Results 41 to 50 of about 386 (143)

A Brief Review on Manipulation of Essential Metal Ions as Nanomedicine for Cancer Therapy

Advanced NanoBiomed Research, Volume 4, Issue 2, February 2024.
In this review, the latest progression of essential metal‐ion‐based nanomedicine for tumor therapy is summarized, existing challenges are addressed, and possible directions of such therapeutic strategies are proposed. Such information benefits readers a general awareness for current research status and implication of the future clinical applications ...
Lin Weng, Xin Chen
wiley   +1 more source

Synthesis of some novel steroidal 1,2,4,5-tetraoxanes

RSC Advances, 2015
A facile synthesis of A-ring manipulated C-20 methyl carboxylate steroid derivative with unsymmetrical dispiro 1,2,4,5-tetraoxanes has been focused herein via acid catalyzed cyclocondensation of bis-epidioxy ketone.
Manash Protim Hazarika, Archana Moni Das
openaire   +2 more sources

Synthesis and initial testing of novel antimalarial and antitubercular isonicotinohydrazides

Results in Chemistry, 2022
Malaria and tuberculosis (TB) though curable and preventable, remain serious public health problems globally, with devastating consequences. Co-infection of these two deadly diseases worsens the situation and particularly makes treatment very difficult ...
Richard K. Amewu, Crystal F. Ade, Isaac Darko Otchere, Portia Morgan, Dorothy Yeboah-Manu   +4 more
doaj  

Optimisation of the synthesis of second generation 1,2,4,5 tetraoxane antimalarials

Tetrahedron, 2016
Abstract An efficient route to the synthesis of potent antimalarial aryloxy 1,2,4,5-tetraoxanes is described that permits parallel synthesis for Structure–Activity Relationship (SAR) investigations. Brief details of the in vitro and in vivo antimalarial evaluation are included which enables identification of antimalarial leads for further development.
Natalie L. Roberts, Emma R. Shore, Matthew J. Schnaderbeck, Richard Amewu, Stephen A. Ward, Sunil Sabbani, Paul McGillan, Gemma L. Nixon, Jill Davies, Ben Murphy, Christopher Riley, Paul O´Neill   +11 more
openaire   +2 more sources

Cover Feature: Catalyst Development for the Synthesis of Ozonides and Tetraoxanes Under Heterogeneous Conditions: Disclosure of an Unprecedented Class of Fungicides for Agricultural Application (Chem. Eur. J. 21/2020) [PDF]

, 2020
Ivan A. Yaremenko, Peter S. Radulov, Yulia Yu. Belyakova, Arina A. Demina, Dmitri I. Fomenkov, Denis V. Barsukov, И. Р. Субботина, Fabrice Fleury, Alexander O. Terent’ev   +8 more
openalex   +1 more source

Graph isomorphism-based algorithm for cross-checking chemical and crystallographic descriptions. [PDF]

J Cheminform, 2023
Merkys A, Vaitkus A, Grybauskas A, Konovalovas A, Quirós M, Gražulis S.   +5 more
europepmc   +1 more source

Lewis Acids and Heteropoly Acids in the Synthesis of Organic Peroxides. [PDF]

Pharmaceuticals (Basel), 2022
Yaremenko IA, Radulov PS, Belyakova YY, Fomenkov DI, Tsogoeva SB, Terent'ev AO.   +5 more
europepmc   +1 more source

Identification of Potential Antiviral Inhibitors from Hydroxychloroquine and 1,2,4,5-Tetraoxanes Analogues and Investigation of the Mechanism of Action in SARS-CoV-2 [PDF]

, 2022
Ryan da Silva Ramos, Rosivaldo S. Borges, João Sammy Nery de Souza, Inana F. Araújo, Mariana Helena Chaves, Cleydson B. R. Santos   +5 more
openalex   +1 more source

Differentiation between 1,2,4,5‐tetraoxanes and 1,2,4,5,7,8‐hexaoxonanes using ¹H and ¹³C NMR analyses [PDF]

, 2001
Yuxiang Dong, Jonathan L. Vennerstrom
openalex   +1 more source

Artefenomel Regioisomer RLA-3107 Is a Promising Lead for the Discovery of Next-Generation Endoperoxide Antimalarials. [PDF]

ACS Med Chem Lett, 2023
Blank BR, Gut J, Rosenthal PJ, Renslo AR.   +3 more
europepmc   +1 more source