Results 31 to 40 of about 209,741 (306)
UPLC-MS/MS analysis of ochratoxin A metabolites produced by Caco-2 and HepG2 cells in a co-culture system [PDF]
Ochatoxin A (OTA) is one of the most important mycotoxins based on its toxicity. The oral route is the main gateway of entry of OTA into the human body, and specialized epithelial cells constitute the first barrier.
González Arias, Cyndia A. +4 more
core +2 more sources
Sowing seasons and qualitative performance of soybean seeds
Changes in the soybean sowing season directly reflect on the physiological potential of the seeds produced. This study aimed to identify sowing seasons that qualitatively improve the soybean seeds yield.
Elesandro Bornhofen +3 more
doaj +1 more source
Inhalable spray-dried chondroitin sulphate microparticles: effect of different solvents on particle properties and drug activity [PDF]
Spray-drying stands as one of the most used techniques to produce inhalable microparticles, but several parameters from both the process and the used materials affect the properties of the resulting microparticles.
Buttini, Francesca +6 more
core +1 more source
Suitability of tetrazolium test for Tamarindus indica L. seeds
Seed quality is routinely assessed by direct tests, e.g, the germination test, or indirect tests like the tetrazolium test, which has shoown to be promising in the determine viability and vigor, allowing the diagnosis of the main problems that may affect
Luciana Nunes Cordeiro +5 more
doaj +1 more source
Clionasterol, a triterpenoid from the Kenyan marine green macroalga halimeda macroloba [PDF]
Peer reviewedPublisher ...
Dzeha, Thomas +2 more
core +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles [PDF]
The study reports the initial biological evaluation of targeted polymeric glycol chitosan vesicles as carrier systems for doxorubicin (Dox). Transferrin (Tf) was covalently bound to the Dox-loaded palmitoylated glycol chitosan (GCP) vesicles using ...
Couet, William +5 more
core +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A avaliação da qualidade fisiológica de sementes é um aspecto importante para o controle das plantas daninhas. Objetivou-se verificar a viabilidade de sementes de Euphorbia heterophylla resistentes e suscetíveis a herbicidas, após serem armazenadas ...
J.R. Aarestrup +3 more
doaj +1 more source

