Results 181 to 190 of about 113,223 (329)

Interleukin-26, preferentially produced by TH17 lymphocytes, regulates CNS barrier function. [PDF]

open access: yesNeurol Neuroimmunol Neuroinflamm, 2020
Broux B   +19 more
europepmc   +1 more source

Activating α7nAChR suppresses systemic inflammation by mitigating neuroinflammation of the medullary visceral zone in sepsis in a rat model

open access: yesTranslational Neuroscience
Our previous studies have shown that activating α7nAChRs suppresses systemic inflammation and immunity through the cholinergic anti-inflammatory pathway (CAP) in early sepsis.
Peng Lin   +3 more
doaj   +1 more source

Selective Impairment of TH17-Differentiation and Protection against Autoimmune Arthritis after Overexpression of BCL2A1 in T Lymphocytes

open access: gold, 2016
Marcos Iglesias   +6 more
openalex   +2 more sources

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

New Technologies Empower Hemophilic Arthropathy Treatment: Focusing on Regenerative Medicine, Molecular Targeting, and Gene Therapy

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Hemophilic arthropathy (HA), a major complication of hemophilia, is a chronic osteoarthropathy driven by repeated joint bleeding. Although traditional therapies such as coagulation factor replacement, physical rehabilitation, and surgery can manage symptoms, they cannot fundamentally repair established joint damage or break the pathological ...
Lin Sun   +8 more
wiley   +1 more source

STUDIES OF NATURAL T LYMPHOCYTES : iNKT17 and Th17.

open access: yes, 2012
The thymus is an organ for the development of T lymphocytes, part of the immune system. These cells are commonly associated with the adaptive immune system, although some populations, including Tγδ and iNKT cells, are associated with the innate immune system.
openaire   +1 more source

Constipation Is Linked to Neuroinflammation in Early Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Constipation is a risk factor for the onset and accelerated progression of Parkinson's disease (PD), but the mechanisms underlying this association are unknown. Neuroinflammation in PD has been demonstrated in postmortem and neuroimaging studies; however, its relationship with constipation has not been investigated.
Marta Camacho   +8 more
wiley   +1 more source

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