Results 41 to 50 of about 142,698 (173)
Preparation and functional identification of anti-human transforming growth factor β1 nanobodies [PDF]
Objective To prepare alpaca-derived anti-human TGF-β1 nanobodies with high specificity and high affinity. Methods The eukaryotic expression plasmid cFUGW-TGF-β1 was constructed and transiently transfected into HEK-293T cells to obtain recombinant TGF-β1 ...
WANG Yue, LI Zheng, CHEN Hui, ZHANG Jian-min, HE Wei
doaj
Possible Consequences for TGF-β1 Signaling [PDF]
Glycosaminoglycans are known to bind biological mediators thereby modulating their biological activity. Sulfated hyaluronans (sHA) were reported to strongly interact with transforming growth factor (TGF)-β1 leading to impaired bioactivity in ...
Koehler, Linda +6 more
core +1 more source
Periodontal tissue damage requires regenerative material to repair the damage. Platelet-rich plasma (PRP) is known as a regenerative material from blood which contains high level of growth factor that plays a role in wound healing and tissue remodeling ...
Kwartarini Murdiastuti +4 more
doaj +1 more source
Endogenous transforming growth factor β1 suppresses inflammation and promotes survival in adult CNS [PDF]
Transforming growth factor β1 (TGFβ1) is a pleiotropic cytokine with potent neurotrophic and immunosuppressive properties that is upregulated after injury, but also expressed in the normal nervous system.
Bauer, K +12 more
core
EGF and TGF-β1 effects on thyroid function [PDF]
Normal epithelial thyroid cells in culture are inhibited by TGF-β1. Instead, transformed thyroid cell lines are frequently resistant to its growth inhibitory effect. Loss of TGF-β responsiveness could be due to a reduced expression of TGF-β receptors, as
Gabriella Mincione +7 more
core +2 more sources
Supplementary information containing Table S1. presenting primer sequences used for real-time PCR, and Table S2. presenting the characterization of epithelial to myofibroblast/ myofibroblast-like cell transdifferentiation in 36 articles. (PDF 487 kb)
Haisheng Li +12 more
openaire +1 more source
Effects of TGF-β1 and IGF-1 on proliferation of human nucleus pulposus cells in medium with different serum concentrations [PDF]
Background The low proliferative viability of human nucleus pulposus(NP) cells is considered as a cause of intervertebral discs degeneration. Growth factors, such as TGF-β1 and IGF-1, have been implicated in cell proliferation and matrix synthesis ...
Rongfeng Zhang +19 more
core +1 more source
Supplementary material, approximately 723 KB.
Nicolini, Giuseppina +5 more
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Introduction: Marfan syndrome is a rare disease in which different metabolic pathways and immune mediators such as transforming growth factor β1, interleukins and metalloproteinases participate.
María Elena Soto +8 more
doaj +1 more source
Biological activity differences between TGF-β1 and TGF-β3 correlate with differences in the rigidity and arrangement of their component monomers [PDF]
[Image: see text] TGF-β1, -β2, and -β3 are small, secreted signaling proteins. They share 71–80% sequence identity and signal through the same receptors, yet the isoform-specific null mice have distinctive phenotypes and are inviable.
Andrew P. Hinck +61 more
core +2 more sources

