Results 41 to 50 of about 24,486 (253)

Synthesis of 3-(phenylazo)-1,2,4-triazoles by a nucleophilic reaction of primary amines with 5-chloro-2,3-diphenyltetrazolium salt via mesoionic 2,3-diphenyltetrazolium-5-aminides

open access: yesBeilstein Journal of Organic Chemistry, 2009
The reactions of a 5-chloro-2,3-diphenyltetrazolium salt with amines have been examined. In the presence of an inorganic base such as NaHCO3, primary and secondary amines undergo a nucleophilic substitution to give the corresponding 5-aminotetrazolium ...
Shuki Araki   +4 more
doaj   +1 more source

Synthesis of Novel Quaternary Ammonium Salts and Their in Vitro Antileishmanial Activity and U-937 Cell Cytotoxicity

open access: yesMolecules, 2016
This work describes the synthesis of a series of quaternary ammonium salts and the assessment of their in vitro antileishmanial activity and cytotoxicity.
Sandra M. Duque-Benítez   +6 more
doaj   +1 more source

Neotetrazolium salt (NT) as an electron acceptor in living cell: a study on the JTC-3 and HeLa cells in culture [PDF]

open access: yes, 1965
1. By using a monolayer of tissue culture cells, JTC-3, JTC-3', JTC-3" and HeLa cells, the assays of neotetrazolium (NT) reduction at the cell level have been conducted on the cells without detaching the cells from the culture glass vessel wall.
Manabe, Toyohiko
core   +1 more source

Anti-Toxoplasma Effect of Hydroalchohlic Extract of Terminalia chebula Retz in Cell Culture and Murine Model

open access: yesIranian Journal of Parasitology, 2021
Background: We examined anti-Toxoplasma effect of hydroalcoholic extract of Terminalia chebula Retz (T. chebula) in cell culture and murine model. Methods: The study was conducted in Shahrekord University of Medical Sciences, Iran in 2017.
Mahnaz Jafari   +3 more
doaj  

Vital dye reaction and granule localization in periplasm of Escherichia coli.

open access: yesPLoS ONE, 2012
BackgroundTetrazolium salts are widely used in biology as indicators of metabolic activity - hence termed vital dyes - but their reduction site is still debated despite decades of intensive research.
Liyan Ping   +4 more
doaj   +1 more source

The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls [PDF]

open access: yes, 2010
Nonviral gene complexes can enter mammalian cells through different endocytic pathways. For efficient optimization of the gene carrier it is important to profile its cellular uptake, because this largely determines its intracellular processing and ...
Dries Vercauteren   +57 more
core   +3 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Half-Sandwich Ir(III) and Os(II) Complexes of Pyridyl-Mesoionic Carbenes as Potential Anticancer Agents [PDF]

open access: yes, 2019
A series of cationic chlorido arene-iridium(III) and arene-osmium(II) complexes with bidentate pyridyl functionalized mesoionic carbenes (MIC) of the 1,2,3-triazol-5-ylidene type have been prepared.
Bolje, Aljoša   +12 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Application of extreme environmental conditions to resuscitation of viable but non culturable E. coli DH5α [PDF]

open access: yes, 2012
The resuscitation of Viable But Non-Culturable (VBNC) state in Escherichia coli DH5α as one of the most usable expression host was investigated.
Eftekharei, M.   +6 more
core  

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