Results 91 to 100 of about 435 (116)

ChemInform Abstract: Dispiro‐1,2,4,5‐tetraoxanes: A New Class of Antimalarial Peroxides.

ChemInform, 1992
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
James K. Wood, Jonathan L. Vennerstrom, William Y. Ellis, Wilbur K. Milhous, Hong Ning Fu, Lucia Gerena, Steven L. Andersen, Arba L. Ager   +7 more
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ChemInform Abstract: Phosphomolybdic Acid Catalyzed Synthesis of 1,2,4,5‐Tetraoxanes. [PDF]

ChemInform, 2011
AbstractThe condensation of dihydroperoxides and carbonyl compounds is achieved using phosphonomolybdic acid as the catalyst and anhydrous magnesium sulfate as water scavenger to yield spirocyclic tetraoxanes as subunits of antimalarial drugs.
Yun-Ting Zhu, Jinglei Chen, Chunhua Qiao, Xing Yan   +3 more
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Thermal decomposition of cyclic alkylidine peroxides (tetraoxanes)

Thermochimica Acta, 1974
Abstract Thermal decomposition of molten 6,6-bis-(4-methoxycarbonyl-butyl)-1,2,4,5-tetraoxane has kinetic parameters similar to those of the other dialkyl peroxides: A similar behaviour has also been found for 6,6-bis-(4-aminocarbonyl-butyl)-1,2,4,5-tetraoxane dissolved in dimethylformamide: In the absence of solvent this cyclic dimeric ...
Milan Lazár, Eberhard Borsig, P. Ambrovič   +2 more
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Radiation‐induced polymerization of tetraoxane in the solid state

Journal of Polymer Science Part A-1: Polymer Chemistry, 1971
AbstractThe radiation‐induced polymerization of tetraoxane in the solid state has been investigated in air and in vacuo. The polymerization rate was higher in air than in vacuo, whereas the molecular weight of the polymer obtained at high conversion in air was considerably lower than in vacuo.
Masaru Yoshida, Yoshiaki Nakase, Akihiko Ito, Koichiro Hayashi   +3 more
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Antimalarial and Anticancer Activity Evaluation of Bridged Ozonides, Aminoperoxides, and Tetraoxanes

ChemMedChem, 2022
AbstractBridged aminoperoxides, for the first time, were investigated for the in vitro antimalarial activity against the chloroquine‐resistant Plasmodium falciparum strain K1 and for their cytotoxic activities against immortalized human normal liver (LO2) and lung (BEAS‐2B) cell lines as well as human liver (HepG2) and lung (A549) cancer cell lines ...
Paolo Coghi, Ivan A. Yaremenko, Parichat Prommana, Jia Ning Wu, Rui Long Zhang, Jerome P. L. Ng, Yulia Yu. Belyakova, Betty Yuen Kwan Law, Peter S. Radulov, Chairat Uthaipibull, Vincent Kam Wai Wong, Alexander O. Terent'ev   +11 more
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Synthesis and Antimalarial Activity of 1,2,4,5‐Tetraoxanes

ChemInform, 2002
Methods for formation of 1,2,4,5-tetraoxanes are summarized and antimalarial activities of 1,2,4,5-tetraoxanes are discussed.
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Mixed Steroidal 1,2,4,5-Tetraoxanes:  Antimalarial and Antimycobacterial Activity

Journal of Medicinal Chemistry, 2002
Mixed 1,2,4,5-tetraoxanes possessing simple spirocycloalkane and spirocholic acid-derived substituents were prepared and shown to have significantly higher in vitro antimalarial activity than bis-substituted tetraoxanes. Out of 41 synthesized tetraoxanes, 12 were in vitro more potent against Plasmodium falciparum chloroquine-resistant W2 clone than ...
Solaja BA, Terzic N, Pocsfalvi G, Gerena L, Tinant B, Opsenica D, Milhous WK   +6 more
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ChemInform Abstract: Metalloporphyrin‐Catalyzed Decomposition of Cyclic Diperoxides (1,2,4,5‐Tetraoxanes).

ChemInform, 1986
La decomposition des tetroxannes substituees est fortement catalysee par addition de ZnTPP ou CoTPP et conduit a la formation d'une cetone C 6 H 5 COR et d'un ester (ou d'un acide) C 6 H 5 CO 2 R comme produits principaux.
Mutsuo Tone, Teruo Matsuura, Hiroaki Yokoya, Yoshikatsu Ito, Gary B. Schuster   +4 more
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Tetraoxanes as a new class of efficient herbicides comparable with commercial products

Pest Management Science, 2014
AbstractBACKGROUNDSeveral 1,2,4,5‐tetraoxanes were synthesised, and their herbicidal activity was tested against weeds and compared with the activity of commercial herbicides glyphosate and imazethapyr.RESULTSThe compounds were prepared by reacting carbonyl compounds with hydrogen peroxide under acid catalysis, affording 1,1‐dihydroperoxides (36–91 ...
Célia R. A. Maltha, Raphael Campos Cusati, Luiz C. A. Barbosa, Luiz C. A. Barbosa, Alberto Oliveros-Bastidas, Antonio Alberto da Silva, Antonio J. Demuner   +6 more
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New Chimeric Antimalarials with 4-Aminoquinoline Moiety Linked to a Tetraoxane Skeleton [PDF]

Journal of Medicinal Chemistry, 2008
The synthesis of the chimeric molecules consisting of two pharmacophores, tetraoxane and 7-chloro-4-aminoquinoline, is reported. The tetraoxanes 2, 4, and 8 show relatively potent in vitro antimalarial activities, with IC90 values for the Plasmodium falciparum strain W2 of 2.26, 12.44, and 10.74 nM, respectively.
Opsenica, Igor, Opsenica, Dejan, Lanteri, C.A., Anova, L., Milhous, Wilbur K., Smith, K. S., Šolaja, Bogdan   +6 more
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