Results 51 to 60 of about 7,691 (171)

Disruption of iron metabolism resulting from Dmt1/Slc11a2 deficiency compromises Notch protein degradation and transcriptional activation

open access: yesThe FEBS Journal, EarlyView.
Divalent metal transporter 1 (Dmt1) maintains iron homeostasis and lysosomal proteostasis required for physiological Notch receptor–ligand signaling. Dmt1 loss lowers iron storage capacity (ferritin), increasing intracellular Fe2+, driving ROS and lipid peroxidation, and leading to lysosomal/mitochondrial dysfunction.
Rui Zhang   +5 more
wiley   +1 more source

Trends in Irish Fertility Rates in Comparative Perspective [PDF]

open access: yes
This paper examines trends in Irish fertility rates over the past four decades in the context of fertility trends in developed countries generally. Irish fertility rates have stabilised at the upper edge of the European range in the 1990s.
Tony Fahey
core  

IL‐2 silencing enables Tfh cell expansion during vaccination but is redundant for antibody production

open access: yesImmunology &Cell Biology, EarlyView.
Sustained IL‐2 production delays T follicular helper cell differentiation and germinal center formation but does not alter final antibody titers or antigen‐specific humoral immunity after vaccination. Created in BioRender. Burton, A. (2026) https://BioRender.com/paggz41 Abstract Vaccines stimulate protective humoral immunity by coordinating lymphocyte ...
Silvia Innocentin   +9 more
wiley   +1 more source

Vintage specific learning-by-doing [PDF]

open access: yes
This paper focuses on timing of fertility decisions, conditional on the level of educational attainment of parents. Timing of fertility and educational attainment of parents rationalize the negative relationship observed in the data between hourly wages ...
Juan Carlos Conesa
core   +1 more source

TEAM‐UP: Mixed‐Methods Data for Understanding Traditional and Modern Contraceptive Use Dynamics in Four Sub‐Saharan African Countries

open access: yesStudies in Family Planning, EarlyView.
Abstract This Data Article describes a novel dataset from the “Re‐Examining Traditional Method Use” (TEAM‐UP) project, which systematically collected data on the measurement of and motivations for use of non‐modern (traditional and folkloric) contraceptive methods and/or modern methods, in four sub‐Saharan African countries: the Democratic Republic of ...
Nurudeen Alhassan   +13 more
wiley   +1 more source

The Contribution of Educational Changes to Fertility Declines in Low‐ and Middle‐Income Countries

open access: yesStudies in Family Planning, EarlyView.
Abstract Educational expansion is widely regarded as a central mechanism in fertility transitions, yet some research suggests its role may be more modest. This study analyzes birth histories from 414 surveys in 72 low‐ and middle‐income countries to reassess the contribution of the shift in the educational composition of the population to fertility ...
Bruno D. Schoumaker   +1 more
wiley   +1 more source

Protein design and RNA design: Perspectives

open access: yesQuantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley   +1 more source

Advanced aircraft engine materials trends [PDF]

open access: yes
Recent activities of the Lewis Research Center are reviewed which are directed toward developing materials for rotating hot section components for aircraft gas turbines.
Dreshfield, R. L.   +3 more
core   +1 more source

Mixed Signals: T Cells as Architects of IgE Immunity

open access: yesImmunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Food allergen‐specific IgE can cause significant pathology, yet the pathways that generate pathogenic, high‐affinity IgE remain incompletely understood. Increasing evidence suggests that IgE responses arise from the integration of multiple, and sometimes opposing, T cell–derived cues.
Abigail L. Tierney   +3 more
wiley   +1 more source

Evolution of the infrared Tully-Fisher relation up to z=1.4

open access: yes, 2010
The Tully-Fisher relation (TFR) represents a connection between fundamental galaxy parameters, such as its total mass and the mass locked in stars. Therefore, the study of the evolution of this relation in the optical and infrared bands can provide ...
A. Bongiovanni   +66 more
core   +1 more source

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