Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao +8 more
wiley +1 more source
Regulation of TGF-β and BMP Signaling by Natural Triterpene Compounds in Pulmonary Arterial Hypertension (PAH). [PDF]
Sener SO +6 more
europepmc +1 more source
GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh +8 more
wiley +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF-β signaling. [PDF]
Li C +3 more
europepmc +1 more source
Fibroblast TGF-β signaling defines spatial tumor ecosystems linked to immune checkpoint blockade resistance. [PDF]
Lee SY, Lee Y.
europepmc +1 more source
Galunisertib attenuates pulmonary fibrosis with silicosis in mouse via TGF-β/TRAF6/Beclin1 signaling pathway. [PDF]
Li R +6 more
europepmc +1 more source
CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells. [PDF]
Matsunuma R +5 more
europepmc +1 more source
CKD-Induced Oxidative Twitch Muscle Atrophy Is Mediated by TGF- β. [PDF]
Homma K +3 more
europepmc +1 more source
CTHRC1/TGF-β/Smad axis serves as therapeutic targets in inhibiting oral squamous cell carcinoma by mediating ferroptosis. [PDF]
Huang S +5 more
europepmc +1 more source

