Results 181 to 190 of about 239,501 (262)

Chlorogenic Acid Attenuates Bleomycin-Induced Pulmonary Fibrosis in a Murine Model by Modulating TGF-β1 Expression. [PDF]

Adv Respir Med
Velázquez-Enríquez JM, Ramírez-Hernández AA, Santos-Álvarez JC, Reyes-Jiménez E, Arcos-Román A, Arellanes-Robledo J, Matias-Cervantes CA, Pina-Canseco MDS, Vásquez-Garzón VR, Baltiérrez-Hoyos R.   +9 more
europepmc   +1 more source

Heat stress in spermatogenesis: a redox‐dependent decision network linking ROS, autophagy, and regulated cell death

Biological Reviews, EarlyView.
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley   +1 more source

Matching TGF-β1 Activation With Stress-Responsive Charge-Reversal Hydrogel Microspheres for the Treatment of Osteoarthritis. [PDF]

Exploration (Beijing)
Lin F, Xu Y, Xiang L, Zhu Y, Li Y, Zhuang Y, Zhang Z, Chen J, Kang H, Zhang N, Yu X, Cui W.   +11 more
europepmc   +1 more source

Halogenated Tryptophans Improve Integrin αVβ6 Affinity of Cyclic RGD Peptides and Provide Handles for Late‐Stage Derivatization

Chemistry – A European Journal, EarlyView.
Lighting up αVβ6: Halotryptophan engineering converts an RGD scaffold into a modular αVβ6 ligand platform, enabling picomolar affinity and late‐stage functionalization. The resulting probes combine high selectivity with fluorescence for FACS and tumor imaging.
Beate Nachtigall, Caroline Brinkmann, Jana Langosch, Anke Nieß, Norbert Sewald   +4 more
wiley   +1 more source

A novel positive feedback regulatory loop, TGF-β1/SMAD4/miR-184, controls the follicular development in sows. [PDF]

Zool Res
Li QQ, Lu HY, Luo C, Guo ZN, Shi XL, Shan BS, Wang SF, Li QF, Du X.   +8 more
europepmc   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

Critical role for the TGF-β1/mTORC1 signaling axis in defining the transcriptional identity of CTHRC1⁺ pathologic fibroblasts. [PDF]

Sci Adv
Wilson JA, Walters R, Contento G, Rossanese M, Guillotin D, Ward AI, Hynds RE, Jamal-Hanjani M, Kaminski N, Parolo S, Platé M, Chambers RC.   +11 more
europepmc   +1 more source

Review of articular cartilage repair techniques and their application in the horse

Equine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton, Brad B. Nelson, Laurie R. Goodrich   +2 more
wiley   +1 more source

Engineering RVG-modified exosomes for targeting TGF-β1 signaling in stroke recovery. [PDF]

J Transl Med
Zhao W, Hao L, Zhang J, Zhu J, Kuang J, Zhang M, Zhang Y, Xiong X, Yang Z.   +8 more
europepmc   +1 more source

The influence of a systemic non‐steroidal anti‐inflammatory drug on growth factors and cytokines in equine plasma, solid platelet‐rich fibrin (PRF), and liquid PRF

Equine Veterinary Journal, EarlyView.
Abstract Background Platelet‐rich fibrin (PRF) is a second‐generation platelet concentrate that contains growth factors and cytokines within a fibrin matrix, allowing prolonged release and supporting its use as a regenerative therapy for corneal wound healing.
Katrina E. V. Jones, Kimberly Young, Erin Barr, Chongben Zhang, Cody McGrath, Kimberly R. Love, Brian Gilger, Michala de Linde Henriksen   +7 more
wiley   +1 more source