Expression of P-selectin, TXA2, TGF-β1 and PDGF-AB in the Presence of Bioadhesive Chitosan Derivatives [PDF]
, 2014 Chitosan is a natural macromolecular polysaccharide, derived from chitin extracted from the exoskeleton of some marine invertebrates. This study was designed to evaluate the expression of P-selectin, thromboxane A2 (TXA2), transforming growth factor-β1
Abdul Rashid, Ahmad Hazri +5 more
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Journal of the Formosan Medical Association, 2018 Background/Purpose: Many fibrotic processes are associated with an increased level of transforming growth factor-β1 (TGF-β1). TGF-β1 can increase synthesis of matrix proteins and enhance secretion of protease inhibitors, resulting in matrix accumulation.
Jung-Tsu Chen +2 more
doaj +1 more source
Catalase Prevents Maternal Diabetes–Induced Perinatal Programming via the Nrf2–HO-1 Defense System [PDF]
, 2014 We investigated whether overexpression of catalase (CAT) in renal proximal tubular cells (RPTCs) could prevent the programming of hypertension and kidney disease in the offspring of dams with maternal diabetes.
Chang, Shiao-Ying +7 more
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Cellular Physiology and Biochemistry, 2015 Background/Aims: Severe acute lung injury (ALI) often develops into acute respiratory distress syndrome (ARDS). Previous studies have shown that platelet-derived growth factor (PDGF) and transforming growth factor β1 (TGFβ1) participate in the ...
Xingqi Deng +5 more
doaj +1 more source
Biofunctionalised electrospun scaffolds for cartilage tissue engineering
, 2011 The field of tissue engineering has advanced and evolved to focus on biomimetic strategies to meet the rise in demands of tissue replacements for surgical reconstruction.
Lim, Erh-Hsuin, Lim, Erh-Hsuin
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HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes [PDF]
, 2010 Histone deacetylases (HDACs) regulate the acetylation of histones in the control of gene expression. Many non-histone proteins are also targeted for acetylation, including TGF-ß signalling pathway components such as Smad2, Smad3 and Smad7. Our studies in
Andrew D. Rowan +54 more
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Neurobiology of Disease, 2006 Communicating hydrocephalus may occur spontaneously in elderly patients or occur as a complication of meningitis or intracranial hemorrhage, typically as a result of fibrosis along the route of cerebrospinal fluid (CSF) flow.
Tsuyoshi Tada +5 more
doaj +1 more source
Hepatocyte growth factor mediates enhanced wound healing responses and resistance to transforming growth factor-β1-driven myofibroblast differentiation in oral mucosal fibroblasts [PDF]
, 2017 Oral mucosal wounds are characterized by rapid healing with minimal scarring, partly attributable to the “enhanced” wound healing properties of oral mucosal fibroblasts (OMFs). Hepatocyte growth factor (HGF) is a pleiotropic growth factor, with potential
Charalambous, Chrisandrea +8 more
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Role of TGFbRII in myeloid cell mediated regenerative processes and fibroplasia [PDF]
, 2012 Tissue repair and fibrosis are controlled by the interaction of different cell lineages, their soluble factors and matrix signals. Recently, macrophages have been found to be crucial for proper tissue repair.
Ranjan, Rajeev
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Polymorphism in TGFB1 is associated with worse non-relapse mortality and overall survival after stem cell transplantation with unrelated donors. [PDF]
, 2015 Transforming growth factor beta-1, encoded by the TGFB1 gene, is a cytokine that plays a central role in many physiological and pathogenic processes.
Apperley, JF +13 more
core +2 more sources