Results 21 to 30 of about 142,698 (173)

A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β1 pathways [PDF]

, 2017
Renal fibrosis is closely related to chronic inflammation and is under the control of epigenetic regulations. Because the signaling of transforming growth factor-β1 (TGF-β1) and tumor necrosis factor-α (TNF-α) play key roles in progression of renal ...
Abe, Takaaki, Akiyama, Yasutoshi, Akiyama, Yukako, Hayashi, Ken-ichiro, Ho, Hsin-Jung, Ito, Sadayoshi, Kikuchi, Koichi, Kobayashi, Takayasu, Masaki, Takao, Masamune, Atsushi, Matsuhashi, Tetsuro, Matsuo, Akihiro, Mishima, Eikan, Mukawa, Chikahisa, Nanto, Fumika, Oba, Yuki, Obara, Ten, Oikawa, Yoshitsugu, Saigusa, Daisuke, Sasaki, Kensuke, Shima, Hisato, Suzuki, Chitose, Suzuki, Takehiro, Tomioka, Yoshihisa, Watanabe, Shun   +24 more
core   +1 more source

Evaluation of rs1982073 polymorphism of transforming growth factor-β1 in glioblastoma

Journal of Research in Medical Sciences, 2019
Background: Glioblastoma (GBM) is the most common and invasive form of primary malignant brain tumors, with a survival rate of about 1 year. Transforming growth factor-β1 (TGF- β 1) plays a very important role in tissue homeostasis and cancers.
Yasaman Sadeghi, Pouya Tabatabaei Irani, Laleh Rafiee, Mohamadhasan Tajadini, Alireza Amouheidari, Shaghayegh Haghjooy Javanmard   +5 more
doaj   +1 more source

Kadar Transforming Growth Factor β-1 Urin pada Berbagai Keadaan Proteinuria

Sari Pediatri, 2019
Latar belakang. Proteinuria masif pada sindrom nefrotik (SN) akan menginduksi suatu rentetan reaksi biologis di tubular proksimal. Reaksi ini mengaktivasi peptida vasoaktif dan produksi sitokin, seperti TGF-β1.
Partini P. Trihono, Husein Alatas, Taralan Tambunan, Sudigdo Sastroasmoro   +3 more
doaj   +1 more source

High glucose-induced Matrilin-2 expression in mouse mesangial cells was mediated by transforming growth factor beta 1 (TGF-β1) [PDF]

, 2016
This study aimed at evaluating the effect of high glucose on the expression of extracellular matrix (ECM) protein Matrilin-2 and the mechanism underlying this effect by using a mouse mesangial cell line.
Du, Yanshneg, Huang, Hong, Luo, Junming, Yi, Xin, Zhang, Menglan, Zhang, Shukun, Zhou, Shiying   +6 more
core   +1 more source

Serum Homocysteine, VEGF and TGF-β1 dynamic change in colorectal cancer patients prior and post-operation

Pteridines, 2019
Background: The aim of the study was to evaluate the serum homocysteine (Hcy), vascular endothelial growth factor (VEGF) and transforming growth factor β1 (TGF-β1) dynamic change in colorectal cancer patients pre- and post-operation.
Ni Yayi, Xue Lihua, Zhu Guangbo, Chen Yangrong   +3 more
doaj   +1 more source

Transforming Growth Factor β1 and Tropoelastin Expression in Uterine Prolapse

Indonesian Journal of Obstetrics and Gynecology, 2016
Objective: To know the correlation of the expression of transforming growth factor beta (TGF-β1) and tropoelastin in uterine prolapse. Method: A cross-sectional study of 30 subjects suffered from uterine prolapse in the Department of Obstetrics and ...
Alvilusia Alvilusia, Amir Fauzi, Azhari Azhari, Wresnindyatsih Wresnindyatsih, Irsan Saleh   +4 more
doaj   +1 more source

Differential Quantitative Proteomics of Human Microvascular Endothelial Cells 1 by iTRAQ Reveals Palladin to be a New Biomarker During TGF-β1 Induced Endothelial Mesenchymal Transition [PDF]

, 2017
The study uses global quantitative proteomics to investigate the molecular mechanisms behind the induction of endothelial-mesenchymal transition (EndMT) by transforming growth factor–β (TGF-β).
Bednarek, Radosław, Gawryś, Katarzyna, Popielarsk, Marcin, Sitkiewicz, Ewa, Stasiak, Marta, Studzian, Maciej, Swiatkowska, Maria, Szemraj, Janusz   +7 more
core   +1 more source

Effect of Sini decoction on angiotensin II, transforming growth factor β1 and connective tissue growth factor in rats with myocardial fibrosis-induced banding of the abdominal aorta

Journal of Traditional Chinese Medicine, 2018
To investigate the effect of Sini decoction on rats with myocardial fibrosis induced by banding the abdominal aorta, and explore the mechanism underlying its actions on angiotensin ¢ò(Ang ¢ò), transforming growth factor-¦Â1 (TGF-¦Â1) and connective tissue growth factor (CTGF).Forty-eight male Sprague-Dawley rats were randomly divided into sham ...
Yueping, Shi, Chunxiao, Liu, Jianli, Zhai   +2 more
openaire   +2 more sources

Clinical Relevance of Transforming Growth Factor-β1, Interleukin-6 and Haptoglobin for Prediction of Obesity Complications in Prepubertal Egyptian Children

Open Access Macedonian Journal of Medical Sciences, 2015
BACKGROUND: The rate of obesity is increasing throughout the world. Obesity in adults’ research is characterized by chronic inflammation, associated with type 2 Diabetes and cardiovascular risk. The degree to which these changes occur in childhood obesity is not fully defined.AIM: This study was designed to explore the relation between circulating ...
El-Alameey, Inas R., Fadl, Nevein N., Abdel Hameed, Enas R., Sherif, Lobna S., Ahmed, Hanaa H.   +4 more
openaire   +4 more sources

Age-Related Changes of Transforming Growth Factor β1 in Japanese Children

Allergology International, 2009
Background: Transforming growth factor β1 (TGFβ1) is an important factor in immunomodulation. The expression of TGFβ1 has been shown to be influenced by the C-509 T polymorphism in the TGFβ1 gene.
Masahiro Morimoto, Eiko Matsui, Norio Kawamoto, Satomi Sakurai, Hideo Kaneko, Toshiyuki Fukao, Shinichi Iwasa, Makoto Shiraki, Kimiko Kasahara, Naomi Kondo   +9 more
doaj   +1 more source