Results 41 to 50 of about 757 (166)

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer : a case-control study in a population with relatively low folate intake [PDF]

, 2008
Peer ...
Nigel T. Brockton, Cotton, SC, Linda Sharp, Masson, Lindsey F., Masson, LF, Haites, Neva E., Sharp, L, Little, Julian, Sharp, Linda, Little, J, Julian Little, Brockton, Nigel T., Lindsey F. Masson, Cotton, Seonaidh C., Seonaidh C. Cotton, Brockton, NT, Cassidy, J, Cassidy, Jim, Neva E. Haites, Haites, NE, Jim Cassidy   +20 more
core   +1 more source

Preparation and Properties of Trimethylsulfonium-Tetrahydrofolate Methyltransferase

Journal of Biological Chemistry, 1967
Abstract An enzyme that catalyzes the transfer of a methyl group from trimethylsulfonium chloride to tetrahydrofolate has been isolated from a species of Pseudomonas. This enzyme has been partially purified and several of its properties have been studied. The reaction can be formulated as a simple methyl transfer, with the formation of dimethyl sulfide
C, Wagner, S M, Lusty, H F, Kung, N L, Rogers   +3 more
openaire   +2 more sources

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

Angewandte Chemie International Edition, Volume 65, Issue 23, 1 June 2026.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source

Unveiling Candidate Markers for Drug Resistance or Synthetic Lethality in Cervical Cancer: Integrative Analysis of Genetic and Pharmacoprofiling

Cancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Introduction Systemic cervical cancer management continues to be challenging. Numerous chemotherapies have been approved, but predicting response is difficult due to the lack of biomarkers. Here, we analyze the genetic and protein profiles of 20 cervical cancer cell lines (CCCLs) and explore their correlation with drug response patterns to ...
Suzy Scholl, Elaine Del Nery, Pierre Gestraud, Maral Halladjian, Elodie Girard, Adèle Soria, Elodie Anthony, Leanne De Koning, Nicolas Servant, Els Berns, Maud Kamal   +10 more
wiley   +1 more source

Photorespiration as a Thermal Protection Mechanism in Trees: Measurements, Assumptions, and Persistent Gaps

Global Change Biology Communications, Volume 1, Issue 2, June 2026.
Conceptual framework linking leaf‐level photorespiratory biochemistry to global‐scale uncertainty in carbon cycle modelling. Rubisco acts as a temperature‐sensitive biochemical switch: At optimal temperatures (~25°C) carboxylation dominates and drives biomass accumulation, whereas heat stress (> 35°C) favours oxygenation and initiates photorespiration (
Rakesh Tiwari, Christine H. Foyer, Robert Muscarella   +2 more
wiley   +1 more source

Microbial Electrosynthesis Reshapes Energy Metabolism and Physiology in Clostridium ljungdahlii

Microbial Biotechnology, Volume 19, Issue 6, June 2026.
Microbial electrosynthesis drives Clostridium ljungdahlii into a distinct stress‐associated physiological state, different from gas fermentation. Comparative multi‐omics and electron microscopy reveal physiological constraints that help explain the poor performance of MES.
Sara Al Sbei, Santiago T. Boto, Thomas Krüger, Kai Papenfort, Martin Westermann, Aurélie Jost, Falk Harnisch, Axel A. Brakhage, Miriam A. Rosenbaum   +8 more
wiley   +1 more source

Genomic Survey of Carbon Monoxide Dehydrogenases Reveals Their Widespread Distribution in Marine Habitats

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Protein sequence surveys show that nickel‐ and molybdenum/copper‐containing carbon monoxide dehydrogenases (CODHs) are widespread in the ocean. Phylogenetic and genome context analyses reveal that marine CODHs are highly diverse in both evolutionary history and functional organisation.
Nipa Chongdar, Anand Goyal, Samir R. Damare   +2 more
wiley   +1 more source

Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion‐dependent β‐thalassaemia

British Journal of Haematology, Volume 208, Issue 6, Page 1980-1992, June 2026.
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki, Sophia Delicou, Aikaterini Ntzoura‐Kani, Nikolaos Simantiris, Marianna Politou, Veroniki Komninaka, Martina Samiotaki, Jerome Zoidakis, Marianna H. Antonelou   +8 more
wiley   +1 more source

Oxidation of Tetrahydropteridines and Tetrahydrofolates [PDF]

The autoxidation of tetrahydropteridines in aqueous media has been studied. Particular attention has been paid to tetrahydrofolic acid, which is readily oxidised in solution by air. At pH's 3, 7, 10 and 13 the products were p-aminobenzoylglutamic acid, 2-
Stocks-Wilson, R.
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