Results 201 to 210 of about 202,654 (267)

Extracellular Vesicle‐Based Therapies for Osteoarthritis—Advances, Challenges and Hopes

Exploration, EarlyView.
Recent advances, challenges and hopes in using extracellular vesicles (EVs) as therapeutics for osteoarthritis. Recent advances include native and engineered EVs and translational developments. Challenges include cell sources and targeted effects of EVs, as well as establishing robust critical quality attributes, while hopes for advancing this field ...
Jiao Jiao Li, Wei Seong Toh
wiley   +1 more source

Oleuropein attenuates cardiac fibrosis via modulation of TGF-β1/Smad pathway in diabetic cardiomyopathy rat model. [PDF]

Sci Rep
Abdelrauf LM, Habashy DA, Sharaf NM, El-Shafei AA, Kassem L, Abdelghany RM.   +5 more
europepmc   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

The miR-16-1-3p suppresses proliferation and invasiveness via the MDM2-p53 axis in TGF-β1 signaling in osteosarcoma. [PDF]

Mol Ther Oncol
Xue W, Wang Y, Smirnova AV, Malakhov PA, Pustovalova M, Kuzmin DV, Leonov S.   +6 more
europepmc   +1 more source

Dual Specificity Phosphatase 4 Enhances Immunotherapy Response by Inhibiting TGF-β1 Secretion in Hepatocellular Carcinoma. [PDF]

Cancers (Basel)
Su LP, Wang WY, Ma XD, Hao SH.
europepmc   +1 more source

Acupotomy Ameliorates Articular Cartilage Fibrosis in a Rabbit Model of Knee Osteoarthritis via the TGF-β1/Smad Pathway. [PDF]

Orthop Res Rev
Xing L, Zhu W, Chen X, Che R, Wu J, Guo Y, Liang C.   +6 more
europepmc   +1 more source

Dapagliflozin attenuates diabetic renal fibrosis by inhibiting macrophage-myofibroblast transition <i>via</i> the TGF-β1-Smad3/7 pathway. [PDF]

PeerJ
Li X, Yao G, Wang H, Zhao T, Sun Y, Gao Q, Li Z, Chen B.   +7 more
europepmc   +1 more source

CILP attenuates pulmonary fibrosis through the TGF-β1/SMAD3 pathway. [PDF]

Eur J Med Res
Zou H, Dong J, Zhao R, Liu F, Cheng J, Li X, Fei C, Li P, Liu C.   +8 more
europepmc   +1 more source

Selective blockade of latent TGF-β1 activation suppresses tissue fibrosis with good safety. [PDF]

Commun Med (Lond)
Kanamori M, Sato I, Koo CX, Sun Y, Kawauchi H, Nakagawa K, Murai A, Asanuma K, Gan SW, Pang CL, Shimizu Y, Shida-Kawazoe M, Kanamaru C, Kayukawa Y, Hada N, Ohmine K, Kitazawa T, Nezu J, Igawa T, Shimada H.   +19 more
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source