Results 41 to 50 of about 9,299,804 (276)

LUAS DEFEK MENINGOKEL BERHUBUNGAN DENGAN KADAR TRANSFORMING GROWTH FACTOR β1 (TGF-β1)DAN INSULINE-LIKE GROWTH FACTOR-1 (IGF-1) DALAM TULANG

Jurnal Kedokteran Brawijaya, 2013
Meningocele pathogenesis is based on skull defect that occurs since the first three month of fertilization period. Through that defect, mening, cerebrospinal liquid, and cerebral parenchym is protruded. Meningocele can cause by folic aciddeficiency that had proved correlation with TGF-β1 and IGF-I level, both in maternal blood or baby rat’s skull.
openaire   +2 more sources

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Endogenous transforming growth factor β1 suppresses inflammation and promotes survival in adult CNS [PDF]

, 2007
Transforming growth factor β1 (TGFβ1) is a pleiotropic cytokine with potent neurotrophic and immunosuppressive properties that is upregulated after injury, but also expressed in the normal nervous system.
Bauer, K, Koppius, A, Makwana, M, Cuthill, D, Ormsby, I, Jones, LL, Bueringer, D, Friedrichsen, S, Hristova, M, Heuer, H, Bohatschek, M, Doetschman, T, Raivich, G   +12 more
core  

Connective tissue growth factor antagonizes transforming growth factor-β1/Smad signalling in renal mesangial cells

, 2011
The critical involvement of TGF-β1 (transforming growth factor-β1) in DN (diabetic nephropathy) is well established. However, the role of CTGF (connective tissue growth factor) in regulating the complex interplay of TGF-β1 signalling networks is poorly ...
John Crean, Kavanagh, David H, Kavanagh, David H., Fionnuala Hickey, David H. Kavanagh, Catherine Godson, Godson, Catherine, Noelynn Oliver, O'Donovan, Helen C, Crean, John, Brazil, Derek P, Derek P. Brazil, Finian Martin, Helen C. O'Donovan, Hickey, Fionnuala, Martin, Finian, Oliver, Noelynn, Brazil, Derek P., O'Donovan, Helen C.   +18 more
core   +1 more source

Effect of freeze-drying process of collagen-activated platelet-rich plasma on transforming growth factor-β1 level

Majalah Kedokteran Gigi Indonesia, 2019
Periodontal tissue damage requires regenerative material to repair the damage. Platelet-rich plasma (PRP) is known as a regenerative material from blood which contains high level of growth factor that plays a role in wound healing and tissue remodeling ...
Kwartarini Murdiastuti, Fitri Yuniawati, Dahlia Herawati, Nunuk Purwanti, Dyah Ayu Mira Oktarina   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Role of Transforming Growth Factor-β1 in Invasion and Metastasis in Gastric Carcinoma

, 1999
PURPOSE: Transforming growth factor-beta1 (TGF-β1) is a major modulator of cellular proliferation and extracellular matrix formation. We determined the role of TGF-β1 in invasion and metastasis in gastric cancer.
Yasunori Emi, Yoshihiro Kakeji, Hideo Baba, Yoshihiko Maehara, Akira Kabashima, Shunji Kohnoe, Akihiro Watanabe, Keizo Sugimachi, Kohei Akazawa   +8 more
core   +1 more source

Effects of 530 nm monochromatic light on basic fibroblast growth factor and transforming growth factor-β1 expression in Müller cells [PDF]

, 2015
AIM: To expose rat retinal Müller cells to 530 nm monochromatic light and investigate the influence of varying light illumination times on basic fibroblast growth factor (bFGF) and transforming growth factor-β1 (TGF-β1) expression.METHODS: Three groups ...
Xin-Yi Fu, Zheng-Tai Sun, Wei Xia, Xiao-Feng Zhang, Lei Zhong, Ying-Ming Wang, Jing Xia   +6 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Quantification of Platelet Counts and Growth Factor Profiling (TGF-β1, PDGF-BB, VEGF-A) Across Distinct Canine Platelet Concentrate Preparations [PDF]

This scientific database compiles quantitative data on platelet concentrations and growth factor levels in various platelet-derived products obtained from healthy Beagle dogs. Specifically, it includes platelet counts (expressed as x10³ platelets/μL) and
franch, jordi, Montolío, Marta, Herrera Bejarano, David, Roque, Anita Isabel, Montolio Torrell, Marta M.   +4 more
core   +1 more source