Results 21 to 30 of about 17,066 (197)
From Poison to Promise: The Evolution of Tetrodotoxin and Its Potential as a Therapeutic
Toxins, 2021 Tetrodotoxin (TTX) is a potent neurotoxin that was first identified in pufferfish but has since been isolated from an array of taxa that host TTX-producing bacteria.
Gary M. Bucciarelli +5 more
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A Progress on the Application of Tetrodotoxin [PDF]
E3S Web of Conferences, 2021 Tetrodotoxin (TTX), a blocker of sodium channels, exists in the pufferfish, amphibians, and octopus, and originated in endosymbiont-vibrio. Researches have confirmed that TTX affected the action potential through the regulation of voltage-gated sodium ...
Wang Zhaojia, Zhou Zhenning
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The First Data on the Complete Genome of a Tetrodotoxin-Producing Bacterium
Toxins, 2021 Tetrodotoxin (TTX)-producing bacteria have attracted great interest as a model system for study of the TTX biosynthetic route. Here, we report the complete genome of the TTX-producing bacterium Bacillus sp. 1839.
Daria I. Melnikova +2 more
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An Overview of the Anatomical Distribution of Tetrodotoxin in Animals
Toxins, 2022 Tetrodotoxin (TTX), a potent paralytic sodium channel blocker, is an intriguing marine toxin. Widely distributed in nature, TTX has attracted attention in various scientific fields, from biomedical studies to environmental safety concerns. Despite a long
Daria I. Melnikova, Timur Yu. Magarlamov
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Marine Drugs, 2015 Tetrodotoxin (TTX), is a potent neurotoxin targeting sodium channels that has been identified in multiple marine and terrestrial organisms. It was recently detected in the Opisthobranch Pleurobranchaea maculata and a Platyhelminthes Stylochoplana sp ...
Lauren R. Salvitti +3 more
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Toxins, 2021 Nemertea is a phylum of marine worms whose members bear various toxins, including tetrodotoxin (TTX) and its analogues. Despite the more than 30 years of studying TTXs in nemerteans, many questions regarding their functions and the mechanisms ensuring ...
Anna E. Vlasenko +6 more
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Marine Drugs, 2012 Tetrodotoxin (TTX) is a potent neurotoxin that has been identified in a range of phylogenetically unrelated marine and terrestrial organisms. Tetrodotoxin was recently detected in New Zealand in Pleurobranchaea maculata (the grey side-gilled sea slug ...
Stephen Craig Cary +5 more
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Diversity and Biosynthetic Potential of Culturable Microbes Associated with Toxic Marine Animals
Marine Drugs, 2013 Tetrodotoxin (TTX) is a neurotoxin that has been reported from taxonomically diverse organisms across 14 different phyla. The biogenic origin of tetrodotoxin is still disputed, however, TTX biosynthesis by host-associated bacteria has been reported.
Brett A. Neilan +3 more
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Marine Drugs, 2011 Puffer fish, Takifugu niphobles, collected from the Hong Kong coastal waters were screened for tetrodotoxin-producing bacteria. A Gram-negative, non-acid-fast, non-sporing and rod shaped bacterial strain (designated as gutB01) was isolated from the ...
Fred Wang-Fat Lee +3 more
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An Updated Review of Tetrodotoxin and Its Peculiarities
Marine Drugs, 2022 Tetrodotoxin (TTX) is a crystalline, weakly basic, colorless organic substance and is one of the most potent marine toxins known. Although TTX was first isolated from pufferfish, it has been found in numerous other marine organisms and a few terrestrial ...
Panagiota Katikou +4 more
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