Transforming growth factor β1 inhibition protects from noise-induced hearing loss [PDF]
Excessive exposure to noise damages the principal cochlear structures leading to hearing impairment. Inflammatory and immune responses are central mechanisms in cochlear defensive response to noise but, if unregulated, they contribute to inner ear damage
Silvia eMurillo-Cuesta +19 more
doaj +5 more sources
Role of transforming growth factor-β1 in breast carcinogenesis [PDF]
The main objective of this presentation is to review current knowledge regarding molecular mechanisms of Transforming Growth Factor-β1(TGF-ß1) action in breast carcinogenesis.
Ivanović Vesna +3 more
doaj +3 more sources
Role of transforming growth factor-β1 in regulating adipocyte progenitors [PDF]
Adipose tissue (AT) metabolism involves coordinating various cells and cellular processes to regulate energy storage, release, and overall metabolic homeostasis. Therein, macrophage and its cytokine are important in controlling tissue homeostasis.
Nguyen Quynh Phuong +19 more
doaj +2 more sources
Comparison of Transforming Growth Factor-Beta 1 Concentration in Preeclampsia and Normal Pregnancy Women [PDF]
BACKGROUND: According to the theory of endothelial dysfunction, the pathogenesis of preeclampsia is associated with the imbalance of angiogenic and anti-angiogenic factors.
Yusrawati Yusrawati +2 more
doaj +2 more sources
Corrigendum to: Transforming growth factor β1 inhibition protects from noise-induced hearing loss
Unfortunately, the second author affiliation in the originally published article was incorrectly stated as being “Centre for Biomedical Network Research (CIBER), Institute of Health Carlos III (ISCIII), Madrid, Spain.” The correct author's affiliation is “Centre for Biomedical Network Research on Rare Diseases (CIBERER), Institute of Health Carlos ...
Silvia eMurillo-Cuesta +19 more
doaj +4 more sources
Empagliflozin attenuates ventricular fibrillation postmyocardial infarction associated with reduced transforming growth factor-1/Smad3 signaling and miR-181a expression [PDF]
Objective To determine whether empagliflozin reduces ventricular fibrillation and myocardial fibrosis after myocardial infarction via the transforming growth factor-β1/Smad3/miR-181a pathway.
Jingsong Shen +8 more
doaj +2 more sources
Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells. [PDF]
Epithelial-to-mesenchymal transition (EMT) plays a critical role in cancer metastasis, and is regulated by growth factors such as transforming growth factor β (TGF-β) and fibroblast growth factors (FGF) secreted from the stromal and tumor cells. However,
Hamada, Yoshinosuke +7 more
core +10 more sources
Transforming Growth Factor-β1 T869C Gene Polymorphism Is Associated with Acquired Sick Sinus Syndrome via Linking a Higher Serum Protein Level. [PDF]
Familial sick sinus syndrome is associated with gene mutations and dysfunction of ion channels. In contrast, degenerative fibrosis of the sinus node tissue plays an important role in the pathogenesis of acquired sick sinus syndrome.
Jan-Yow Chen +5 more
doaj +1 more source
Background: To study the expressions of transforming growth factor-β1 (TGF-β1) and vascular endothelial growth factor (VEGF) in patients with acute myeloid leukemia (AML) and their values for prognosis.
Xu Yan, Yu Xianqiu, Zhang Xinlong
doaj +1 more source
Correlation of Expression Transforming Growth Factor-β1, E-cadherin, and Ki-67 in Meningiomas
BACKGROUND: Meningioma is the most common primary intracranial tumors in adults, accounts for 36% of total intracranial tumors. Obtaining the clinicopathological characteristics of patients with meningioma and investigating, the association between signaling pathways with disease progression could provide a basis for therapeutic development.AIM: This ...
Apriyanto, Apriyanto +3 more
openaire +2 more sources

