The toxic mechanism and application of tetrodotoxin (TTX) [PDF]
MATEC Web of ConferencesTetrodotoxin (TTX) is a powerful toxin related to nerve cells that is commonly discovered at loads of puffer fish, and working out the best way of cooking, whereas keeping the flavour but getting rid of the toxicity has challenged people for decades, which removing the organ with toxin is currently most certified.
Zhang Xiaonan, Xiaonan Zhang
openaire +4 more sources
The First Data on the Complete Genome of a Tetrodotoxin-Producing Bacterium
Toxins, 2021 Tetrodotoxin (TTX)-producing bacteria have attracted great interest as a model system for study of the TTX biosynthetic route. Here, we report the complete genome of the TTX-producing bacterium Bacillus sp. 1839.
Daria I. Melnikova +2 more
doaj +2 more sources
Confirmation and distribution of tetrodotoxin for the first time in terrestrial invertebrates: two terrestrial flatworm species (Bipalium adventitium and Bipalium kewense). [PDF]
PLoS ONE, 2014 The potent neurotoxin tetrodotoxin (TTX) is known from a diverse array of taxa, but is unknown in terrestrial invertebrates. Tetrodotoxin is a low molecular weight compound that acts by blocking voltage-gated sodium channels, inducing paralysis. However,
Amber N Stokes +7 more
doaj +2 more sources
Identifying environmental factors associated with tetrodotoxin contamination in bivalve mollusks using eXplainable AI [PDF]
npj Science of FoodSince 2012, tetrodotoxin (TTX) has been found in seafoods such as bivalve mollusks in temperate European waters. TTX contamination leads to food safety risks and economic losses, making early prediction of TTX contamination vital to the food industry and
M. C. Schoppema +6 more
doaj +2 more sources
An improved competitive inhibition enzymatic immunoassay method for tetrodotoxin quantification [PDF]
Biological Procedures Online, 2012 Quantifying tetrodotoxin (TTX) has been a challenge in both ecological and medical research due to the cost, time and training required of most quantification techniques.
Stokes Amber N +2 more
doaj +3 more sources
Tissue accumulation of tetrodotoxin (TTX) and analogues in trumpet shell Charonia lampas
Food Additives & Contaminants: Part A, 2022 Tetrodotoxin (TTX) is a potent neurotoxin responsible for a human intoxication event in Spain associated with the consumption of trumpet shell Charonia lampas. In Europe, TTX is not regulated or monitored, and there is little knowledge about its presence in seafood.
Lage, Sandra +4 more
openaire +5 more sources
Repurposing of thermally stable nucleic-acid aptamers for targeting tetrodotoxin (TTX). [PDF]
Comput Struct Biotechnol J, 2022 Tetrodotoxin (TTX) is a lethal neurotoxin produced by the endosymbiotic bacteria in the gut of puffer fish. Currently, there is no effective and economical method to detect TTX, so it is very interesting to develop low-cost and high-sensitivity detection methods by using nucleic-acid aptamers as the recognition molecules.
Li Y +5 more
europepmc +4 more sources
Marine Drugs, 2006 : Tetrodotoxin (TTX) is a highly specific blocker of voltage-gated sodium channels. The dissociation constant of block varies with different channel isoforms.
C. Ruben, Shana L. Geffeney
doaj +2 more sources
Tetrodotoxin Sensitivity of the Vertebrate Cardiac Na+ Current
Marine Drugs, 2011 Evolutionary origin and physiological significance of the tetrodotoxin (TTX) resistance of the vertebrate cardiac Na+ current (INa) is still unresolved.
Jaakko Haverinen +2 more
doaj +2 more sources
High Levels of Tetrodotoxin (TTX) in Trumpet Shell Charonia lampas from the Portuguese Coast. [PDF]
Toxins (Basel), 2021 Tetrodotoxin (TTX) is a potent neurotoxin, considered an emerging toxin in Europe where recently a safety limit of 44 µg TTX kg−1 was recommended by authorities. In this study, three specimens of the large gastropod trumpet shell Charonia lampas bought in a market in south Portugal were analyzed using a neuroblastoma cell (N2a) based assay and by LC-MS/
Costa PR +6 more
europepmc +7 more sources