 is explored via ALE. Engineered TD80 produced high‐yield diversified products from CDE.
Chi Wang   +18 more
wiley   +1 more source

Safety and benefits of interventions to increase folate status in malaria-endemic areas. [PDF]

open access: yes, 2017
For decades, folic acid has routinely been given to prevent or treat anaemia in children, pregnant women and people with sickle cell disease. However, there is no conclusive evidence that folate deficiency anaemia constitutes a public health problem in ...
Adjalla   +88 more
core   +1 more source

Metabolism‐Regulating Nanomedicines for Cancer Therapy

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles [PDF]

open access: yes, 2013
Background: Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) that associate with clinical phenotypes, but these SNPs usually explain just a small part of the heritability and have relatively modest
Adamski, J. (Jerzy)   +60 more
core   +1 more source

Enzymatically Synthesized Poly(Gallic Acid) Modulates Methionine Synthase Activity and Neuroblastoma Morphology in Contrast to Phthalate‐Type Endocrine Disruptors

open access: yesBiopolymers, Volume 117, Issue 1, January 2026.
ABSTRACT The effect of the enzyme‐mediated poly(gallic acid) (PGAL) as a potential redox regulator or redox activity compound (RAC) on the morphology of human neuroblastoma SH‐SY5Y cells and its methionine synthase (MS) activities is contrasted to those for disrupting compounds (EDC).
Gabriela García‐Cerón   +7 more
wiley   +1 more source

Oncometabolites: tailoring our genes [PDF]

open access: yes, 2015
Increased glucose metabolism in cancer cells is a phenomenon that has been known for over 90 years, allowing maximal cell growth through faster ATP production and redistribution of carbons towards nucleotide, protein and fatty acid synthesis.
Avril N, Buck AC, Gimm O, Higashi K
core   +1 more source

NeuralFlux: Estimation of Reaction Fluxes at a Genome‐Scale Level From Time‐Resolved Isotope Labelling Patterns Using Deep Learning

open access: yes
Plant Biotechnology Journal, Volume 24, Issue 4, Page 2076-2078, April 2026.
Sebastian Huß, Zoran Nikoloski
wiley   +1 more source

Biological Conversion of Formate to Organic Compounds: Toward a Sustainable Formate Bioeconomy

open access: yesCarbon Energy, Volume 8, Issue 1, January 2026.
Formate bioconversion plays a crucial role in achieving renewable resource utilization and sustainable development. To tap its full potential, it is important to identify the most appropriate microbial hosts for incorporating formate into building blocks, design the most promising metabolic pathways for transmitting formate into central carbon ...
Jinyi Qian   +3 more
wiley   +1 more source

Coupling metabolic footprinting and flux balance analysis to predict how single gene knockouts perturb microbial metabolism [PDF]

open access: yes, 2012
Tese de mestrado. Biologia (Bioinformática e Biologia Computacional). Universidade de Lisboa, Faculdade de Ciências, 2012The model organisms Caenorhabditis elegans and E. coli form one of the simplest gut microbe host interaction models. Interventions in
Correia, Gonçalo dos Santos, 1989-
core  

Activated brown adipose tissue releases exosomes containing mitochondrial methylene tetrahydrofolate dehydrogenase (NADP dependent) 1-like protein (MTHFD1L). [PDF]

open access: yesBiosci Rep, 2022
Leow MK   +16 more
europepmc   +1 more source

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