Results 101 to 110 of about 26,735 (204)
Tetrodotoxin: Chemistry, Toxicity, Source, Distribution and Detection
Toxins, 2014 Tetrodotoxin (TTX) is a naturally occurring toxin that has been responsible for human intoxications and fatalities. Its usual route of toxicity is via the ingestion of contaminated puffer fish which are a culinary delicacy, especially in Japan.
Vaishali Bane +4 more
doaj +1 more source
, 2018 A) Steps to different voltages (indicated) produced inward currents with at least two kinetically distinct components (2Ca solution, n = 6). The fast component was through voltage-gated Na+ channels as it was blocked by application of 1 μM TTX (n = 6 ...
Alexandra V. Ulyanova (5142920) +1 more
core +1 more source
Acute toxicity of tetrodotoxin (TTX). Should tetrodotoxin be part of the PSP class of toxins?
, 2019 Tetrodotoxin recognized as an emerging risk by international regulators Issues with TTX from pufferfish are well-known throughout history. TTX more recently identified in bivalve molluscs: -- Japan (scallops) -- NZ (pipi) -- UK (mussels and oysters ...
Sarah Finch (15395276)
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A Stereoselective Synthesis of (−)-Tetrodotoxin
, 2016 An asymmetric synthesis of the fugu fish poison, (−)-tetrodotoxin, is described. The route to this extraordinary target employs a number of unique transformations, foremost of which are two stereospecific C−H bond functionalization reactions. Accordingly,
Andrew Hinman (2993631) +1 more
core +1 more source
Marine DrugsTetrodotoxin (TTX) is a neurotoxin that binds to sodium channels and blocks sodium conduction. Importantly, TTX has been increasingly detected in edible aquatic organisms.
Xinxin Zhang +6 more
doaj +1 more source
Tetrodotoxin (TTX) is an extremely potent paralytic toxin responsible for yearly illness and death around the world. A clinical measurement is necessary to confirm exposure because symptoms of TTX intoxication cannot be distinguished from other paralytic
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Purification and Characterization of Tetrodotoxin-binding Substance in Shore Crab Hemolymph [PDF]
, 2001 P(論文)テトロドトキシン(TTX)は古くからフグ毒の主成分として知られる。1964年にカリフォルニアイモリの毒がTTXに同定されて以来,これまでに微生物から両生類にいたる多種の生物に存在することが明らかにされてきた。TTXは神経細胞のNaチャンネルを選択的にブロックして,神経の興奮を阻害する作用を持つ神経毒であるとされている。TTXを保有しない一般の硬骨魚類のTTXの腹腔内投与に対する抵抗性はマウスと同程度の体重20g当たり約1MUである。これに対して ...
楠田, 理一 +9 more
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Studies on Toxin-Producing Ability and Gene Map of Tetrodotoxin- Producing Bacteria
, 2010 [[abstract]]Tetrodotoxin (TTX) is one of the best known marine toxins, because of it’s an extremely potent, low-molecular weight, and non-protein neurotoxin. TTX exists with its several analogs.
Chun lan, Lin
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Drug binding sites on Nat1.8 sodium channels [PDF]
, 2008 The voltage-gated sodium channel, Nav 1.8, is known to play an important role in pain signalling. In this thesis, the functional properties and drug binding sites of wild type and mutant Nav 1.8 sodium channel currents were studied in mammalian sensory ...
Browne, Liam Edward
core +1 more source
Study of reproductive activity, maturity stages and tetrodotoxin (TTX) in yellow pufferfish, xenopterus naritus [PDF]
, 2016 This study was carried out in order to document the reproductive activity, maturity stages and tetrodotoxin (TTX) distribution in yellow pufferfish, Xenopterus naritus from Batang Saribas, Sarawak.
Herman Hermawan, Bakr i
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