Results 71 to 80 of about 13,790 (193)

Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention

Cancer Medicine, Volume 15, Issue 2, February 2026.
Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa, N. D. Amal Wageesha, Sameera R. Samarakoon, Sagarika Ekanayake, H. M. Kasuni Akalanka   +4 more
wiley   +1 more source

Microbial demethylation of dimethylsulfoniopropionate and methylthiopropionate [PDF]

, 2000
As discussed in chapter 1 , there is an increased interest in the production of certain natural sulfur-containing flavor compounds or flavor precursors.
Jansen, Michael,
core   +3 more sources

Genome Analysis Reveals Diversity and Functional Potential of Novel Janthinobacterium Species From Subarctic Soils

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
The Pseudomonadota are abundant and diverse members of high‐latitude soils. Here, we describe two novel species, Janthinobacterium silvisoli and Janthinobacterium saanense, of the order Burkholderiales, isolated from tundra heath and northern boreal forest soils.
Anil Kumar, Minna K. Männistö, Lee J. Kerkhof, Max M. Häggblom   +3 more
wiley   +1 more source

Global analysis of mannitol 2-dehydrogenase in lactobacillus reuteri crl 1101 during mannitol production through enzymatic, genetic and proteomic approaches [PDF]

, 2017
Several plants, fungi, algae, and certain bacteria produce mannitol, a polyol derived from fructose. Mannitol has multiple industrial applications in the food, pharmaceutical, and medical industries, being mainly used as a non-metabolizable sweetener in ...
Bleckwedel, Juliana, Fadda, Silvina G., Hebert, Elvira Maria, Mozzi, Fernanda Beatriz, Ortiz, María Eugenia, Picariello, Gianluca, Raya, Raul Ricardo   +6 more
core   +3 more sources

Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan, Eva Troyano‐Rodriguez, Jennifer Ihuoma, Sharon Negri, Rakesh Rudraboina, Aleksandra Kosmider, Shantipriya Awasthi, Priya Balasubramanian, Shannon Conley, Andriy Yabluchanskiy, Anna Csiszar, Zoltan Ungvari, Rafael de Cabo, Stefano Tarantini   +13 more
wiley   +1 more source

Methylamine as a nitrogen source for microorganisms from a coastal marine environment [PDF]

, 2017
Nitrogen is a key limiting resource for biomass production in the marine environment. Methylated amines, released from the degradation of osmolytes, could provide a nitrogen source for marine microbes.
Altschul, Anthony, Aziz, Bankevich, Barrett, Bicknell, Boden, Buchan, Budd, Capone, Carini, Chen, Chen, Chen, Cupples, Frebort, Friedrich, Giovannoni, Giovannoni, Giovannoni, Good, Grob, Gruber, Janvier, Janvier, Jehmlich, Kang, Koenig, Laczny, Latypova, Lee, McIntire, McTaggart, Morris, Moussard, Murrell, Naqvi, Nayak, Neff, Neufeld, Neufeld, Parks, Pinhassi, Radajewski, Rappe, Reisch, Rusch, Schaefer, Schäfer, Smith, Strand, Sun, Taubert, Todd, Tripp, Vandecandelaere, Vuilleumier, Weiner, Wischer   +58 more
core   +3 more sources

The influence of rising carbon dioxide on maize development: genotypic differences in growth, lignification and folate pathway

Journal of the Science of Food and Agriculture, Volume 106, Issue 2, Page 1283-1298, 30 January 2026.
Abstract BACKGROUND Rising atmospheric carbon dioxide (CO2) is a key driver of climate change, making it essential to understand its effects on crop growth and metabolism. This study examines maize C01 (inbred) and B73 (mutant), under elevated CO2 (600, 1200 and 1800 ppm) at three growth stages [40, 70 and 90 days after sowing (DAS)].
Pirzada Khan, Sajjad Asaf, Lubna, Eman R Elsharkawy, Rahmatullah Jan, Kyung Min Kim   +5 more
wiley   +1 more source

The role of the folate pathway in pancreatic cancer risk.

PLoS ONE, 2018
BackgroundPancreatic cancer is the third leading cause of cancer related deaths in the United States. Several dietary factors have been identified that modify pancreatic cancer risk, including low folate levels.
Shirisha Chittiboyina, Zhongxue Chen, E Gabriela Chiorean, Lisa M Kamendulis, Barbara A Hocevar   +4 more
doaj   +1 more source

Comparative biochemistry of CO2 fixation and the evolution of autotrophy [PDF]

, 2010
Carbon dioxide fixation is a polyphyletic trait that has evolved in widely separated prokaryotic branches. The three principal CO2-assimilation pathways are (i) the reductive pentose-phosphate cycle, i. e.
Ana María Velasco, Antonio Lazcano, Arturo Becerra, Juli G. Peretó   +3 more
core   +2 more sources

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate [PDF]

, 2015
Serine is a both a proteinogenic amino acid and the source of one-carbon units essential for de novo purine and deoxythymidine synthesis. In the canonical glucose-derived serine synthesis pathway, Homo sapiens phosphoglycerate dehydrogenase (PHGDH ...
Abu-Remaileh, Monther, Chan, Sze Ham, Chen, Walter W., Cho, Sung Won, Chung, Haeyoon, Davidson, Shawn M, Fiske, Brian Prescott, Koh, Min Jung, Lewis, Caroline, Liu, Chieh Ming Jamin, Luengo, Alba, Pacold, Michael Edward, Sabatini, David, Sullivan, Lucas Bryan, Swier, Lotteke J. Y. M., Vander Heiden, Matthew G., Zhou, Minerva H.   +16 more
core   +1 more source