Results 71 to 80 of about 543,834 (291)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

role of key words in comprehension of media texts

open access: yesДинамика медиасистем, 2021
The article gives an overview of the existing approaches on the problem of key words and their significance in text comprehension. It describes the levels of text comprehension, the differentiation between the terms ‘text meaning’ and ‘text sense ...
Анна Свиридова   +1 more
doaj  

A research on comprehension differences between print and screen reading

open access: yesSouth African Journal of Economic and Management Sciences, 2013
Since the 1980s, extensive research has been conducted comparing reading comprehension from printed text and computer screens. The conclusions, however, are not very consistent.
Szu-Yuan Sun   +2 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Processing Factors, Academic Discourse, and Local and Global Comprehension

open access: yesLanguage and Literacy: A Canadian Educational e-journal, 2013
The relationship among processing factors and the comprehension of literary and scientific discourses of fourth grade readers was examined. With one exception, a different matrix of processing behaviors were associated with the recall within the two ...
Stephen B Kucer
doaj   +1 more source

Text Comprehension

open access: yesInformation Design Journal, 2008
Short review of a theme issue of Applied Cognitive Psychology ...
openaire   +2 more sources

The relationship between appreciation of riddles and Chinese text comprehension in children [PDF]

open access: yes, 2011
The present study investigated (1) the role of riddle appreciation and reading accuracy in Chinese written text comprehension, and (2) relationship between different types of riddles and Chinese written text comprehension in 40 Cantonese-speaking ...
Tang, Nga-yee, Ivy, 鄧雅怡
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

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