Results 31 to 40 of about 142,698 (173)

Type-1 Collagen differentially alters β-catenin accumulation in primary Dupuytren's Disease cord and adjacent palmar fascia cells

BMC Musculoskeletal Disorders, 2009
Background Dupuytren's Disease (DD) is a debilitating contractile fibrosis of the palmar fascia characterised by excess collagen deposition, contractile myofibroblast development, increased Transforming Growth Factor-β levels and β-catenin accumulation ...
Gan Bing, Wu Yan, Njarlangattil Anna, Vi Linda, O'Gorman David B   +4 more
doaj   +1 more source

Evaluation of TGF-β1 and MCP-1 expression and tubulointerstitial fibrosis in children with Henoch-Schönlein purpura nephritis and IgA nephropathy: A clinical correlation

Clinics
OBJECTIVES: Henoch-Schönlein purpura nephritis and immunoglobulin A nephropathy are two diseases with similar clinical presentations but very different prognoses.
Zhao Shuiai, Shen Huijun, Gu Weizhong, Liu Aimin, Mao Jianhua   +4 more
doaj   +1 more source

Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis [PDF]

, 2018
Objectives: Cellular energy metabolism is important for the function of all tissues, including cartilage. Recent studies indicate that superficial and deep subpopulations of articular chondrocytes (ACs) have distinct metabolic profiles.
O\u27Keefe, Regis J, Shen, Jie, Silverman, Richard M, Wang, Cuicui   +3 more
core   +3 more sources

LUAS DEFEK MENINGOKEL BERHUBUNGAN DENGAN KADAR TRANSFORMING GROWTH FACTOR β1 (TGF-β1)DAN INSULINE-LIKE GROWTH FACTOR-1 (IGF-1) DALAM TULANG

Jurnal Kedokteran Brawijaya, 2013
Meningocele pathogenesis is based on skull defect that occurs since the first three month of fertilization period. Through that defect, mening, cerebrospinal liquid, and cerebral parenchym is protruded. Meningocele can cause by folic aciddeficiency that had proved correlation with TGF-β1 and IGF-I level, both in maternal blood or baby rat’s skull.
openaire   +2 more sources

Marein alleviates myocardial fibrosis in diabetic mice [PDF]

Jichu yixue yu linchuang
Objective To study the effect of marein on myocardial fibrosis in diabetic mice. Methods Ten leptin receptor gene defective heterozygous (db/m) mice aged 5-6 weeks were selected as the control group and 30 diabetic mice with leptin receptor gene ...
TIAN Yating, ZHANG Fang, ZHANG Boxiang, LI Tian
doaj   +1 more source

Pathogenetic significance of transforming growth factor β1 in patients with colorectal cancer

Фундаментальная и клиническая медицина, 2022
Aim. We aimed to evaluate levels of transforming growth factor β1 (TGF-β1) in the serum, lymph nodes, and primary tumour in patients with colorectal cancer.Materials and Methods.
A. V. Chetveryakov, V. L. Tsepelev
doaj   +1 more source

MOESM1 of Transforming Growth Factor-β1 Downregulates Vascular Endothelial Growth Factor-D Expression in Human Lung Fibroblasts via the Jun NH2-Terminal Kinase Signaling Pathway

, 2014
Supplementary material, approximately 700 KB.
Cui, Ye, Osorio, Juan, Risquez, Cristobal, Wang, Hao, Shi, Ying, Gochuico, Bernadette, Morse, Danielle, Rosas, Ivan, El-Chemaly, Souheil   +8 more
openaire   +1 more source

Transforming growth factor-β1/Smad/connective tissue growth factor axis: The main pathway in radiation-induced fibrosis of osteoradionecrosis?

Dental Hypotheses, 2013
Introduction: Osteoradionecrosis (ORN) of the mandible is a serious complication following radiation therapy for malignancies of the head and neck. Radiation-induced fibrosis (RIF) is a new theory that accounts for the damage to normal tissues after ...
Qian Wei Zhuang, Zhi Yuan Zhang, Guang Long Liu, Shui Ting Fu, Yue He   +4 more
doaj   +1 more source

Integrin control of the transforming growth factor-β pathway in glioblastoma [PDF]

, 2017
Transforming growth factor-β is a central mediator of the malignant phenotype of glioblastoma, the most common and malignant form of intrinsic brain tumours.
Goodman, Simon L., Hasenbach, Kathy, Maurer, Gabriele, Moch, Holger, Roth, Patrick, Schraml, Peter, Silginer, Manuela, Tabatabai, Ghazaleh, Thies, Svenja, Tritschler, Isabel, Weller, Michael   +10 more
core  

Additional file 1: of Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-β1

, 2016
Additional methods.
Hahn, Jennifer, McFarland, Kevin, Combs, Kelly, Supp, Dorothy   +3 more
openaire   +1 more source