Results 41 to 50 of about 13,833 (240)

AP-1 (bZIP) Transcription Factors as Potential Regulators of Metallothionein Gene Expression in Tetrahymena thermophila

open access: yesFrontiers in Genetics, 2018
Metallothioneins (MT) are multi-stress proteins mainly involved in metal detoxification. MT gene expression is normally induced by a broad variety of stimulus and its gene expression regulation mainly occurs at a transcriptional level.
Patricia de Francisco   +3 more
doaj   +1 more source

Entry and Killing of Tetrahymena thermophila by Bacterially Produced Shiga Toxin

open access: yesmBio, 2013
Phage-encoded Shiga toxin (Stx) acts as a bacterial defense against the eukaryotic predator Tetrahymena thermophila. It is unknown how Stx enters Tetrahymena protozoa or how it kills them.
Gino Stolfa, Gerald B. Koudelka
doaj   +1 more source

Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis

open access: yeseLife, 2014
Despite the well-established role of heterochromatin in protecting chromosomal integrity during meiosis and mitosis, the contribution and extent of heterochromatic histone posttranslational modifications (PTMs) remain poorly defined.
Romeo Papazyan   +13 more
doaj   +1 more source

Effects of gelsemine on oxidative stress and DNA damage responses of Tetrahymena thermophila [PDF]

open access: yesPeerJ, 2018
Gelsemine is an important toxic substance extracted from Gelsemium elegans, which has a lot of biological functions in cells and organisms, but its toxicity has been rarely reported in Tetrahymena thermophila.
Qiao Ye   +8 more
doaj   +2 more sources

Tetrahymena Glutathione Peroxidase Family: A Comparative Analysis of These Antioxidant Enzymes and Differential Gene Expression to Metals and Oxidizing Agents

open access: yesMicroorganisms, 2020
In the present work, an extensive analysis of the putative glutathione peroxidases (GPx) of the eukaryotic microorganism model Tetrahymena thermophila is carried out.
Liliana L. Cubas-Gaona   +3 more
doaj   +1 more source

The histone chaperone Nrp1 is required for chromatin stability and nuclear division in Tetrahymena thermophila

open access: yesEpigenetics & Chromatin, 2021
Histone chaperones facilitate DNA replication and repair by promoting chromatin assembly, disassembly and histone exchange. Following histones synthesis and nucleosome assembly, the histones undergo posttranslational modification by different enzymes and
Yinjie Lian   +5 more
doaj   +1 more source

Structural basis of template-boundary definition in Tetrahymena telomerase. [PDF]

open access: yes, 2015
Telomerase is required to maintain repetitive G-rich telomeric DNA sequences at chromosome ends. To do so, the telomerase reverse transcriptase (TERT) subunit reiteratively uses a small region of the integral telomerase RNA (TER) as a template.
Akiyama, Ben M   +5 more
core   +2 more sources

The zinc finger protein Zfr1p is localized specifically to conjugation junction and required for sexual development in Tetrahymena thermophila. [PDF]

open access: yesPLoS ONE, 2012
Conjugation in Tetrahymena thermophila involves a developmental program consisting of three prezygotic nuclear divisions, pronuclear exchange and fusion, and postzygotic and exconjugant stages.
Jing Xu   +3 more
doaj   +1 more source

The bromodomain-containing protein Ibd1 links multiple chromatin related protein complexes to highly expressed genes in Tetrahymena thermophila

open access: yes, 2018
Background: The chromatin remodelers of the SWI/SNF family are critical transcriptional regulators. Recognition of lysine acetylation through a bromodomain (BRD) component is key to SWI/SNF function; in most eukaryotes, this function is attributed to ...
Burtch, Alyson   +9 more
core   +1 more source

The Co-regulation Data Harvester: Automating gene annotation starting from a transcriptome database

open access: yesSoftwareX, 2017
Identifying co-regulated genes provides a useful approach for defining pathway-specific machinery in an organism. To be efficient, this approach relies on thorough genome annotation, a process much slower than genome sequencing per se.
Lev M. Tsypin, Aaron P. Turkewitz
doaj   +1 more source

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