Introducing the concept of biocatalysis in the classroom: The conversion of cholesterol to provitamin D 3 [PDF]
, 2016 Biocatalysis is a fundamental concept in biotechnology. The topic integrates knowledge of several disciplines; therefore, it was included in the course “design and optimization of biological systems” which is offered in the biochemistry curricula.
De Luca, Belén M. +3 more
core +1 more source
BMC Microbiology, 2006 Background Over the last decades molecular biologic techniques have been developed to alter the genome and proteome of Tetrahymena thermophila thereby providing the basis for recombinant protein expression including functional human enzymes.
Tiedtke Arno +4 more
doaj +1 more source
La captación de colesterol por Tetrahymena thermophila se realiza principalmente por fagocitosis [PDF]
, 2018 The free-living ciliate Tetrahymena thermophila is a unicellular model organism in which landmark biological processes have been discovered, such as the first description of telomerase activity and the molecular structure of telomeres, the mechanism of ...
Cid, Nicolás Gonzalo +6 more
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The Tetrahymena thermophila Phagosome Proteome [PDF]
Eukaryotic Cell, 2006 ABSTRACT In vertebrates, phagocytosis occurs mainly in specialized cells of the immune system and serves as a primary defense against invading pathogens, but it also plays a role in clearing apoptotic cells and in tissue remodeling during development.
Mary Ellen, Jacobs +5 more
openaire +2 more sources
Crystal structure of a lipin/Pah phosphatidic acid phosphatase
Nature Communications, 2020 Lipin/Pah phosphatidic acid phosphatases generate diacylglycerol to regulate triglyceride synthesis and cellular signaling. Here authors determine structures of Tetrahymena thermophila Pah2 and identify an N-terminal amphipathic helix essential for ...
Valerie I. Khayyo +6 more
doaj +1 more source
Tetrahymena meiosis: Simple yet ingenious.
PLoS Genetics, 2021 The presence of meiosis, which is a conserved component of sexual reproduction, across organisms from all eukaryotic kingdoms, strongly argues that sex is a primordial feature of eukaryotes.
Josef Loidl
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Basal body stability and ciliogenesis requires the conserved component Poc1 [PDF]
, 2009 Centrioles are the foundation for centrosome and cilia formation. The biogenesis of centrioles is initiated by an assembly mechanism that first synthesizes the ninefold symmetrical cartwheel and subsequently leads to a stable cylindrical microtubule ...
Abal +87 more
core +2 more sources
Tetrahymena metallothioneins fall into two discrete subfamilies. [PDF]
PLoS ONE, 2007 Metallothioneins are ubiquitous small, cysteine-rich, multifunctional proteins which can bind heavy metals.We report the results of phylogenetic and gene expression analyses that include two new Tetrahymena thermophila metallothionein genes (MTT3 and ...
Silvia Díaz +8 more
doaj +1 more source
Toxic and genotoxic potential evaluation of soil samples by bioassays
Acta Agriculturae Slovenica, 2005 Soil samples were obtained from Slovenian industrial region Šaleška dolina and aqueous leachates were prepared. The toxicity and genotoxicity potential of these aqueous fractions have been evaluated by in vitro toxicity and genotoxicity bioassays ...
Barbara LAH +3 more
doaj +1 more source
Genome-wide analysis of the phosphoinositide kinome from two ciliates reveals novel evolutionary links for phosphoinositide kinases in eukaryotic cells. [PDF]
PLoS ONE, 2013 BACKGROUND: The complexity of phosphoinositide signaling in higher eukaryotes is partly due to expansion of specific families and types of phosphoinositide kinases (PIKs) that can generate all phosphoinositides via multiple routes.
George Leondaritis +3 more
doaj +1 more source