Results 211 to 220 of about 166,365 (294)

Huanggan decoction ameliorates cholestatic hepatic fibrosis in rats via TGF-β1/Smad3 signaling pathway. [PDF]

PLoS One
Lei Y, Ma X, Jin X, He Y, Yang J, Zhao Y, Chen J, Gao T.   +7 more
europepmc   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

BMAL1 attenuates myocardial infarction-induced fibrosis via suppressing p-SMAD3/SMAD3 in TGF-β1 pathway. [PDF]

Biochem Biophys Rep
Zhang D, Wang H, Gu Z, Zhang L, Hu Z, Wang Y.   +5 more
europepmc   +1 more source

Rupestonic Acid of Artemisia Rupestris L. Extract Treats Pulmonary Fibrosis in COPD by Targeting TGF-β1. [PDF]

Adv Sci (Weinh)
Peng L, Zhang L, Fan Y, Huang S, Zhao Q, Han C, Hao Z.   +6 more
europepmc   +1 more source

Mitochondrial mGPDH Modulates Fibroblast Function in Diabetic Wound Healing via the SIRT1-c-Myc-TGF-β1 Axis. [PDF]

Diabetes
Zhou L, Hong Y, Li X, Zhang Y, Zhang L, Peng G, Qu H, Liao X, Liao M, Yang Y, Cheng L, Leng W, Zheng Y, Zhang Y, Zheng H, Long M.   +15 more
europepmc   +1 more source

Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis. [PDF]

Mol Med Rep
Han Y, Yang S, Zhang J, Wang Y, Zhao X, Liu H.   +5 more
europepmc   +1 more source

Cardiomyocyte-derived HSPB1 regulates TGF-β1 maturation and inhibits endothelial-to-mesenchymal transition in myocardial fibrosis. [PDF]

iScience
Wang J, Fu A, Tan G, Yang H, Zhou J, Peng J, Zhang Q, Liu X.   +7 more
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

TGF-β1 modulates PFC glial cell activation to facilitate exercise-induced analgesia in mice with spared nerve injury. [PDF]

IBRO Neurosci Rep
Kong Y, Wu J, Sun X, Wang C, He H.
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source