Results 191 to 200 of about 132,391 (265)

<i>Humulus lupulus</i> (Hop)-Derived Chemical Compounds Present Antiproliferative Activity on Various Cancer Cell Types: A Meta-Regression Based Panoramic Meta-Analysis. [PDF]

Pharmaceuticals (Basel)
Tsionkis G, Andronidou EM, Kontou PI, Tamposis IA, Tegopoulos K, Pergantas P, Grigoriou ME, Skavdis G, Bagos PG, Braliou GG.   +9 more
europepmc   +1 more source

Therapeutic potential of spexin in diabetic neuropathy: Insights from in vitro and in vivo models

Experimental Physiology, EarlyView.
Abstract The present study investigated the therapeutic potential of spexin (SPX) on both in vitro and in vivo models of diabetic neuropathy (DN). A total of 40 male BALB/c mice were randomly allocated into four experimental groups (n = 10 per group): a normoglycaemic control, an untreated DN group and two SPX treatment groups (DN+SPX‐12.5 and DN+SPX ...
Mehmet Refik Bahar, Seval Ulku Orhan, Cigdem Tekin, Asli Taslidere, Mete Ozcan, Suat Tekin   +5 more
wiley   +1 more source

Biological Effects of Bioactive Glass-Containing Self-Adhesive Resin Cements on Dental Pulp Stem Cells. [PDF]

J Funct Biomater
Kwon J, Chae SW, Kim HJ.
europepmc   +1 more source

Performance Thresholds of Fishmeal Replacement in Probiotic‐Supplemented Alternative Protein Diets for Climbing Perch (Anabas testudineus)

Aquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.
ABSTRACT Reducing fishmeal (FM) use in aquafeeds is essential for sustainable aquaculture, but excessive replacement with alternative proteins may impair fish growth and physiological performance. This study evaluated the performance thresholds of graded FM replacement in probiotic‐supplemented alternative protein diets for climbing perch (Anabas ...
Farjana Khanam Chadnee, Iftekhar Ahmed Fagun, Md. Shakil Khan, Md. Abu Talha, Chayanika Pondit, Md. Sakhawat Hossain   +5 more
wiley   +1 more source

Telmisartan increases olaparib efficacy in homologous recombination proficient tumors by augmenting type I interferon production. [PDF]

J Immunother Cancer
Murray CE, Ontiveros CO, Wentworth J, Blinkiewicz P, Leung B, Bai H, Spicer N, Holtz A, Tanner C, Balasubramanian A, Li W, Dray E, Zhao W, Curiel TJ.   +13 more
europepmc   +1 more source

Expanding the Phenotype of TUFM ‐Related Combined Oxidative Phosphorylation Deficiency 4

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1884-1889, August 2026.
ABSTRACT Combined oxidative phosphorylation deficiency 4 (COXPD4) is a rare mitochondrial condition caused by biallelic deleterious variants in the nuclear‐encoded gene TUFM. To date, most individuals with COXPD4 have presented with encephalopathy, hypotonia, and abnormal brain imaging. Many of the reported individuals died in infancy. We aim to expand
Noémie Villeneuve‐Cloutier, Jodi Warman‐Chardon, Danielle K. Bourque   +2 more
wiley   +1 more source

Assessment of the cytotoxicity of commercially available titanium alloy with pure grade titanium (CP-Ti) and other alloying elements for dental implants: An <i>in vitro</i> study. [PDF]

Natl J Maxillofac Surg
Nair VS, Sankar K, Kshirsagar R, Sane VD, Nallasivamoorthy A, Singh V.   +5 more
europepmc   +1 more source

Design, Synthesis, and Biological Evaluation of Chiral Urea and Thiourea Derivatives as Multitarget‐Directed Anti‐Alzheimer Agents

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A series of novel chiral urea and thiourea compounds were designed as multitarget‐directed ligands for Alzheimer's disease and evaluated against hAChE, hBChE, and hMAO‐B, with exploratory assessment of HSD10. These chiral compounds were synthesized and fully characterized, and their enantiopurity was confirmed via HPLC.
Sule Erol Gunal, Senel Teke Tuncel, İlke Demir, İpek Baysal, Gökçen Telli, Safiye Sag Erdem, Gulberk Ucar, Michaela Hanzlova, Kamil Musilek, İlknur Dogan, Nesrin Gokhan Kelekci   +10 more
wiley   +1 more source

Two Novel 1,4‐Naphthoquinone Derivatives as Potent Agents Against Multidrug‐Resistant Staphylococcus aureus and Pathogenic Gram‐Positive Bacteria

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Drug‐resistant bacteria such as Methicillin‐resistant Staphylococcus aureus (MRSA) and Quinolone‐resistant S. aureus (QRSA), are a growing problem, creating a need for the development of novel antimicrobial agents. In this study, we designed and synthesized two novel 1,4‐naphthoquinone derivatives, LHN‐1034 and LHN‐1035, and evaluated their ...
HyunChan Song, Haena Lee, Ji‐Hyun Yoon, Hyunkyung Choi, Hakwon Kim, Ki‐Young Kim   +5 more
wiley   +1 more source