Results 61 to 70 of about 9,299,804 (276)

ANALYSIS OF THE LEVEL OF TRANSFORMING GROWTH FACTOR β1 IN CHILDREN WITH BRONCHIAL ASTHMA

open access: yesМать и дитя в Кузбассе, 2019
Achieving control over the symptoms of the disease is the most important and serious task in the treatment of bronchial asthma. The cause of uncontrolled flow may be the activation of tissue growth factors that trigger the process of remodeling the ...
Наталья Леонидовна Потапова   +1 more
doaj  

Vascular reactivity modulation by exposure to serum from patients with Marfan syndrome in healthy rat aortic rings

open access: yesHeliyon
Introduction: Marfan syndrome is a rare disease in which different metabolic pathways and immune mediators such as transforming growth factor β1, interleukins and metalloproteinases participate.
María Elena Soto   +8 more
doaj   +1 more source

Transforming growth factor beta-1 (TGF-β1) expression in patients with adenomyosis [PDF]

open access: yesRevista Brasileira de Ginecologia e Obstetrícia
Objective: To compare Transforming growth factor beta-1 (TGF-β1) expression in patients with and without adenomyosis. Methods: A prospective design was performed including 49 patients submitted to hysterectomy.
Andreia Jacobo   +4 more
doaj   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

open access: yesFEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt   +2 more
wiley   +1 more source

The transforming growth factor β1–inducible transcription factor, TIEG1, mediates apoptosis through oxidative stress

open access: yes, 1999
Transforming growth factor β1(TGF‐β1)–inducible transcription factors have recently elicited interest because of their critical role in the regulation of cell proliferation, differentiation, and apoptosis.
Bronk, Steven F   +4 more
core   +1 more source

TGF-β1 Negatively Regulates the Number and Function of Hematopoietic Stem Cells

open access: yesStem Cell Reports, 2018
Summary: Transforming growth factor β1 (TGF-β1) plays a role in the maintenance of quiescent hematopoietic stem cells (HSCs) in vivo. We asked whether TGF-β1 controls the cell cycle status of HSCs in vitro to enhance the reconstitution activity.
Xiaofang Wang   +14 more
doaj   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Transforming growth factor–β1 mediated CHST11 and CHSY1 mRNA expression is ROS dependent in vascular smooth muscle cells

open access: yes, 2018
Transforming growth factor (TGF)-β1 mediates glycosaminoglycan (GAG) chain hyperelongation on secreted proteoglycans and these modifications are associated with increased lipid binding in the vessel wall and the development of atherosclerosis.
Kamato, Danielle   +7 more
core   +1 more source

Platelet-Derived Growth Factor and Transforming Growth Factor β1 Regulate ARDS-Associated Lung Fibrosis Through Distinct Signaling Pathways

open access: yesCellular Physiology and Biochemistry, 2015
Background/Aims: Severe acute lung injury (ALI) often develops into acute respiratory distress syndrome (ARDS). Previous studies have shown that platelet-derived growth factor (PDGF) and transforming growth factor β1 (TGFβ1) participate in the ...
Xingqi Deng   +5 more
doaj   +1 more source

MicroRNA-34a Promotes EMT and Liver Fibrosis in Primary Biliary Cholangitis by Regulating TGF-β1/smad Pathway

open access: yesJournal of Immunology Research, 2021
Background and Aims. Primary biliary cholangitis (PBC) is an autoimmune cholestatic liver disease. We found microRNA-34a (miR-34a), as the downstream gene of p53, was overexpressed in some of fibrogenic diseases.
Ying Pan   +3 more
doaj   +1 more source

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