Results 211 to 220 of about 202,654 (267)

Artemisinin exerts anti-inflammatory effects in osteoarthritis through the inhibition of TGF-β1 signaling. [PDF]

Front Immunol
Zheng X, Yu B, Song Y, Chen Y, Li Z, Yao J.   +5 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Experimental Study of YaJieShaBa Antialcoholic Hepatic Fibrosis Through TGF-β1/Smad Signaling Pathway. [PDF]

Mediators Inflamm
Zhang L, Bai Y, Luo S, Liu F, Zheng L, Wan Y, Wu X, Chen Q, Xie Y, Guo P.   +9 more
europepmc   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Deletion of Tgf-β1 From CD206⁺ M2 Macrophages Ameliorates Obesity-Induced Suppression of Myogenesis and AMPK Phosphorylation in Skeletal Muscle. [PDF]

J Cachexia Sarcopenia Muscle
Bilal M, Anh LD, Phuong NQ, Khalid S, Nawaz A, Memoona, Aslam MR, Kado T, Watanabe Y, Nishimura A, Igarashi Y, Sharif A, Onogi Y, Wada T, Hayashi R, Hirabayashi K, Yamamoto S, Nakagawa T, Mori H, Usui I, Kato M, Fujisaka S, Tobe K.   +22 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

IL-6 and TGF-β1 as biomarkers of schistosomiasis-associated pulmonary hypertension in a murine model. [PDF]

Braz J Med Biol Res
Roque AC, Stockmann IS, Acencio MMP, Silva CSR, Espírito-Santo MCD, Pinto PLS, Mauad T, Irigoyen MC, Crajoinas RO, Souza R, Salibe-Filho W.   +10 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

CCN1 drives asthmatic airway remodeling through amplification of TGF-β1/Smad3 signaling. [PDF]

Respir Res
Wang Y, Xu C, Zeng R, Liu X, Zhang J, Pan Y, Qi Q, Qiao C, Shi S, Wang P, Liu X, Gao M, Gao T, Dong L.   +13 more
europepmc   +1 more source