Results 51 to 60 of about 13,833 (240)
Angewandte Chemie, Volume 137, Issue 31, July 28, 2025.An exception or the rule? This work represents a second observation, and the first crystallographic evidence, of true intercalation of a small‐molecule ligand (here, bisquinolinium PyDH2) into an antiparallel G‐quadruplex (G4) DNA fold. Abstract G‐quadruplexes (G4s) are non‐canonical DNA structures implicated in a number of biological processes.
Kailey N. Martin +7 more
wiley +2 more sources
BMC Microbiology, 2010 Background Epitope tagging is a powerful strategy to study the function of proteins. Although tools for C-terminal protein tagging in the ciliated protozoan Tetrahymena thermophila have been developed, N-terminal protein tagging in this organism is still
Mochizuki Kazufumi +2 more
doaj +1 more source
Evolution of the mating type gene pair and multiple sexes in Tetrahymena
iScience, 2021 Summary: The multiple mating type system of the Ciliate Tetrahymena thermophila is a self/non-self recognition system, whose specificity resides in a head-to-head, functionally distinct pair of genes, MTA and MTB. We have now sequenced and analyzed these
Guanxiong Yan +7 more
doaj +1 more source
An engineered Tetrahymena tRNA(Gln) for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression [PDF]
, 1996 A new tRNA, THG73, has been designed and evaluated as a vehicle for incorporating unnatural amino acids site-specifically into proteins expressed in vivo using the stop codon suppression technique.
Abelson, John N. +7 more
core +1 more source
Genome-wide prediction of the polymorphic Ser gene family in Tetrahymena thermophila based on motif analysis. [PDF]
PLoS ONE, 2014 Even though antigenic variation is employed among parasitic protozoa for host immune evasion, Tetrahymena thermophila, a free-living ciliate, can also change its surface protein antigens.
Patrath Ponsuwanna +2 more
doaj +1 more source
Cell stress by phosphate of two protozoa tetrahymena thermophila and tetrahymena pyriformis [PDF]
, 2017 Phosphorus is one of the bioelements most needed as a compound cell by living organisms. Phosphorus is involved in several pathologies: in human with bone and kidney diseases, in mammals with metabolism disorder (glucose, insulin···), in microorganisms ...
Elkhalfi, Bouchra +4 more
core +1 more source
Gene network landscape of the ciliate Tetrahymena thermophila. [PDF]
PLoS ONE, 2011 Genome-wide expression data of gene microarrays can be used to infer gene networks. At a cellular level, a gene network provides a picture of the modules in which genes are densely connected, and of the hub genes, which are highly connected with other ...
Jie Xiong +9 more
doaj +1 more source
Macronuclear DNA molecules of Tetrahymena thermophila. [PDF]
Molecular and Cellular Biology, 1986 The physical organization of the DNA in the macronuclei of Tetrahymena thermophila was investigated by using alternating-orthogonal-field gel electrophoresis. The genome consisted of a spectrum of molecules with lengths ranging from less than 100 to in excess of 1,500 kilobase pairs.
R K, Conover, C F, Brunk
openaire +2 more sources
Cytoskeleton, EarlyView.ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius +6 more
wiley +1 more source
RACS: Rapid Analysis of ChIP-Seq data for contig based genomes
, 2019 Background: Chromatin immunoprecipitation coupled to next generation sequencing (ChIP-Seq) is a widely used technique to investigate the function of chromatin-related proteins in a genome-wide manner. ChIP-Seq generates large quantities of data which can
Fillingham, Jeffrey +3 more
core +1 more source