Results 121 to 130 of about 398 (143)

Synthesis and Antimalarial Activity of 1,2,4,5‐Tetraoxanes

ChemInform, 2002
Methods for formation of 1,2,4,5-tetraoxanes are summarized and antimalarial activities of 1,2,4,5-tetraoxanes are discussed.
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Thermal decomposition of cyclic alkylidine peroxides (tetraoxanes)

Thermochimica Acta, 1974
Abstract Thermal decomposition of molten 6,6-bis-(4-methoxycarbonyl-butyl)-1,2,4,5-tetraoxane has kinetic parameters similar to those of the other dialkyl peroxides: A similar behaviour has also been found for 6,6-bis-(4-aminocarbonyl-butyl)-1,2,4,5-tetraoxane dissolved in dimethylformamide: In the absence of solvent this cyclic dimeric ...
M. Lazár, P. Ambrovič, E. Borsig
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Antimalarial and Anticancer Activity Evaluation of Bridged Ozonides, Aminoperoxides, and Tetraoxanes

ChemMedChem, 2022
AbstractBridged aminoperoxides, for the first time, were investigated for the in vitro antimalarial activity against the chloroquine‐resistant Plasmodium falciparum strain K1 and for their cytotoxic activities against immortalized human normal liver (LO2) and lung (BEAS‐2B) cell lines as well as human liver (HepG2) and lung (A549) cancer cell lines ...
Paolo Coghi, Ivan A. Yaremenko, Parichat Prommana, Jia Ning Wu, Rui Long Zhang, Jerome P. L. Ng, Yulia Yu. Belyakova, Betty Yuen Kwan Law, Peter S. Radulov, Chairat Uthaipibull, Vincent Kam Wai Wong, Alexander O. Terent'ev   +11 more
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Metalloporphyrin-catalyzed decomposition of cyclic diperoxides (1,2,4,5-tetraoxanes)

The Journal of Organic Chemistry, 1986
La decomposition des tetroxannes substituees est fortement catalysee par addition de ZnTPP ou CoTPP et conduit a la formation d'une cetone C 6 H 5 COR et d'un ester (ou d'un acide) C 6 H 5 CO 2 R comme produits principaux.
Yoshikatsu Ito, Mutsuo Tone, Hiroaki Yokoya, Teruo Matsuura, Gary B. Schuster   +4 more
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Mixed steroidal tetraoxanes induce apoptotic cell death in tumor cells

Investigational New Drugs, 2008
In this study we investigated the antiproliferative activity of six mixed steroidal tetraoxanes against various tumor cell lines, the toxicity against normal peripheral blood mononuclear cells (PBMC), and the mode of HeLa cell death induced by these compounds.
Žižak, Željko, Juranić, Zorica, Opsenica, Dejan, Šolaja, Bogdan   +3 more
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Radiation‐induced solid state polymerization of tetraoxane

Journal of Polymer Science Part B: Polymer Letters, 1963
The radioinduced polymerization of tetraoxane is reported and compared with that of trioxane. Under gamma irradiation at 80 deg C and at a dose rate of 2.5 x 10/sup 4/ r/hr, tetraoxane became gradually opaque. After 18 hr irradiation a polymer crystal with the shape of the monomer crystal was obtained at 94% conversion. However, no polymer was obtained
K. Hayashi, H. Ochi, M. Nishii, Y. Miyake, S. Okamura   +4 more
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Synthesis and antimalarial activities of novel 3,3,6,6-tetraalkyl-1,2,4,5-tetraoxanes

Bioorganic & Medicinal Chemistry, 2006
The oxidative system H2O2/fluorinated alcohol (TFE, HFIP) was used for direct acid- and MeReO3-catalyzed synthesis of 1,2,4,5-tetraoxanes from cyclic (C6, C7, and C12) and acyclic ketones. The influence of ring size and alkyl chain length were studied and antimalarial activities of synthetic 3,3,6,6-tetraalkyl-1,2,4,5-tetraoxanes were determined ...
Zmitek, K, Stavber, S, Zupan, M, Bonnet-Delpon, D., Charneau, Sébastien, Grellier, Philippe, Iskra, J   +6 more
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Radiation‐induced polymerization of tetraoxane in the solid state

Journal of Polymer Science Part A-1: Polymer Chemistry, 1971
AbstractThe radiation‐induced polymerization of tetraoxane in the solid state has been investigated in air and in vacuo. The polymerization rate was higher in air than in vacuo, whereas the molecular weight of the polymer obtained at high conversion in air was considerably lower than in vacuo.
Yoshiaki Nakase, Masaru Yoshida, Akihiko Ito, Koichiro Hayashi   +3 more
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ChemInform Abstract: Phosphomolybdic Acid Catalyzed Synthesis of 1,2,4,5‐Tetraoxanes.

ChemInform, 2012
AbstractThe condensation of dihydroperoxides and carbonyl compounds is achieved using phosphonomolybdic acid as the catalyst and anhydrous magnesium sulfate as water scavenger to yield spirocyclic tetraoxanes as subunits of antimalarial drugs.
Xing Yan, Jinglei Chen, Yun‐Ting Zhu, Chunhua Qiao   +3 more
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Chemiluminescence in decomposition of bridged 1,2,4,5-tetraoxanes catalyzed by ferrocene

Mendeleev Communications, 2017
Chemiluminescence was observed in ferrocene-catalyzed decomposition of bridged 1,2,4,5-tetraoxanes, namely, 2,3,5,6-tetraoxabicyclo[2.2.1]heptanes. The chemi- and photoluminescence spectra revealed the main products and luminescence emitters to be β-diketones.
Dim I. Galimov, Dilara R. Gazeeva, Ramil G. Bulgakov, Alexander O. Terent’ev   +3 more
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