Results 31 to 40 of about 209,741 (306)

UPLC-MS/MS analysis of ochratoxin A metabolites produced by Caco-2 and HepG2 cells in a co-culture system [PDF]

open access: yes, 2017
Ochatoxin A (OTA) is one of the most important mycotoxins based on its toxicity. The oral route is the main gateway of entry of OTA into the human body, and specialized epithelial cells constitute the first barrier.
González Arias, Cyndia A.   +4 more
core   +2 more sources

Sowing seasons and qualitative performance of soybean seeds

open access: yesPesquisa Agropecuária Tropical, 2015
Changes in the soybean sowing season directly reflect on the physiological potential of the seeds produced. This study aimed to identify sowing seasons that qualitatively improve the soybean seeds yield.
Elesandro Bornhofen   +3 more
doaj   +1 more source

Inhalable spray-dried chondroitin sulphate microparticles: effect of different solvents on particle properties and drug activity [PDF]

open access: yes, 2020
Spray-drying stands as one of the most used techniques to produce inhalable microparticles, but several parameters from both the process and the used materials affect the properties of the resulting microparticles.
Buttini, Francesca   +6 more
core   +1 more source

Suitability of tetrazolium test for Tamarindus indica L. seeds

open access: yesSemina: Ciências Agrárias, 2022
Seed quality is routinely assessed by direct tests, e.g, the germination test, or indirect tests like the tetrazolium test, which has shoown to be promising in the determine viability and vigor, allowing the diagnosis of the main problems that may affect
Luciana Nunes Cordeiro   +5 more
doaj   +1 more source

Clionasterol, a triterpenoid from the Kenyan marine green macroalga halimeda macroloba [PDF]

open access: yes, 2003
Peer reviewedPublisher ...
Dzeha, Thomas   +2 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles [PDF]

open access: yes, 2004
The study reports the initial biological evaluation of targeted polymeric glycol chitosan vesicles as carrier systems for doxorubicin (Dox). Transferrin (Tf) was covalently bound to the Dox-loaded palmitoylated glycol chitosan (GCP) vesicles using ...
Couet, William   +5 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Análise da viabilidade de sementes de Euphorbia heterophylla Viability analysis of Euphorbia heterophylla seeds

open access: yesPlanta Daninha, 2008
A avaliação da qualidade fisiológica de sementes é um aspecto importante para o controle das plantas daninhas. Objetivou-se verificar a viabilidade de sementes de Euphorbia heterophylla resistentes e suscetíveis a herbicidas, após serem armazenadas ...
J.R. Aarestrup   +3 more
doaj   +1 more source

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