Results 141 to 150 of about 24,486 (253)

Citrate‐Dependent Activation of Acetyl CoA Carboxylase Promotes Renal Lipid Accumulation in a Rat Model of Chronic Kidney Disease

open access: yesActa Physiologica, Volume 242, Issue 5, May 2026.
ABSTRACT Background Abnormal accumulation of lipids within the kidney contributes to the progression of chronic kidney disease, but the underlying metabolic mechanisms remain unclear. Citrate is a central metabolite in cellular energy regulation and is frequently elevated in advanced kidney disease, yet its impact on renal lipid metabolism has not been
Marta Sanz‐Gómez   +8 more
wiley   +1 more source

Rapid screening of inhibitors of Mycobacterium tuberculosis growth using tetrazolium salts. [PDF]

open access: yesMethods Mol Biol, 2009
Amin AG   +3 more
europepmc   +1 more source

Novel Molecules for Intra-Oral Delivery of Antimicrobials to Prevent and Treat Oral Infectious Diseases [PDF]

open access: yes, 2008
New molecules were designed for efficient intra-oral delivery of antimicrobials to prevent and treat oral infection. The salivary statherin fragment, which has high affinity for the tooth enamel, was used as a carrier peptide. This was linked through the
Dentino, Andrew R.   +2 more
core   +1 more source

The MdICE1/MdFAMA‐MdTYDC Transcriptional Module Confers Cold Tolerance by Regulating Dopamine Metabolism in Apple

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 3012-3031, May 2026.
ABSTRACT Low temperature is a critical abiotic stress that imposes major constraints on the sustainable development of the fruit tree industry. Although exogenous dopamine has been shown to enhance cold tolerance in plants, its molecular mechanisms in apple (Malus domestica) remain poorly understood.
Kexin Tan   +9 more
wiley   +1 more source

Lily Transcription Factors LlPLATZ1 and LlMYB4 Orchestrate the Homeostasis of Heat Stress Responses via Antagonistic Regulation of LlHSF24

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 3407-3425, May 2026.
ABSTRACT Heat stress significantly damages crop yield and quality. PLATZ (PLANT A/T‐RICH SEQUENCE‐AND ZINC‐BINDING PROTEIN) transcription factors play pivotal roles in plant growth, development, and environmental stress responses. While the functions of PLATZ members in response to drought and salt stress are well characterised, their roles in heat ...
Xue Gong   +7 more
wiley   +1 more source

Viable but Nonculturable State, a Survival Strategy for Salmonella in Aquatic Environments

open access: yesWater and Environment Journal, Volume 40, Issue 2, Page 183-202, May 2026.
Transition of Salmonella from a culturable state to a viable but nonculturable state under various environmental stresses and current methods for detecting viable Salmonella in environmental samples. ABSTRACT In the relentless battle for survival, Salmonella has evolved mechanisms to withstand harsh conditions such as extreme temperatures, fluctuating ...
Sanelisiwe Thinasonke Duze   +3 more
wiley   +1 more source

Chemo‐Enzymatic Route for Covalent Cellulose Fiber Dyeing

open access: yesChemistry – A European Journal, Volume 32, Issue 14, 15 April 2026.
This work presents a proof of concept for a chemo‐enzymatic approach to the covalent dyeing of cotton fibers. Laccase/TEMPO oxidation introduces aldehyde groups, enabling subsequent reductive amination with amino dyes. Excellent color homogeneity and wash fastness were demonstrated using acid red 33, highlighting the robustness of the approach and its ...
Awilda Maccow   +6 more
wiley   +1 more source

Britannilactone 1-O-acetate induced ubiquitination of NLRP3 inflammasome through TRIM31 as a protective mechanism against reflux esophagitis-induced esophageal injury

open access: yesChinese Medicine
Background Reflux esophagitis (RE) is a disease in which inflammation of the esophageal mucosa owing to the reflux of gastric contents into the esophagus results in cytokine damage.
Ju Liu   +7 more
doaj   +1 more source

2‐Phenylquinolines Exhibit Anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 Activity Through the Nonstructural Protein 13 Helicase Inhibition

open access: yesChemMedChem, Volume 21, Issue 7, 14 April 2026.
A SAR study led to the identification of new 2‐phenylquinoline‐based derivatives that exhibit anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) activity by acting as ATP‐competitive inhibitors of nonstructural protein 13 (nsp13) helicase.
Giada Cernicchi   +24 more
wiley   +1 more source

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